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Paraneoplastic palmoplantar keratoderma secondary to metastatic uterine adenocarcinoma.
Cutis. 2017 Mar; 99(3):E32-E35.C

Abstract

Palmoplantar keratoderma (PPK) is a dermatosis that presents as hyperkeratosis of the palms and soles. It may be acquired or heritable. Acquired PPK often occurs as a paraneoplastic response as well as a stigma of other dermatoses. We report a rare case of a 72-year-old woman with acquired PPK secondary to metastatic uterine adenocarcinoma. We also review other rare cases of cutaneous paraneoplasia secondary to uterine cancer and describe the salient features of acquired PPK. Acquired PPK most commonly presents as a paraneoplastic response to visceral malignancies that include localized esophageal, pulmonary, urinary/bladder, and gastric carcinomas, as well as myeloma. Management of acquired PPK includes treatment of the underlying cause. Adjunctive vitamin A analogues have been found to be effective.

Authors+Show Affiliations

Department of Radiology, Wayne State University, Michigan, USA.Division of Dermatology, Department of Medicine, Facey Medical Center, Mission Hills, California, USA.Department of Dermatology, State University of New York Downstate, Brooklyn, USA.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

28398428

Citation

Kallini, Joseph R., et al. "Paraneoplastic Palmoplantar Keratoderma Secondary to Metastatic Uterine Adenocarcinoma." Cutis, vol. 99, no. 3, 2017, pp. E32-E35.
Kallini JR, Sadeghani K, Khachemoune A. Paraneoplastic palmoplantar keratoderma secondary to metastatic uterine adenocarcinoma. Cutis. 2017;99(3):E32-E35.
Kallini, J. R., Sadeghani, K., & Khachemoune, A. (2017). Paraneoplastic palmoplantar keratoderma secondary to metastatic uterine adenocarcinoma. Cutis, 99(3), E32-E35.
Kallini JR, Sadeghani K, Khachemoune A. Paraneoplastic Palmoplantar Keratoderma Secondary to Metastatic Uterine Adenocarcinoma. Cutis. 2017;99(3):E32-E35. PubMed PMID: 28398428.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Paraneoplastic palmoplantar keratoderma secondary to metastatic uterine adenocarcinoma. AU - Kallini,Joseph R, AU - Sadeghani,Khosro, AU - Khachemoune,Amor, PY - 2017/4/12/entrez PY - 2017/4/12/pubmed PY - 2017/7/8/medline SP - E32 EP - E35 JF - Cutis JO - Cutis VL - 99 IS - 3 N2 - Palmoplantar keratoderma (PPK) is a dermatosis that presents as hyperkeratosis of the palms and soles. It may be acquired or heritable. Acquired PPK often occurs as a paraneoplastic response as well as a stigma of other dermatoses. We report a rare case of a 72-year-old woman with acquired PPK secondary to metastatic uterine adenocarcinoma. We also review other rare cases of cutaneous paraneoplasia secondary to uterine cancer and describe the salient features of acquired PPK. Acquired PPK most commonly presents as a paraneoplastic response to visceral malignancies that include localized esophageal, pulmonary, urinary/bladder, and gastric carcinomas, as well as myeloma. Management of acquired PPK includes treatment of the underlying cause. Adjunctive vitamin A analogues have been found to be effective. SN - 2326-6929 UR - https://www.unboundmedicine.com/medline/citation/28398428/Paraneoplastic_palmoplantar_keratoderma_secondary_to_metastatic_uterine_adenocarcinoma_ L2 - http://www.mdedge.com/cutis/article/134742/rare-diseases/paraneoplastic-palmoplantar-keratoderma-secondary-metastatic DB - PRIME DP - Unbound Medicine ER -