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Genetic polymorphisms for 19 autosomal STR loci of Chongqing Han ethnicity and phylogenetic structure exploration among 28 Chinese populations.
Int J Legal Med. 2017 Nov; 131(6):1539-1542.IJ

Abstract

The allele frequencies and forensic statistical parameters of 19 autosomal short tandem repeat (STR) loci (D8S1179, D21S11, D7S820, CSF1P0, D3S1358, THOl, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818, FGA, D6S1043, Penta D, Penta E, and D12S391) included in the Goldeneye™ DNA ID system 20A kit were obtained in 671 Chinese Han individuals residing in Chongqing, Southwest China. All 19 STR loci were identified in agreement with the Hardy-Weinberg equilibrium. A total of 238 alleles were observed with corresponding allele frequencies that varied from 0.0007 to 0.5119. The combined power of discrimination and the combined probability of exclusion for 19 STR loci in the Chongqing Han population were 0.99999999999999999999998954 and 0.99999998387, respectively. The findings indicated that the 19 autosomal STR loci were highly polymorphic in the Chongqing Han population and can be used as a powerful tool in personal identification and parentage testing. Our genetic study enriched the Chinese local forensic reference database. Population comparisons and phylogenetic analyses revealed that genetic heterogeneity widely existed among the Chongqing Han, Xinjiang Uyghur, and Kazakh populations as well as demonstrated that genetic similarity was tightly associated with those of close geographic origin or of the same ethnic origin.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Department of Forensic Medicine, College of Basic Medicine, Chongqing Medical University, Chongqing, 400016, China.

Department of Forensic Medicine, College of Basic Medicine, Chongqing Medical University, Chongqing, 400016, China.

Department of Forensic Genetics, Institute of Forensic Science, Guangzhou Public Security Bureau, Guangzhou, Guangdong, 510000, China.

Department of Forensic Medicine, College of Basic Medicine, Chongqing Medical University, Chongqing, 400016, China.

Department of Forensic Medicine, College of Basic Medicine, Chongqing Medical University, Chongqing, 400016, China.

Department of Forensic Medicine, College of Basic Medicine, Chongqing Medical University, Chongqing, 400016, China.

Department of Forensic Medicine, College of Basic Medicine, Chongqing Medical University, Chongqing, 400016, China.

Department of Forensic Medicine, College of Basic Medicine, Chongqing Medical University, Chongqing, 400016, China.

Department of Forensic Medicine, College of Basic Medicine, Chongqing Medical University, Chongqing, 400016, China. renktang2012@163.com.

MeSH

ChinaDNA FingerprintingEthnic GroupsGene FrequencyGenetics, PopulationHumansMicrosatellite RepeatsPhylogenyPolymorphism, Genetic

Pub Type(s)

Journal Article

Language

eng

PubMed ID

28342005

Citation

Zou, Xing, et al. "Genetic Polymorphisms for 19 Autosomal STR Loci of Chongqing Han Ethnicity and Phylogenetic Structure Exploration Among 28 Chinese Populations." International Journal of Legal Medicine, vol. 131, no. 6, 2017, pp. 1539-1542.

Zou X, Li Y, Li P, et al. Genetic polymorphisms for 19 autosomal STR loci of Chongqing Han ethnicity and phylogenetic structure exploration among 28 Chinese populations. Int J Legal Med. 2017;131(6):1539-1542.

Zou, X., Li, Y., Li, P., Nie, Q., Wang, T., Hu, Y., Zhu, Y., Li, J., & Tang, R. (2017). Genetic polymorphisms for 19 autosomal STR loci of Chongqing Han ethnicity and phylogenetic structure exploration among 28 Chinese populations. International Journal of Legal Medicine, 131(6), 1539-1542. https://doi.org/10.1007/s00414-017-1577-7

Zou X, et al. Genetic Polymorphisms for 19 Autosomal STR Loci of Chongqing Han Ethnicity and Phylogenetic Structure Exploration Among 28 Chinese Populations. Int J Legal Med. 2017;131(6):1539-1542. PubMed PMID: 28342005.

* Article titles in AMA citation format should be in sentence-case

TY - JOUR T1 - Genetic polymorphisms for 19 autosomal STR loci of Chongqing Han ethnicity and phylogenetic structure exploration among 28 Chinese populations. AU - Zou,Xing, AU - Li,YongGuo, AU - Li,Ping, AU - Nie,QianYun, AU - Wang,Ting, AU - Hu,Yue, AU - Zhu,Ying, AU - Li,JianBo, AU - Tang,RenKuan, Y1 - 2017/03/24/ PY - 2017/01/22/received PY - 2017/03/16/accepted PY - 2017/3/28/pubmed PY - 2018/8/10/medline PY - 2017/3/26/entrez KW - Chongqing Han KW - Forensic genetics KW - Genetic polymorphism KW - Short tandem repeat SP - 1539 EP - 1542 JF - International journal of legal medicine JO - Int J Legal Med VL - 131 IS - 6 N2 - The allele frequencies and forensic statistical parameters of 19 autosomal short tandem repeat (STR) loci (D8S1179, D21S11, D7S820, CSF1P0, D3S1358, THOl, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818, FGA, D6S1043, Penta D, Penta E, and D12S391) included in the Goldeneye™ DNA ID system 20A kit were obtained in 671 Chinese Han individuals residing in Chongqing, Southwest China. All 19 STR loci were identified in agreement with the Hardy-Weinberg equilibrium. A total of 238 alleles were observed with corresponding allele frequencies that varied from 0.0007 to 0.5119. The combined power of discrimination and the combined probability of exclusion for 19 STR loci in the Chongqing Han population were 0.99999999999999999999998954 and 0.99999998387, respectively. The findings indicated that the 19 autosomal STR loci were highly polymorphic in the Chongqing Han population and can be used as a powerful tool in personal identification and parentage testing. Our genetic study enriched the Chinese local forensic reference database. Population comparisons and phylogenetic analyses revealed that genetic heterogeneity widely existed among the Chongqing Han, Xinjiang Uyghur, and Kazakh populations as well as demonstrated that genetic similarity was tightly associated with those of close geographic origin or of the same ethnic origin. SN - 1437-1596 UR - https://www.unboundmedicine.com/medline/citation/28342005/Genetic_polymorphisms_for_19_autosomal_STR_loci_of_Chongqing_Han_ethnicity_and_phylogenetic_structure_exploration_among_28_Chinese_populations_ L2 - https://dx.doi.org/10.1007/s00414-017-1577-7 DB - PRIME DP - Unbound Medicine ER -