Tags

Type your tag names separated by a space and hit enter

Antibacterial efficacy of silver nanoparticles against multi-drug resistant clinical isolates from post-surgical wound infections.
Microb Pathog. 2017 Jun; 107:327-334.MP

Abstract

In order to investigate new effective and inexpensive nano-therapeutic approach for P. aeruginosa, staphylococcus aureus and coagulase negative staphylococci (CoNS), the present study reports an eco-friendly process for rapid synthesis of silver nanoparticles (Ag-NPs) using aqueous leaf extract of Corchorus Capsularis (CRCP). Formation of stable Ag-NPs at different time intervals gives mostly spherical particles with diameters ranging from 5 to 45 nm. The resulting Ag-NPs were characterized using Ultraviolet visible (UV-Vis) spectroscopy, Fourier Transform Infrared (FT-IR) spectroscopy, X-Ray Diffraction (XRD) analysis, Transmission Electron Microscopy (TEM) and Energy Dispersive X-ray analysis (EDX). XRD study shows that the particles are crystalline in nature with face centered cubic geometry. TEM studies show the formation of Ag-NPs with average size of 20.52 nm. The antimicrobial activity of the synthesized Ag-NPs was investigated against multi drug resistant (MDR) P. aeruginosa, Staphylococcus aureus and CoNS isolates from post-surgical wound infections. The present study suggests that Ag-NPs synthesized from aqueous leaf extract of CRCP shows significant antibacterial potential against MDR isolates from post-surgical wound infections.

Authors+Show Affiliations

PG & Research Department of Chemistry, Thiagarajar College, Madurai 625009, India.PG & Research Department of Chemistry, Thiagarajar College, Madurai 625009, India. Electronic address: kmpprakash@gmail.com.Department of Microbiology and Immunology, Institute of Biomedical Sciences, Mekelle University, Mekelle 1871, Ethiopia. Electronic address: saravanan.muthupandian@mu.edu.et.PG & Research Department of Chemistry, Thiagarajar College, Madurai 625009, India.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

28411059

Citation

Kasithevar, Muthupandi, et al. "Antibacterial Efficacy of Silver Nanoparticles Against Multi-drug Resistant Clinical Isolates From Post-surgical Wound Infections." Microbial Pathogenesis, vol. 107, 2017, pp. 327-334.
Kasithevar M, Periakaruppan P, Muthupandian S, et al. Antibacterial efficacy of silver nanoparticles against multi-drug resistant clinical isolates from post-surgical wound infections. Microb Pathog. 2017;107:327-334.
Kasithevar, M., Periakaruppan, P., Muthupandian, S., & Mohan, M. (2017). Antibacterial efficacy of silver nanoparticles against multi-drug resistant clinical isolates from post-surgical wound infections. Microbial Pathogenesis, 107, 327-334. https://doi.org/10.1016/j.micpath.2017.04.013
Kasithevar M, et al. Antibacterial Efficacy of Silver Nanoparticles Against Multi-drug Resistant Clinical Isolates From Post-surgical Wound Infections. Microb Pathog. 2017;107:327-334. PubMed PMID: 28411059.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antibacterial efficacy of silver nanoparticles against multi-drug resistant clinical isolates from post-surgical wound infections. AU - Kasithevar,Muthupandi, AU - Periakaruppan,Prakash, AU - Muthupandian,Saravanan, AU - Mohan,Mahalakshmi, Y1 - 2017/04/11/ PY - 2017/02/10/received PY - 2017/04/05/revised PY - 2017/04/10/accepted PY - 2017/4/16/pubmed PY - 2017/11/29/medline PY - 2017/4/16/entrez KW - Antibacterial efficacy KW - Corchorus Capsularis KW - Multi drug resistant KW - Silver nanoparticles KW - Wound infections SP - 327 EP - 334 JF - Microbial pathogenesis JO - Microb Pathog VL - 107 N2 - In order to investigate new effective and inexpensive nano-therapeutic approach for P. aeruginosa, staphylococcus aureus and coagulase negative staphylococci (CoNS), the present study reports an eco-friendly process for rapid synthesis of silver nanoparticles (Ag-NPs) using aqueous leaf extract of Corchorus Capsularis (CRCP). Formation of stable Ag-NPs at different time intervals gives mostly spherical particles with diameters ranging from 5 to 45 nm. The resulting Ag-NPs were characterized using Ultraviolet visible (UV-Vis) spectroscopy, Fourier Transform Infrared (FT-IR) spectroscopy, X-Ray Diffraction (XRD) analysis, Transmission Electron Microscopy (TEM) and Energy Dispersive X-ray analysis (EDX). XRD study shows that the particles are crystalline in nature with face centered cubic geometry. TEM studies show the formation of Ag-NPs with average size of 20.52 nm. The antimicrobial activity of the synthesized Ag-NPs was investigated against multi drug resistant (MDR) P. aeruginosa, Staphylococcus aureus and CoNS isolates from post-surgical wound infections. The present study suggests that Ag-NPs synthesized from aqueous leaf extract of CRCP shows significant antibacterial potential against MDR isolates from post-surgical wound infections. SN - 1096-1208 UR - https://www.unboundmedicine.com/medline/citation/28411059/Antibacterial_efficacy_of_silver_nanoparticles_against_multi_drug_resistant_clinical_isolates_from_post_surgical_wound_infections_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0882-4010(17)30119-5 DB - PRIME DP - Unbound Medicine ER -