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Hereditary Colorectal Cancer Syndromes.
Surg Clin North Am. 2017 Jun; 97(3):605-625.SC

Abstract

Awareness of hereditary colorectal cancer syndromes is important to facilitate their identification because affected patients are at increased risk for early onset, synchronous, and metachronous colorectal malignancies, and certain extracolonic malignancies depending on the syndrome. Identification of an affected individual allows for screening and early interventions for patients and their at-risk kindred. Genetic counseling and testing is important to the care of these patients. As knowledge of the genetic basis of these syndromes grows, unique genotype-phenotype profiles allow clinicians to tailor surveillance and treatment strategies based on individual risk.

Authors+Show Affiliations

Department of Surgery, Division of Colon and Rectal Surgery, Baylor University Medical Center, 3409 Worth Street, Suite 640, Dallas, TX 75246, USA.Division of General Surgery, Section of Colon and Rectal Surgery, Washington University Inherited Colorectal Cancer and Polyposis Registry, Washington University General Surgery Residency, Washington University in St Louis School of Medicine, 660 South Euclid Avenue, Campus Box 8109, St Louis, MO 63110, USA. Electronic address: wisep@wustl.edu.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

28501250

Citation

Wells, Katerina, and Paul E. Wise. "Hereditary Colorectal Cancer Syndromes." The Surgical Clinics of North America, vol. 97, no. 3, 2017, pp. 605-625.
Wells K, Wise PE. Hereditary Colorectal Cancer Syndromes. Surg Clin North Am. 2017;97(3):605-625.
Wells, K., & Wise, P. E. (2017). Hereditary Colorectal Cancer Syndromes. The Surgical Clinics of North America, 97(3), 605-625. https://doi.org/10.1016/j.suc.2017.01.009
Wells K, Wise PE. Hereditary Colorectal Cancer Syndromes. Surg Clin North Am. 2017;97(3):605-625. PubMed PMID: 28501250.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Hereditary Colorectal Cancer Syndromes. AU - Wells,Katerina, AU - Wise,Paul E, PY - 2017/5/15/entrez PY - 2017/5/16/pubmed PY - 2017/7/18/medline KW - Familial adenomatous polyposis KW - Hereditary nonpolyposis colorectal cancer KW - Inherited colon cancer KW - Lynch syndrome KW - MUTYH-associated polyposis KW - Serrated polyposis syndrome SP - 605 EP - 625 JF - The Surgical clinics of North America JO - Surg Clin North Am VL - 97 IS - 3 N2 - Awareness of hereditary colorectal cancer syndromes is important to facilitate their identification because affected patients are at increased risk for early onset, synchronous, and metachronous colorectal malignancies, and certain extracolonic malignancies depending on the syndrome. Identification of an affected individual allows for screening and early interventions for patients and their at-risk kindred. Genetic counseling and testing is important to the care of these patients. As knowledge of the genetic basis of these syndromes grows, unique genotype-phenotype profiles allow clinicians to tailor surveillance and treatment strategies based on individual risk. SN - 1558-3171 UR - https://www.unboundmedicine.com/medline/citation/28501250/Hereditary_Colorectal_Cancer_Syndromes_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0039-6109(17)30009-9 DB - PRIME DP - Unbound Medicine ER -