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Malignant syphilis: ostraceous, ulceronecrotic lesions in a patient with human immunodeficiency virus.
Dermatol Online J. 2017 Jan 15; 23(1)DO

Abstract

We present a 36-year-old HIV-positive man with a sixweek history of spreading, ulcerative, and necroticcutaneous lesions. Laboratory and histopathologicexamination revealed syphilis. This case of malignantsyphilis, also known as lues maligna, is an uncommonvariant of this sexually transmitted infection. This casehighlights the importance of including malignantsyphilis in the differential diagnosis of patientspresenting with a disseminated ulcerative andnecrotic rash, especially in individuals with HIV.

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Authors+Show Affiliations

Mohan GC
Department of Pathology, University of Florida, UF Health Jacksonville.
Ali RA
No affiliation info available
Isache CL
No affiliation info available
Sharma RK
No affiliation info available
Perniciaro C
No affiliation info available

MeSH

AdultHIV InfectionsHumansMaleNecrosisSkinSkin UlcerSyphilis, Cutaneous

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

28329469

Citation

Mohan, Girish C., et al. "Malignant Syphilis: Ostraceous, Ulceronecrotic Lesions in a Patient With Human Immunodeficiency Virus." Dermatology Online Journal, vol. 23, no. 1, 2017.
Mohan GC, Ali RA, Isache CL, et al. Malignant syphilis: ostraceous, ulceronecrotic lesions in a patient with human immunodeficiency virus. Dermatol Online J. 2017;23(1).
Mohan, G. C., Ali, R. A., Isache, C. L., Sharma, R. K., & Perniciaro, C. (2017). Malignant syphilis: ostraceous, ulceronecrotic lesions in a patient with human immunodeficiency virus. Dermatology Online Journal, 23(1).
Mohan GC, et al. Malignant Syphilis: Ostraceous, Ulceronecrotic Lesions in a Patient With Human Immunodeficiency Virus. Dermatol Online J. 2017 Jan 15;23(1) PubMed PMID: 28329469.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Malignant syphilis: ostraceous, ulceronecrotic lesions in a patient with human immunodeficiency virus. AU - Mohan,Girish C, AU - Ali,Robert A, AU - Isache,Carmen L, AU - Sharma,Rohit K, AU - Perniciaro,Charles, Y1 - 2017/01/15/ PY - 2017/01/20/received PY - 2017/01/20/accepted PY - 2017/3/23/entrez PY - 2017/3/23/pubmed PY - 2017/10/12/medline JF - Dermatology online journal JO - Dermatol. Online J. VL - 23 IS - 1 N2 - We present a 36-year-old HIV-positive man with a sixweek history of spreading, ulcerative, and necroticcutaneous lesions. Laboratory and histopathologicexamination revealed syphilis. This case of malignantsyphilis, also known as lues maligna, is an uncommonvariant of this sexually transmitted infection. This casehighlights the importance of including malignantsyphilis in the differential diagnosis of patientspresenting with a disseminated ulcerative andnecrotic rash, especially in individuals with HIV. SN - 1087-2108 UR - https://www.unboundmedicine.com/medline/citation/28329469/Malignant_syphilis:_ostraceous_ulceronecrotic_lesions_in_a_patient_with_human_immunodeficiency_virus_ L2 - http://escholarship.org/uc/item/3ps899bh DB - PRIME DP - Unbound Medicine ER -