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Successful Management of Zoon's Balanitis with Topical Mupirocin Ointment: A Case Report and Literature Review of Mupirocin-Responsive Balanitis Circumscripta Plasmacelluaris.
Dermatol Ther (Heidelb). 2017 Jun; 7(2):203-210.DT

Abstract

INTRODUCTION

Zoon's balanitis, also referred to as balanitis circumscripta plasmacellularis (BCP), is an idiopathic, benign inflammatory condition of the glans penis and foreskin most often seen in elderly uncircumcised men. A patient with a biopsy-confirmed diagnosis of BCP who was successfully treated with topical mupirocin ointment is described.

METHODS

The PubMed database was searched with the key words: bactroban, balanitis, cell, circumscripta, mupirocin, plasma, plasmacellularis, tacrolimus, Zoon. The papers generated by the search and their references were reviewed.

RESULTS

Treatments for BCP have previously included circumcision and topical calcineurin inhibitors. Our patient with BCP rapidly resolved after initiating treatment with mupirocin 2% ointment.

CONCLUSION

BCP is a benign dermatosis affecting the glans penis and foreskin. We confirm an earlier observation demonstrating successful management of this condition with topical mupirocin 2% ointment. Previously reported therapies include circumcision, topical calcineurin inhibitors, phototherapy, and laser therapy. However, based on our observations, topical mupirocin 2% ointment therapy may be considered for the initial management of patients with suspected BCP. Prompt response to mupirocin 2% ointment is highly suggestive of the diagnosis of BCP since morphologically similar skin conditions do not respond to this treatment.

Authors+Show Affiliations

School of Medicine, University of California San Diego, La Jolla, CA, USA. obari@ucsd.edu.Department of Dermatology, University of California San Diego, La Jolla, CA, USA. mitehead@gmail.com.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

28382428

Citation

Bari, Omar, and Philip R. Cohen. "Successful Management of Zoon's Balanitis With Topical Mupirocin Ointment: a Case Report and Literature Review of Mupirocin-Responsive Balanitis Circumscripta Plasmacelluaris." Dermatology and Therapy, vol. 7, no. 2, 2017, pp. 203-210.
Bari O, Cohen PR. Successful Management of Zoon's Balanitis with Topical Mupirocin Ointment: A Case Report and Literature Review of Mupirocin-Responsive Balanitis Circumscripta Plasmacelluaris. Dermatol Ther (Heidelb). 2017;7(2):203-210.
Bari, O., & Cohen, P. R. (2017). Successful Management of Zoon's Balanitis with Topical Mupirocin Ointment: A Case Report and Literature Review of Mupirocin-Responsive Balanitis Circumscripta Plasmacelluaris. Dermatology and Therapy, 7(2), 203-210. https://doi.org/10.1007/s13555-017-0178-1
Bari O, Cohen PR. Successful Management of Zoon's Balanitis With Topical Mupirocin Ointment: a Case Report and Literature Review of Mupirocin-Responsive Balanitis Circumscripta Plasmacelluaris. Dermatol Ther (Heidelb). 2017;7(2):203-210. PubMed PMID: 28382428.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Successful Management of Zoon's Balanitis with Topical Mupirocin Ointment: A Case Report and Literature Review of Mupirocin-Responsive Balanitis Circumscripta Plasmacelluaris. AU - Bari,Omar, AU - Cohen,Philip R, Y1 - 2017/04/05/ PY - 2017/03/03/received PY - 2017/4/7/pubmed PY - 2017/4/7/medline PY - 2017/4/7/entrez KW - Bactroban KW - Balanitis KW - Cell KW - Circumscripta KW - Mupirocin KW - Plasma KW - Plasmacellularis KW - Tacrolimus KW - Zoon SP - 203 EP - 210 JF - Dermatology and therapy JO - Dermatol Ther (Heidelb) VL - 7 IS - 2 N2 - INTRODUCTION: Zoon's balanitis, also referred to as balanitis circumscripta plasmacellularis (BCP), is an idiopathic, benign inflammatory condition of the glans penis and foreskin most often seen in elderly uncircumcised men. A patient with a biopsy-confirmed diagnosis of BCP who was successfully treated with topical mupirocin ointment is described. METHODS: The PubMed database was searched with the key words: bactroban, balanitis, cell, circumscripta, mupirocin, plasma, plasmacellularis, tacrolimus, Zoon. The papers generated by the search and their references were reviewed. RESULTS: Treatments for BCP have previously included circumcision and topical calcineurin inhibitors. Our patient with BCP rapidly resolved after initiating treatment with mupirocin 2% ointment. CONCLUSION: BCP is a benign dermatosis affecting the glans penis and foreskin. We confirm an earlier observation demonstrating successful management of this condition with topical mupirocin 2% ointment. Previously reported therapies include circumcision, topical calcineurin inhibitors, phototherapy, and laser therapy. However, based on our observations, topical mupirocin 2% ointment therapy may be considered for the initial management of patients with suspected BCP. Prompt response to mupirocin 2% ointment is highly suggestive of the diagnosis of BCP since morphologically similar skin conditions do not respond to this treatment. SN - 2193-8210 UR - https://www.unboundmedicine.com/medline/citation/28382428/Successful_Management_of_Zoon's_Balanitis_with_Topical_Mupirocin_Ointment:_A_Case_Report_and_Literature_Review_of_Mupirocin_Responsive_Balanitis_Circumscripta_Plasmacelluaris_ L2 - https://dx.doi.org/10.1007/s13555-017-0178-1 DB - PRIME DP - Unbound Medicine ER -
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