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Rapidly progressing facial leishmaniasis: effective treatment with liposomal amphotericin B and a review of the management of Old World cutaneous leishmaniasis.
Paediatr Int Child Health. 2018 05; 38(2):158-161.PI

Abstract

Cutaneous leishmaniasis (CL), a common condition in many parts of the world, is being increasingly encountered in non-endemic countries secondary to immigration. The clinical manifestations and course can vary substantially, with appropriate management ranging from observation for self-healing lesions to urgent treatment to prevent damaging anatomical and cosmetic sequelae. While there are now several effective medications, optimal therapy is not well defined, and decision-making can be challenged by the location of lesions and various drug issues, including availability, mode of delivery and adverse effects. A 7-year-old Afghani boy who presented shortly after arriving in the United States with a rapidly progressing crusting and ulcerative facial rash caused by Leishmania tropica is described. The various drugs currently available for CL and experience of using liposomal amphotericin B specifically are reviewed.

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Publisher Full Text

Authors+Show Affiliations

Islam S
a Division of Pediatric Infectious Diseases , University at Buffalo, State University of New York , Buffalo , NY , USA.

MeSH

Amphotericin BAntiprotozoal AgentsChildFacial DermatosesHumansLeishmania tropicaLeishmaniasis, CutaneousMaleTreatment OutcomeUnited States

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

28281913

Citation

Islam, Shamim. "Rapidly Progressing Facial Leishmaniasis: Effective Treatment With Liposomal Amphotericin B and a Review of the Management of Old World Cutaneous Leishmaniasis." Paediatrics and International Child Health, vol. 38, no. 2, 2018, pp. 158-161.
Islam S. Rapidly progressing facial leishmaniasis: effective treatment with liposomal amphotericin B and a review of the management of Old World cutaneous leishmaniasis. Paediatr Int Child Health. 2018;38(2):158-161.
Islam, S. (2018). Rapidly progressing facial leishmaniasis: effective treatment with liposomal amphotericin B and a review of the management of Old World cutaneous leishmaniasis. Paediatrics and International Child Health, 38(2), 158-161. https://doi.org/10.1080/20469047.2017.1296216
Islam S. Rapidly Progressing Facial Leishmaniasis: Effective Treatment With Liposomal Amphotericin B and a Review of the Management of Old World Cutaneous Leishmaniasis. Paediatr Int Child Health. 2018;38(2):158-161. PubMed PMID: 28281913.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Rapidly progressing facial leishmaniasis: effective treatment with liposomal amphotericin B and a review of the management of Old World cutaneous leishmaniasis. A1 - Islam,Shamim, Y1 - 2017/03/10/ PY - 2017/3/11/pubmed PY - 2018/11/13/medline PY - 2017/3/11/entrez KW - Cutaneous leishmaniasis KW - Leishmania tropica KW - immigrant and refugee health KW - liposomal amphotericin B (L-Amb) SP - 158 EP - 161 JF - Paediatrics and international child health JO - Paediatr Int Child Health VL - 38 IS - 2 N2 - Cutaneous leishmaniasis (CL), a common condition in many parts of the world, is being increasingly encountered in non-endemic countries secondary to immigration. The clinical manifestations and course can vary substantially, with appropriate management ranging from observation for self-healing lesions to urgent treatment to prevent damaging anatomical and cosmetic sequelae. While there are now several effective medications, optimal therapy is not well defined, and decision-making can be challenged by the location of lesions and various drug issues, including availability, mode of delivery and adverse effects. A 7-year-old Afghani boy who presented shortly after arriving in the United States with a rapidly progressing crusting and ulcerative facial rash caused by Leishmania tropica is described. The various drugs currently available for CL and experience of using liposomal amphotericin B specifically are reviewed. SN - 2046-9055 UR - https://www.unboundmedicine.com/medline/citation/28281913/Rapidly_progressing_facial_leishmaniasis:_effective_treatment_with_liposomal_amphotericin_B_and_a_review_of_the_management_of_Old_World_cutaneous_leishmaniasis_ L2 - https://www.tandfonline.com/doi/full/10.1080/20469047.2017.1296216 DB - PRIME DP - Unbound Medicine ER -