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High prevalence of alcohol use disorders in patients with inflammatory skin diseases.
Br J Dermatol 2017; 177(3):837-844BJ

Abstract

BACKGROUND

There is a known association between psoriasis and heavy alcohol consumption. The association between heavy alcohol consumption and other inflammatory skin diseases remains to be defined.

OBJECTIVES

To examine the prevalence of heavy drinking using the Alcohol Use Disorders Identification Test (AUDIT) in patients with inflammatory skin disease.

METHODS

We conducted an observational cross-sectional study in a single hospital outpatient department. We recruited 609 patients with either psoriasis, eczema, cutaneous lupus or other inflammatory disorders, and a reference population with skin lesions. Primary outcome was the proportion of patients in each group with an alcohol use disorder (AUD).

RESULTS

The observed prevalence of AUD was 30·6% in patients with psoriasis, 33·3% in those with eczema, 12·3% in those with cutaneous lupus, 21·8% in those with other inflammatory disease and 14·3% in those with non-inflammatory disease. Odds ratios (OR) for AUD in patients in the inflammatory groups compared with those in the noninflammatory groups, adjusted for age and sex, were as follows: psoriasis 1·65 [95% confidence interval (CI) 0·86-3·17], eczema 2·00 (95% CI 1·03-3·85), lupus 1·03 (95% CI 0·39-2·71), other inflammatory disease 1·32 (95% CI 0·68-2·56). ORs were reduced if also adjusted for Dermatology Life Quality Index (DLQI). The prevalence of DLQI ≥ 11 was 31·1% for psoriasis, 43·7% for eczema, 17·5% for cutaneous lupus, 17·2% for other inflammatory disease and 2·8% for noninflammatory disease.

CONCLUSIONS

Patients with eczema attending a hospital clinic have been shown to have high levels of AUD of a similar level to patients with psoriasis and higher than patients with noninflammatory skin diseases.

Authors+Show Affiliations

Newcastle Dermatology, Newcastle University and Newcastle Dermatology, Newcastle Hospitals NHS Trust, Newcastle upon Tyne, U.K.Health and Social Care Institute, Teesside University, Middlesbrough, U.K.Institute of Health and Society, Newcastle University, Newcastle upon Tyne, U.K.Institute of Health and Society, Newcastle University, Newcastle upon Tyne, U.K.Institute of Health and Society, Newcastle University, Newcastle upon Tyne, U.K.Institute of Cellular Medicine, Newcastle University and Newcastle Dermatology, Newcastle Hospitals NHS Trust, Newcastle upon Tyne, U.K.Institute of Health and Society, Newcastle University, Newcastle upon Tyne, U.K.Newcastle Dermatology, Newcastle University and Newcastle Dermatology, Newcastle Hospitals NHS Trust, Newcastle upon Tyne, U.K.

Pub Type(s)

Journal Article
Observational Study

Language

eng

PubMed ID

28346655

Citation

Al-Jefri, K, et al. "High Prevalence of Alcohol Use Disorders in Patients With Inflammatory Skin Diseases." The British Journal of Dermatology, vol. 177, no. 3, 2017, pp. 837-844.
Al-Jefri K, Newbury-Birch D, Muirhead CR, et al. High prevalence of alcohol use disorders in patients with inflammatory skin diseases. Br J Dermatol. 2017;177(3):837-844.
Al-Jefri, K., Newbury-Birch, D., Muirhead, C. R., Gilvarry, E., Araújo-Soares, V., Reynolds, N. J., ... Hampton, P. J. (2017). High prevalence of alcohol use disorders in patients with inflammatory skin diseases. The British Journal of Dermatology, 177(3), pp. 837-844. doi:10.1111/bjd.15497.
Al-Jefri K, et al. High Prevalence of Alcohol Use Disorders in Patients With Inflammatory Skin Diseases. Br J Dermatol. 2017;177(3):837-844. PubMed PMID: 28346655.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - High prevalence of alcohol use disorders in patients with inflammatory skin diseases. AU - Al-Jefri,K, AU - Newbury-Birch,D, AU - Muirhead,C R, AU - Gilvarry,E, AU - Araújo-Soares,V, AU - Reynolds,N J, AU - Kaner,E, AU - Hampton,P J, Y1 - 2017/07/07/ PY - 2017/03/20/accepted PY - 2017/3/28/pubmed PY - 2018/7/24/medline PY - 2017/3/28/entrez SP - 837 EP - 844 JF - The British journal of dermatology JO - Br. J. Dermatol. VL - 177 IS - 3 N2 - BACKGROUND: There is a known association between psoriasis and heavy alcohol consumption. The association between heavy alcohol consumption and other inflammatory skin diseases remains to be defined. OBJECTIVES: To examine the prevalence of heavy drinking using the Alcohol Use Disorders Identification Test (AUDIT) in patients with inflammatory skin disease. METHODS: We conducted an observational cross-sectional study in a single hospital outpatient department. We recruited 609 patients with either psoriasis, eczema, cutaneous lupus or other inflammatory disorders, and a reference population with skin lesions. Primary outcome was the proportion of patients in each group with an alcohol use disorder (AUD). RESULTS: The observed prevalence of AUD was 30·6% in patients with psoriasis, 33·3% in those with eczema, 12·3% in those with cutaneous lupus, 21·8% in those with other inflammatory disease and 14·3% in those with non-inflammatory disease. Odds ratios (OR) for AUD in patients in the inflammatory groups compared with those in the noninflammatory groups, adjusted for age and sex, were as follows: psoriasis 1·65 [95% confidence interval (CI) 0·86-3·17], eczema 2·00 (95% CI 1·03-3·85), lupus 1·03 (95% CI 0·39-2·71), other inflammatory disease 1·32 (95% CI 0·68-2·56). ORs were reduced if also adjusted for Dermatology Life Quality Index (DLQI). The prevalence of DLQI ≥ 11 was 31·1% for psoriasis, 43·7% for eczema, 17·5% for cutaneous lupus, 17·2% for other inflammatory disease and 2·8% for noninflammatory disease. CONCLUSIONS: Patients with eczema attending a hospital clinic have been shown to have high levels of AUD of a similar level to patients with psoriasis and higher than patients with noninflammatory skin diseases. SN - 1365-2133 UR - https://www.unboundmedicine.com/medline/citation/28346655/High_prevalence_of_alcohol_use_disorders_in_patients_with_inflammatory_skin_diseases_ L2 - https://doi.org/10.1111/bjd.15497 DB - PRIME DP - Unbound Medicine ER -