Tags

Type your tag names separated by a space and hit enter

Dose-Response Effects of Long-Acting Liquid Methylphenidate in Children with Attention Deficit/Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD): A Pilot Study.
J Autism Dev Disord. 2017 08; 47(8):2307-2313.JA

Abstract

Attention deficit/hyperactivity disorder (ADHD) symptoms are common in youth with autism spectrum disorders (ASD) and are frequently treated with stimulant medications. Twenty-seven children were randomized to different dose titration schedules, and ADHD symptoms, tolerability, and aberrant behaviors were assessed weekly during a 6-week trial with long-acting liquid methylphenidate (MPH). MPH at low to moderate doses was effective in reducing ADHD symptoms and was well tolerated in young children with ASD and ADHD. Future studies are needed to assess generalization and maintenance of efficacy.

Authors+Show Affiliations

University of Washington, Seattle, WA, USA. Seattle Children's Research Institute, Seattle, WA, USA.Seattle Children's Research Institute, Seattle, WA, USA.University of Washington, Seattle, WA, USA.Seattle Children's Research Institute, Seattle, WA, USA.Seattle Children's Research Institute, Seattle, WA, USA.University of Washington, Seattle, WA, USA. Mark.stein@seattlechildrens.org. Seattle Children's Research Institute, Seattle, WA, USA. Mark.stein@seattlechildrens.org. Psychiatry, M/S OA.5.154, P. O. Box 5371, Seattle, WA, 98145-5005, USA. Mark.stein@seattlechildrens.org.

Pub Type(s)

Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

28474229

Citation

Kim, Soo-Jeong, et al. "Dose-Response Effects of Long-Acting Liquid Methylphenidate in Children With Attention Deficit/Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD): a Pilot Study." Journal of Autism and Developmental Disorders, vol. 47, no. 8, 2017, pp. 2307-2313.
Kim SJ, Shonka S, French WP, et al. Dose-Response Effects of Long-Acting Liquid Methylphenidate in Children with Attention Deficit/Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD): A Pilot Study. J Autism Dev Disord. 2017;47(8):2307-2313.
Kim, S. J., Shonka, S., French, W. P., Strickland, J., Miller, L., & Stein, M. A. (2017). Dose-Response Effects of Long-Acting Liquid Methylphenidate in Children with Attention Deficit/Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD): A Pilot Study. Journal of Autism and Developmental Disorders, 47(8), 2307-2313. https://doi.org/10.1007/s10803-017-3125-1
Kim SJ, et al. Dose-Response Effects of Long-Acting Liquid Methylphenidate in Children With Attention Deficit/Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD): a Pilot Study. J Autism Dev Disord. 2017;47(8):2307-2313. PubMed PMID: 28474229.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dose-Response Effects of Long-Acting Liquid Methylphenidate in Children with Attention Deficit/Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD): A Pilot Study. AU - Kim,Soo-Jeong, AU - Shonka,Sophia, AU - French,William P, AU - Strickland,Jennifer, AU - Miller,Lindsey, AU - Stein,Mark A, PY - 2017/5/6/pubmed PY - 2018/2/27/medline PY - 2017/5/6/entrez KW - ADHD KW - ASD KW - Attention deficit hyperactivity disorder KW - Autism spectrum disorder KW - Methylphenidate SP - 2307 EP - 2313 JF - Journal of autism and developmental disorders JO - J Autism Dev Disord VL - 47 IS - 8 N2 - Attention deficit/hyperactivity disorder (ADHD) symptoms are common in youth with autism spectrum disorders (ASD) and are frequently treated with stimulant medications. Twenty-seven children were randomized to different dose titration schedules, and ADHD symptoms, tolerability, and aberrant behaviors were assessed weekly during a 6-week trial with long-acting liquid methylphenidate (MPH). MPH at low to moderate doses was effective in reducing ADHD symptoms and was well tolerated in young children with ASD and ADHD. Future studies are needed to assess generalization and maintenance of efficacy. SN - 1573-3432 UR - https://www.unboundmedicine.com/medline/citation/28474229/Dose_Response_Effects_of_Long_Acting_Liquid_Methylphenidate_in_Children_with_Attention_Deficit/Hyperactivity_Disorder__ADHD__and_Autism_Spectrum_Disorder__ASD_:_A_Pilot_Study_ L2 - https://doi.org/10.1007/s10803-017-3125-1 DB - PRIME DP - Unbound Medicine ER -