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Prehabilitation for the Frail Patient Approaching ESRD.
Semin Nephrol. 2017 03; 37(2):159-172.SN

Abstract

Frailty is a distinct phenotype that is highly prevalent in chronic kidney disease (CKD) and appears to be more prevalent with decreasing glomerular filtration rate. Exercise training or intervention to increase physical activity may ameliorate poor physical functioning and frailty, and even may improve survival in patients with CKD. Although exercise interventions improve outcomes across the spectrum of CKD, including patients treated with dialysis, patients treated with dialysis face barriers to exercise that patients with predialysis CKD do not. Rehabilitation at earlier stages of CKD (or prehabilitation before dialysis) might be more beneficial than not addressing the decreasing physical functioning and low physical activity until patients are receiving dialysis. This review summarizes available literature on frailty in the CKD and end-stage renal disease population, including exercise interventions and the limited evidence for prehabilitation as a strategy.

Authors+Show Affiliations

Nephrology Section, San Francisco VA Medical Center and University of California, San Francisco, CA.Nephrology Section, San Francisco VA Medical Center and University of California, San Francisco, CA. Electronic address: Kirsten.johansen@ucsf.edu.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

28410650

Citation

Sheshadri, Anoop, and Kirsten L. Johansen. "Prehabilitation for the Frail Patient Approaching ESRD." Seminars in Nephrology, vol. 37, no. 2, 2017, pp. 159-172.
Sheshadri A, Johansen KL. Prehabilitation for the Frail Patient Approaching ESRD. Semin Nephrol. 2017;37(2):159-172.
Sheshadri, A., & Johansen, K. L. (2017). Prehabilitation for the Frail Patient Approaching ESRD. Seminars in Nephrology, 37(2), 159-172. https://doi.org/10.1016/j.semnephrol.2016.12.006
Sheshadri A, Johansen KL. Prehabilitation for the Frail Patient Approaching ESRD. Semin Nephrol. 2017;37(2):159-172. PubMed PMID: 28410650.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prehabilitation for the Frail Patient Approaching ESRD. AU - Sheshadri,Anoop, AU - Johansen,Kirsten L, PY - 2017/4/16/entrez PY - 2017/4/16/pubmed PY - 2017/10/25/medline KW - CKD KW - ESRD KW - Frailty KW - exercise KW - physical function KW - prehabilitation SP - 159 EP - 172 JF - Seminars in nephrology JO - Semin Nephrol VL - 37 IS - 2 N2 - Frailty is a distinct phenotype that is highly prevalent in chronic kidney disease (CKD) and appears to be more prevalent with decreasing glomerular filtration rate. Exercise training or intervention to increase physical activity may ameliorate poor physical functioning and frailty, and even may improve survival in patients with CKD. Although exercise interventions improve outcomes across the spectrum of CKD, including patients treated with dialysis, patients treated with dialysis face barriers to exercise that patients with predialysis CKD do not. Rehabilitation at earlier stages of CKD (or prehabilitation before dialysis) might be more beneficial than not addressing the decreasing physical functioning and low physical activity until patients are receiving dialysis. This review summarizes available literature on frailty in the CKD and end-stage renal disease population, including exercise interventions and the limited evidence for prehabilitation as a strategy. SN - 1558-4488 UR - https://www.unboundmedicine.com/medline/citation/28410650/Prehabilitation_for_the_Frail_Patient_Approaching_ESRD_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0270-9295(16)30136-X DB - PRIME DP - Unbound Medicine ER -