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Fruit and vegetable intake and breast cancer prognosis: a meta-analysis of prospective cohort studies.
Br J Nutr 2017; 117(5):737-749BJ

Abstract

The effect of fruit and vegetable intake on breast cancer prognosis is controversial. Thus, a meta-analysis was carried out to explore their associations. A comprehensive search was conducted in PubMed, Web of Science, OVID, ProQuest and Chinese databases from inception to April 2016. The summary hazard ratios (HR) and 95 % CI were estimated using a random effects model if substantial heterogeneity existed and using a fixed effects model if not. Subgroup analyses and sensitivity analyses were also performed. In total, twelve studies comprising 41 185 participants were included in the meta-analysis. Comparing the highest with the lowest, the summary HR for all-cause mortality were 1·01 (95 % CI 0·72, 1·42) for fruits and vegetables combined, 0·96 (95 % CI 0·83, 1·12) for total vegetable intake, 0·99 (95 % CI 0·89, 1·11) for cruciferous vegetable intake and 0·88 (95 % CI 0·74, 1·05) for fruit intake; those for breast cancer-specific mortality were 1·05 (95 % CI 0·77, 1·43) for total vegetable intake and 0·94 (95 % CI 0·69, 1·26) for fruit intake; and those for breast cancer recurrence were 0·89 (95 % CI 0·53, 1·50) for total vegetable intake and 0·98 (95 % CI 0·76, 1·26) for cruciferous vegetable intake. This meta-analysis found no significant associations between fruit and vegetable intake and breast cancer prognosis.

Authors+Show Affiliations

1Department of Medical Statistics and Epidemiology,School of Public Health,Sun Yat-Sen University,Guangzhou 510080,People's Republic of China.1Department of Medical Statistics and Epidemiology,School of Public Health,Sun Yat-Sen University,Guangzhou 510080,People's Republic of China.1Department of Medical Statistics and Epidemiology,School of Public Health,Sun Yat-Sen University,Guangzhou 510080,People's Republic of China.

Pub Type(s)

Journal Article
Meta-Analysis

Language

eng

PubMed ID

28366183

Citation

Peng, Chen, et al. "Fruit and Vegetable Intake and Breast Cancer Prognosis: a Meta-analysis of Prospective Cohort Studies." The British Journal of Nutrition, vol. 117, no. 5, 2017, pp. 737-749.
Peng C, Luo WP, Zhang CX. Fruit and vegetable intake and breast cancer prognosis: a meta-analysis of prospective cohort studies. Br J Nutr. 2017;117(5):737-749.
Peng, C., Luo, W. P., & Zhang, C. X. (2017). Fruit and vegetable intake and breast cancer prognosis: a meta-analysis of prospective cohort studies. The British Journal of Nutrition, 117(5), pp. 737-749. doi:10.1017/S0007114517000423.
Peng C, Luo WP, Zhang CX. Fruit and Vegetable Intake and Breast Cancer Prognosis: a Meta-analysis of Prospective Cohort Studies. Br J Nutr. 2017;117(5):737-749. PubMed PMID: 28366183.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Fruit and vegetable intake and breast cancer prognosis: a meta-analysis of prospective cohort studies. AU - Peng,Chen, AU - Luo,Wei-Ping, AU - Zhang,Cai-Xia, Y1 - 2017/04/03/ PY - 2017/4/4/pubmed PY - 2017/4/21/medline PY - 2017/4/4/entrez KW - HR hazard ratio KW - Breast cancer KW - Fruits and vegetables KW - Meta-analyses KW - Mortality KW - Recurrence SP - 737 EP - 749 JF - The British journal of nutrition JO - Br. J. Nutr. VL - 117 IS - 5 N2 - The effect of fruit and vegetable intake on breast cancer prognosis is controversial. Thus, a meta-analysis was carried out to explore their associations. A comprehensive search was conducted in PubMed, Web of Science, OVID, ProQuest and Chinese databases from inception to April 2016. The summary hazard ratios (HR) and 95 % CI were estimated using a random effects model if substantial heterogeneity existed and using a fixed effects model if not. Subgroup analyses and sensitivity analyses were also performed. In total, twelve studies comprising 41 185 participants were included in the meta-analysis. Comparing the highest with the lowest, the summary HR for all-cause mortality were 1·01 (95 % CI 0·72, 1·42) for fruits and vegetables combined, 0·96 (95 % CI 0·83, 1·12) for total vegetable intake, 0·99 (95 % CI 0·89, 1·11) for cruciferous vegetable intake and 0·88 (95 % CI 0·74, 1·05) for fruit intake; those for breast cancer-specific mortality were 1·05 (95 % CI 0·77, 1·43) for total vegetable intake and 0·94 (95 % CI 0·69, 1·26) for fruit intake; and those for breast cancer recurrence were 0·89 (95 % CI 0·53, 1·50) for total vegetable intake and 0·98 (95 % CI 0·76, 1·26) for cruciferous vegetable intake. This meta-analysis found no significant associations between fruit and vegetable intake and breast cancer prognosis. SN - 1475-2662 UR - https://www.unboundmedicine.com/medline/citation/28366183/Fruit_and_vegetable_intake_and_breast_cancer_prognosis:_a_meta_analysis_of_prospective_cohort_studies_ L2 - https://www.cambridge.org/core/product/identifier/S0007114517000423/type/journal_article DB - PRIME DP - Unbound Medicine ER -