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Intralesional therapy of cutaneous leishmaniasis with sodium stibogluconate antimony.
Br J Dermatol. 1988 Jul; 119(1):53-7.BJ

Abstract

One hundred and thirty lesions of cutaneous leishmaniasis in 60 patients were treated with intralesional injections of Pentostam and 30 lesions were left untreated as controls. The injections were given at 8-day intervals and the patients followed-up for 42 days. One hundred and four lesions (80%) needed one injection only, 20 (15.4%) needed two and six (4.6%) needed three injections. One hundred and twenty three of the treated lesions (94.6%) showed a good clinical response with complete healing or marked improvement within the follow-up period. None of the control lesions showed marked improvement or complete healing. Scarring was minimal or absent following healing of treated lesions. The only side-effect was some localized pain following the injection. We recommend intralesional Pentostam as a safe and effective method of treating acute cutaneous leishmaniasis.

Authors+Show Affiliations

Department of Dermatology, College of Medicine, University of Baghdad, Iraq.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

2841964

Citation

Sharquie, K E., et al. "Intralesional Therapy of Cutaneous Leishmaniasis With Sodium Stibogluconate Antimony." The British Journal of Dermatology, vol. 119, no. 1, 1988, pp. 53-7.
Sharquie KE, Al-Talib KK, Chu AC. Intralesional therapy of cutaneous leishmaniasis with sodium stibogluconate antimony. Br J Dermatol. 1988;119(1):53-7.
Sharquie, K. E., Al-Talib, K. K., & Chu, A. C. (1988). Intralesional therapy of cutaneous leishmaniasis with sodium stibogluconate antimony. The British Journal of Dermatology, 119(1), 53-7.
Sharquie KE, Al-Talib KK, Chu AC. Intralesional Therapy of Cutaneous Leishmaniasis With Sodium Stibogluconate Antimony. Br J Dermatol. 1988;119(1):53-7. PubMed PMID: 2841964.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Intralesional therapy of cutaneous leishmaniasis with sodium stibogluconate antimony. AU - Sharquie,K E, AU - Al-Talib,K K, AU - Chu,A C, PY - 1988/7/1/pubmed PY - 1988/7/1/medline PY - 1988/7/1/entrez SP - 53 EP - 7 JF - The British journal of dermatology JO - Br J Dermatol VL - 119 IS - 1 N2 - One hundred and thirty lesions of cutaneous leishmaniasis in 60 patients were treated with intralesional injections of Pentostam and 30 lesions were left untreated as controls. The injections were given at 8-day intervals and the patients followed-up for 42 days. One hundred and four lesions (80%) needed one injection only, 20 (15.4%) needed two and six (4.6%) needed three injections. One hundred and twenty three of the treated lesions (94.6%) showed a good clinical response with complete healing or marked improvement within the follow-up period. None of the control lesions showed marked improvement or complete healing. Scarring was minimal or absent following healing of treated lesions. The only side-effect was some localized pain following the injection. We recommend intralesional Pentostam as a safe and effective method of treating acute cutaneous leishmaniasis. SN - 0007-0963 UR - https://www.unboundmedicine.com/medline/citation/2841964/Intralesional_therapy_of_cutaneous_leishmaniasis_with_sodium_stibogluconate_antimony_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0007-0963&date=1988&volume=119&issue=1&spage=53 DB - PRIME DP - Unbound Medicine ER -