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Epidemiology of Argentine hemorrhagic fever.
Eur J Epidemiol. 1988 Jun; 4(2):259-74.EJ

Abstract

Present knowledge points to horizontal transmission as the most significant mechanism for Junín virus maintenance in the main natural reservoirs, namely Calomys musculinus and Calomys laucha. The existence of naturally infected Akodon azarae, both within and outside the endemic area, as well as the finding that other species, ecologically and phylogenetically related to the main reservoirs, such as Akodon molinae and Calomys callidus, can experimentally develop persistent infections with virus shedding through fauces, suggest a potential role for these cricetids as alternative reservoirs. Furthermore, since those rodents inhabit the borders of the area in which Argentine Hemorrhagic fever is endemic, the risk of spread of this area is to be expected. Whether the establishment of Junín virus persistence in Calomys musculinus and other reservoirs depends on viral or host factors, such as a selective defect in L3T4+ lymphocytes as recently shown for mice, remains to be explored.

Authors+Show Affiliations

Departamento de Microbiología, Facultad de Medicina, Universidad de Buenos Aires, Argentina.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

2841151

Citation

Carballal, G, et al. "Epidemiology of Argentine Hemorrhagic Fever." European Journal of Epidemiology, vol. 4, no. 2, 1988, pp. 259-74.
Carballal G, Videla CM, Merani MS. Epidemiology of Argentine hemorrhagic fever. Eur J Epidemiol. 1988;4(2):259-74.
Carballal, G., Videla, C. M., & Merani, M. S. (1988). Epidemiology of Argentine hemorrhagic fever. European Journal of Epidemiology, 4(2), 259-74.
Carballal G, Videla CM, Merani MS. Epidemiology of Argentine Hemorrhagic Fever. Eur J Epidemiol. 1988;4(2):259-74. PubMed PMID: 2841151.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Epidemiology of Argentine hemorrhagic fever. AU - Carballal,G, AU - Videla,C M, AU - Merani,M S, PY - 1988/6/1/pubmed PY - 1988/6/1/medline PY - 1988/6/1/entrez SP - 259 EP - 74 JF - European journal of epidemiology JO - Eur J Epidemiol VL - 4 IS - 2 N2 - Present knowledge points to horizontal transmission as the most significant mechanism for Junín virus maintenance in the main natural reservoirs, namely Calomys musculinus and Calomys laucha. The existence of naturally infected Akodon azarae, both within and outside the endemic area, as well as the finding that other species, ecologically and phylogenetically related to the main reservoirs, such as Akodon molinae and Calomys callidus, can experimentally develop persistent infections with virus shedding through fauces, suggest a potential role for these cricetids as alternative reservoirs. Furthermore, since those rodents inhabit the borders of the area in which Argentine Hemorrhagic fever is endemic, the risk of spread of this area is to be expected. Whether the establishment of Junín virus persistence in Calomys musculinus and other reservoirs depends on viral or host factors, such as a selective defect in L3T4+ lymphocytes as recently shown for mice, remains to be explored. SN - 0393-2990 UR - https://www.unboundmedicine.com/medline/citation/2841151/Epidemiology_of_Argentine_hemorrhagic_fever_ L2 - https://www.diseaseinfosearch.org/result/3317 DB - PRIME DP - Unbound Medicine ER -