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Monitoring the elimination of human African trypanosomiasis: Update to 2014.
PLoS Negl Trop Dis. 2017 May; 11(5):e0005585.PN

Abstract

BACKGROUND

The World Health Organization (WHO) has targeted the elimination of Human African trypanosomiasis (HAT) 'as a public health problem' by 2020. The selected indicators of elimination should be monitored every two years, and we provide here a comprehensive update to 2014. The monitoring system is underpinned by the Atlas of HAT.

RESULTS

With 3,797 reported cases in 2014, the corresponding milestone (5,000 cases) was surpassed, and the 2020 global target of 'fewer than 2,000 reported cases per year' seems within reach. The areas where HAT is still a public health problem (i.e. > 1 HAT reported case per 10,000 people per year) have halved in less than a decade, and in 2014 they corresponded to 350 thousand km2. The number and potential coverage of fixed health facilities offering diagnosis and treatment for HAT has expanded, and approximately 1,000 are now operating in 23 endemic countries. The observed trends are supported by sustained surveillance and improved reporting.

DISCUSSION

HAT elimination appears to be on track. For gambiense HAT, still accounting for the vast majority of reported cases, progress continues unabated in a context of sustained intensity of screening activities. For rhodesiense HAT, a slow-down was observed in the last few years. Looking beyond the 2020 target, innovative tools and approaches will be increasingly needed. Coordination, through the WHO network for HAT elimination, will remain crucial to overcome the foreseeable and unforeseeable challenges that an elimination process will inevitably pose.

Authors+Show Affiliations

World Health Organization, Control of Neglected Tropical Diseases, Innovative and Intensified Disease Management, Geneva, Switzerland.Food and Agriculture Organization of the United Nations, Sub-regional Office for Eastern Africa, Addis Ababa, Ethiopia.World Health Organization, Control of Neglected Tropical Diseases, Innovative and Intensified Disease Management, Geneva, Switzerland.Food and Agriculture Organization of the United Nations, Animal Production and Health Division, Rome, Italy.World Health Organization, Regional Office for Africa, Communicable Disease Unit, Brazzaville, Congo.World Health Organization, Control of Neglected Tropical Diseases, Innovative and Intensified Disease Management, Geneva, Switzerland.Food and Agriculture Organization of the United Nations, Animal Production and Health Division, Rome, Italy.World Health Organization, Control of Neglected Tropical Diseases, Innovative and Intensified Disease Management, Geneva, Switzerland.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

28531222

Citation

Franco, José R., et al. "Monitoring the Elimination of Human African Trypanosomiasis: Update to 2014." PLoS Neglected Tropical Diseases, vol. 11, no. 5, 2017, pp. e0005585.
Franco JR, Cecchi G, Priotto G, et al. Monitoring the elimination of human African trypanosomiasis: Update to 2014. PLoS Negl Trop Dis. 2017;11(5):e0005585.
Franco, J. R., Cecchi, G., Priotto, G., Paone, M., Diarra, A., Grout, L., Mattioli, R. C., & Argaw, D. (2017). Monitoring the elimination of human African trypanosomiasis: Update to 2014. PLoS Neglected Tropical Diseases, 11(5), e0005585. https://doi.org/10.1371/journal.pntd.0005585
Franco JR, et al. Monitoring the Elimination of Human African Trypanosomiasis: Update to 2014. PLoS Negl Trop Dis. 2017;11(5):e0005585. PubMed PMID: 28531222.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Monitoring the elimination of human African trypanosomiasis: Update to 2014. AU - Franco,José R, AU - Cecchi,Giuliano, AU - Priotto,Gerardo, AU - Paone,Massimo, AU - Diarra,Abdoulaye, AU - Grout,Lise, AU - Mattioli,Raffaele C, AU - Argaw,Daniel, Y1 - 2017/05/22/ PY - 2017/01/01/received PY - 2017/04/20/accepted PY - 2017/06/02/revised PY - 2017/5/23/pubmed PY - 2017/7/14/medline PY - 2017/5/23/entrez SP - e0005585 EP - e0005585 JF - PLoS neglected tropical diseases JO - PLoS Negl Trop Dis VL - 11 IS - 5 N2 - BACKGROUND: The World Health Organization (WHO) has targeted the elimination of Human African trypanosomiasis (HAT) 'as a public health problem' by 2020. The selected indicators of elimination should be monitored every two years, and we provide here a comprehensive update to 2014. The monitoring system is underpinned by the Atlas of HAT. RESULTS: With 3,797 reported cases in 2014, the corresponding milestone (5,000 cases) was surpassed, and the 2020 global target of 'fewer than 2,000 reported cases per year' seems within reach. The areas where HAT is still a public health problem (i.e. > 1 HAT reported case per 10,000 people per year) have halved in less than a decade, and in 2014 they corresponded to 350 thousand km2. The number and potential coverage of fixed health facilities offering diagnosis and treatment for HAT has expanded, and approximately 1,000 are now operating in 23 endemic countries. The observed trends are supported by sustained surveillance and improved reporting. DISCUSSION: HAT elimination appears to be on track. For gambiense HAT, still accounting for the vast majority of reported cases, progress continues unabated in a context of sustained intensity of screening activities. For rhodesiense HAT, a slow-down was observed in the last few years. Looking beyond the 2020 target, innovative tools and approaches will be increasingly needed. Coordination, through the WHO network for HAT elimination, will remain crucial to overcome the foreseeable and unforeseeable challenges that an elimination process will inevitably pose. SN - 1935-2735 UR - https://www.unboundmedicine.com/medline/citation/28531222/full_citation L2 - http://dx.plos.org/10.1371/journal.pntd.0005585 DB - PRIME DP - Unbound Medicine ER -