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Use of bronchoalveolar lavage in immunocompromised children with pneumonia.
Pediatr Pulmonol. 1988; 5(1):1-5.PP

Abstract

Because pneumonia in the immunocompromised host presents a diagnostic dilemma to the pediatrician, we prospectively studied the use of bronchoalveolar lavage (BAL) with flexible fiberoptic bronchoscopy in 14 immunocompromised children with pneumonia over a 5-month period. The children received immunosuppressive agents because of organ transplants, cancer, or systemic lupus erythematosus. A diagnosis was made by BAL in 10 (71%) of the 14 children. Pathogenic organisms included Pneumocystis carinii in six, cytomegalovirus (CMV) in two, Aspergillus fumigatus in one, and a mixed infection of Candida albicans and CMV in one. There were no complications. Because BAL by flexible fiber-optic bronchoscopy is a rapid and safe procedure and a diagnosis can be made in a majority of cases, we recommend its use in immunocompromised children with pneumonia before resorting to lung biopsy.

Authors+Show Affiliations

Pattishall EN
Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh, Pennsylvania 15213.
Noyes BE
No affiliation info available
Orenstein DM
No affiliation info available

MeSH

AdolescentBronchoalveolar Lavage FluidBronchoscopyChildChild, PreschoolCytomegalovirus InfectionsFemaleHumansImmune ToleranceInfantMaleOpportunistic InfectionsPneumoniaPneumonia, PneumocystisProspective Studies

Pub Type(s)

Journal Article

Language

eng

PubMed ID

2845341

Citation

Pattishall, E N., et al. "Use of Bronchoalveolar Lavage in Immunocompromised Children With Pneumonia." Pediatric Pulmonology, vol. 5, no. 1, 1988, pp. 1-5.
Pattishall EN, Noyes BE, Orenstein DM. Use of bronchoalveolar lavage in immunocompromised children with pneumonia. Pediatr Pulmonol. 1988;5(1):1-5.
Pattishall, E. N., Noyes, B. E., & Orenstein, D. M. (1988). Use of bronchoalveolar lavage in immunocompromised children with pneumonia. Pediatric Pulmonology, 5(1), 1-5.
Pattishall EN, Noyes BE, Orenstein DM. Use of Bronchoalveolar Lavage in Immunocompromised Children With Pneumonia. Pediatr Pulmonol. 1988;5(1):1-5. PubMed PMID: 2845341.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Use of bronchoalveolar lavage in immunocompromised children with pneumonia. AU - Pattishall,E N, AU - Noyes,B E, AU - Orenstein,D M, PY - 1988/1/1/pubmed PY - 1988/1/1/medline PY - 1988/1/1/entrez SP - 1 EP - 5 JF - Pediatric pulmonology JO - Pediatr Pulmonol VL - 5 IS - 1 N2 - Because pneumonia in the immunocompromised host presents a diagnostic dilemma to the pediatrician, we prospectively studied the use of bronchoalveolar lavage (BAL) with flexible fiberoptic bronchoscopy in 14 immunocompromised children with pneumonia over a 5-month period. The children received immunosuppressive agents because of organ transplants, cancer, or systemic lupus erythematosus. A diagnosis was made by BAL in 10 (71%) of the 14 children. Pathogenic organisms included Pneumocystis carinii in six, cytomegalovirus (CMV) in two, Aspergillus fumigatus in one, and a mixed infection of Candida albicans and CMV in one. There were no complications. Because BAL by flexible fiber-optic bronchoscopy is a rapid and safe procedure and a diagnosis can be made in a majority of cases, we recommend its use in immunocompromised children with pneumonia before resorting to lung biopsy. SN - 8755-6863 UR - https://www.unboundmedicine.com/medline/citation/2845341/Use_of_bronchoalveolar_lavage_in_immunocompromised_children_with_pneumonia_ DB - PRIME DP - Unbound Medicine ER -