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Zika virus: History, epidemiology, transmission, and clinical presentation.
J Neuroimmunol 2017; 308:50-64JN

Abstract

Zika virus (ZIKV), a mosquito-borne positive-stranded RNA virus of the family Flaviviridae (genus Flavivirus), is now causing an unprecedented large-scale outbreak in the Americas. Historically, ZIKV spread eastward from equatorial Africa and Asia to the Pacific Islands during the late 2000s to early 2010s, invaded the Caribbean and Central and South America in 2015, and reached North America in 2016. Although ZIKV infection generally causes no symptoms or only a mild self-limiting illness, it has recently been linked to a rising number of severe neurological diseases, including microcephaly and Guillain-Barré syndrome. Because of the continuous geographic expansion of both the virus and its mosquito vectors, ZIKV poses a serious threat to public health around the globe. However, there are no vaccines or antiviral therapies available against this pathogen. This review summarizes a fast-growing body of literature on the history, epidemiology, transmission, and clinical presentation of ZIKV and highlights the urgent need for the development of efficient control strategies for this emerging pathogen.

Authors+Show Affiliations

Department of Animal, Dairy, and Veterinary Sciences, College of Agriculture and Applied Sciences, Utah State University, Logan, UT 84322, USA.Department of Animal, Dairy, and Veterinary Sciences, College of Agriculture and Applied Sciences, Utah State University, Logan, UT 84322, USA.Department of Animal, Dairy, and Veterinary Sciences, College of Agriculture and Applied Sciences, Utah State University, Logan, UT 84322, USA.Department of Animal, Dairy, and Veterinary Sciences, College of Agriculture and Applied Sciences, Utah State University, Logan, UT 84322, USA. Electronic address: youngmin.lee@usu.edu.

Pub Type(s)

Historical Article
Journal Article
Review
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

28285789

Citation

Song, Byung-Hak, et al. "Zika Virus: History, Epidemiology, Transmission, and Clinical Presentation." Journal of Neuroimmunology, vol. 308, 2017, pp. 50-64.
Song BH, Yun SI, Woolley M, et al. Zika virus: History, epidemiology, transmission, and clinical presentation. J Neuroimmunol. 2017;308:50-64.
Song, B. H., Yun, S. I., Woolley, M., & Lee, Y. M. (2017). Zika virus: History, epidemiology, transmission, and clinical presentation. Journal of Neuroimmunology, 308, pp. 50-64. doi:10.1016/j.jneuroim.2017.03.001.
Song BH, et al. Zika Virus: History, Epidemiology, Transmission, and Clinical Presentation. J Neuroimmunol. 2017 07 15;308:50-64. PubMed PMID: 28285789.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Zika virus: History, epidemiology, transmission, and clinical presentation. AU - Song,Byung-Hak, AU - Yun,Sang-Im, AU - Woolley,Michael, AU - Lee,Young-Min, Y1 - 2017/03/03/ PY - 2016/12/22/received PY - 2017/03/01/revised PY - 2017/03/01/accepted PY - 2017/3/14/pubmed PY - 2017/8/18/medline PY - 2017/3/14/entrez KW - Arbovirus KW - Flavivirus KW - Guillain-Barré syndrome KW - Microcephaly KW - Mosquito-borne pathogen KW - Zika outbreak KW - Zika pandemic KW - Zika virus SP - 50 EP - 64 JF - Journal of neuroimmunology JO - J. Neuroimmunol. VL - 308 N2 - Zika virus (ZIKV), a mosquito-borne positive-stranded RNA virus of the family Flaviviridae (genus Flavivirus), is now causing an unprecedented large-scale outbreak in the Americas. Historically, ZIKV spread eastward from equatorial Africa and Asia to the Pacific Islands during the late 2000s to early 2010s, invaded the Caribbean and Central and South America in 2015, and reached North America in 2016. Although ZIKV infection generally causes no symptoms or only a mild self-limiting illness, it has recently been linked to a rising number of severe neurological diseases, including microcephaly and Guillain-Barré syndrome. Because of the continuous geographic expansion of both the virus and its mosquito vectors, ZIKV poses a serious threat to public health around the globe. However, there are no vaccines or antiviral therapies available against this pathogen. This review summarizes a fast-growing body of literature on the history, epidemiology, transmission, and clinical presentation of ZIKV and highlights the urgent need for the development of efficient control strategies for this emerging pathogen. SN - 1872-8421 UR - https://www.unboundmedicine.com/medline/citation/28285789/Zika_virus:_History_epidemiology_transmission_and_clinical_presentation_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0165-5728(16)30483-0 DB - PRIME DP - Unbound Medicine ER -