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Cutaneous manifestations of disseminated gonococcemia.
Dermatol Online J. 2017 Jan 15; 23(1)DO

Abstract

BACKGROUND

Sexually transmitted infections, includingurogenital gonorrheal infection, are a growing healthconcern in the United States. Nearly 50% of cervicalinfections are asymptomatic. If left undiagnosedand untreated, there is a risk of disseminatedinfection.

PURPOSE

To describe an 18-year-old womanpresenting with disseminated gonococcal infectionconfirmed by blood cultures, skin biopsy, and urinegonococcal probe. We also describe the presentation,diagnosis, and treatment of disseminated gonococcalinfection, including discussion of the variousmorphologies of cutaneous lesions that have beenreported in the literature.

MATERIALS AND METHODS

Thefeatures of a woman with disseminated gonococcalinfection are presented. Using PubMed, the termscutaneous, disseminated, gonococcal, gonorrhea,infection, lesions, manifestations, pustules, skin, andsystemic were searched. Relevant citations wereutilized and discussed.

RESULTS

Hemorrhagic pustules,petechiae, and purpuric lesions developed in a youngwoman with fever and joint pain. Blood cultures grewbeta lactamase negative Neisseria gonorrhoeae andthe Neisseria gonorrhoeae/Chlamydia trachomatisprobe was positive for both N. gonorrhoeae and C.trachomatis. Biopsy revealed bulla with neutrophils,extravasated erythrocytes, fibrin deposits in the vesselwalls, and leukocytoclasia.

CONCLUSION

Cutaneouslesions of disseminated gonococcal infection caninclude abscesses, cellulitis, petechiae, purpuricmacules, necrotizing fasciitis, and vasculitis. It isimportant for the clinician to recognize the clinicalsigns and symptoms of disseminated gonococcalinfection, particularly the various cutaneousmanifestations.

Authors+Show Affiliations

Medical School, Louisiana State University Health Sciences Center, New Orleans. Sbeat2@lsuhsc.edu.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

28329470

Citation

Beatrous, Surget V., et al. "Cutaneous Manifestations of Disseminated Gonococcemia." Dermatology Online Journal, vol. 23, no. 1, 2017.
Beatrous SV, Grisoli SB, Riahi RR, et al. Cutaneous manifestations of disseminated gonococcemia. Dermatol Online J. 2017;23(1).
Beatrous, S. V., Grisoli, S. B., Riahi, R. R., Matherne, R. J., & Matherne, R. J. (2017). Cutaneous manifestations of disseminated gonococcemia. Dermatology Online Journal, 23(1).
Beatrous SV, et al. Cutaneous Manifestations of Disseminated Gonococcemia. Dermatol Online J. 2017 Jan 15;23(1) PubMed PMID: 28329470.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cutaneous manifestations of disseminated gonococcemia. AU - Beatrous,Surget V, AU - Grisoli,Stratton B, AU - Riahi,Ryan R, AU - Matherne,Ryan J, AU - Matherne,Ryan J, Y1 - 2017/01/15/ PY - 2017/01/20/received PY - 2017/01/20/accepted PY - 2017/3/23/entrez PY - 2017/3/23/pubmed PY - 2017/10/12/medline JF - Dermatology online journal JO - Dermatol. Online J. VL - 23 IS - 1 N2 - BACKGROUND: Sexually transmitted infections, includingurogenital gonorrheal infection, are a growing healthconcern in the United States. Nearly 50% of cervicalinfections are asymptomatic. If left undiagnosedand untreated, there is a risk of disseminatedinfection. PURPOSE: To describe an 18-year-old womanpresenting with disseminated gonococcal infectionconfirmed by blood cultures, skin biopsy, and urinegonococcal probe. We also describe the presentation,diagnosis, and treatment of disseminated gonococcalinfection, including discussion of the variousmorphologies of cutaneous lesions that have beenreported in the literature. MATERIALS AND METHODS: Thefeatures of a woman with disseminated gonococcalinfection are presented. Using PubMed, the termscutaneous, disseminated, gonococcal, gonorrhea,infection, lesions, manifestations, pustules, skin, andsystemic were searched. Relevant citations wereutilized and discussed. RESULTS: Hemorrhagic pustules,petechiae, and purpuric lesions developed in a youngwoman with fever and joint pain. Blood cultures grewbeta lactamase negative Neisseria gonorrhoeae andthe Neisseria gonorrhoeae/Chlamydia trachomatisprobe was positive for both N. gonorrhoeae and C.trachomatis. Biopsy revealed bulla with neutrophils,extravasated erythrocytes, fibrin deposits in the vesselwalls, and leukocytoclasia. CONCLUSION: Cutaneouslesions of disseminated gonococcal infection caninclude abscesses, cellulitis, petechiae, purpuricmacules, necrotizing fasciitis, and vasculitis. It isimportant for the clinician to recognize the clinicalsigns and symptoms of disseminated gonococcalinfection, particularly the various cutaneousmanifestations. SN - 1087-2108 UR - https://www.unboundmedicine.com/medline/citation/28329470/Cutaneous_manifestations_of_disseminated_gonococcemia L2 - http://escholarship.org/uc/item/33b24006 DB - PRIME DP - Unbound Medicine ER -