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[Visceral leishmaniasis (kala-azar) in acquired immunodeficiency syndrome (AIDS)].
Dtsch Med Wochenschr. 1988 Dec 09; 113(49):1920-2.DM

Abstract

A 32-year-old homosexual with AIDS, who until 1985 was a frequent traveller to South America and mediterranean countries, had recurrent bouts of fever, splenomegaly, arthralgias as well as granulocytopenia and anaemia. Liver and bone-marrow punctures were performed to exclude malignant lymphoma and (or) a mycobacterial infection. Both biopsies revealed Leishmania donovani. During administration of sodium stibogluconate (Pentostam) the fever disappeared for a time and there was clinical improvement, but further treatment was limited because of thrombocytopenia. In patients with AIDS who have splenomegaly with nonspecific fever, visceral leishmaniasis must be considered in the differential diagnosis even outside of endemic regions.

Authors+Show Affiliations

Just G
Zentrum der Inneren Medizin, Universität Frankfurt/Main.
Simader R
No affiliation info available
Helm EB
No affiliation info available
Stille W
No affiliation info available
Falk S
No affiliation info available
Stutte HJ
No affiliation info available
Hübner K
No affiliation info available

MeSH

Acquired Immunodeficiency SyndromeAdultAntimony Sodium GluconateDiagnosis, DifferentialHumansLeishmaniasis, VisceralMaleSouth AmericaTravel

Pub Type(s)

Case Reports
English Abstract
Journal Article

Language

ger

PubMed ID

2848675

Citation

Just, G, et al. "[Visceral Leishmaniasis (kala-azar) in Acquired Immunodeficiency Syndrome (AIDS)]." Deutsche Medizinische Wochenschrift (1946), vol. 113, no. 49, 1988, pp. 1920-2.
Just G, Simader R, Helm EB, et al. [Visceral leishmaniasis (kala-azar) in acquired immunodeficiency syndrome (AIDS)]. Dtsch Med Wochenschr. 1988;113(49):1920-2.
Just, G., Simader, R., Helm, E. B., Stille, W., Falk, S., Stutte, H. J., & Hübner, K. (1988). [Visceral leishmaniasis (kala-azar) in acquired immunodeficiency syndrome (AIDS)]. Deutsche Medizinische Wochenschrift (1946), 113(49), 1920-2.
Just G, et al. [Visceral Leishmaniasis (kala-azar) in Acquired Immunodeficiency Syndrome (AIDS)]. Dtsch Med Wochenschr. 1988 Dec 9;113(49):1920-2. PubMed PMID: 2848675.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Visceral leishmaniasis (kala-azar) in acquired immunodeficiency syndrome (AIDS)]. AU - Just,G, AU - Simader,R, AU - Helm,E B, AU - Stille,W, AU - Falk,S, AU - Stutte,H J, AU - Hübner,K, PY - 1988/12/9/pubmed PY - 1988/12/9/medline PY - 1988/12/9/entrez SP - 1920 EP - 2 JF - Deutsche medizinische Wochenschrift (1946) JO - Dtsch Med Wochenschr VL - 113 IS - 49 N2 - A 32-year-old homosexual with AIDS, who until 1985 was a frequent traveller to South America and mediterranean countries, had recurrent bouts of fever, splenomegaly, arthralgias as well as granulocytopenia and anaemia. Liver and bone-marrow punctures were performed to exclude malignant lymphoma and (or) a mycobacterial infection. Both biopsies revealed Leishmania donovani. During administration of sodium stibogluconate (Pentostam) the fever disappeared for a time and there was clinical improvement, but further treatment was limited because of thrombocytopenia. In patients with AIDS who have splenomegaly with nonspecific fever, visceral leishmaniasis must be considered in the differential diagnosis even outside of endemic regions. SN - 0012-0472 UR - https://www.unboundmedicine.com/medline/citation/2848675/[Visceral_leishmaniasis__kala_azar__in_acquired_immunodeficiency_syndrome__AIDS_]_ DB - PRIME DP - Unbound Medicine ER -