TY - JOUR T1 - Acute nutritional axonal neuropathy. AU - Hamel,Johanna, AU - Logigian,Eric L, Y1 - 2017/06/19/ PY - 2017/01/14/received PY - 2017/05/21/revised PY - 2017/05/23/accepted PY - 2017/5/31/pubmed PY - 2017/12/13/medline PY - 2017/5/31/entrez KW - Guillain-Barre syndrome KW - alcohol KW - neuropathic pain KW - nutritional KW - peripheral neuropathy SP - 33 EP - 39 JF - Muscle & nerve JO - Muscle Nerve VL - 57 IS - 1 N2 - INTRODUCTION: This study describes clinical, laboratory, and electrodiagnostic features of a severe acute axonal polyneuropathy common to patients with acute nutritional deficiency in the setting of alcoholism, bariatric surgery (BS), or anorexia. METHODS: Retrospective analysis of clinical, electrodiagnostic, and laboratory data of patients with acute axonal neuropathy. RESULTS: Thirteen patients were identified with a severe, painful, sensory or sensorimotor axonal polyneuropathy that developed over 2-12 weeks with sensory ataxia, areflexia, variable muscle weakness, poor nutritional status, and weight loss, often with prolonged vomiting and normal cerebrospinal fluid protein. Vitamin B6 was low in half and thiamine was low in all patients when obtained before supplementation. Patients improved with weight gain and vitamin supplementation, with motor greater than sensory recovery. DISCUSSION: We suggest that acute or subacute axonal neuropathy in patients with weight loss or vomiting associated with alcohol abuse, BS, or dietary deficiency is one syndrome, caused by micronutrient deficiencies. Muscle Nerve 57: 33-39, 2018. SN - 1097-4598 UR - https://www.unboundmedicine.com/medline/citation/28556429/Acute_nutritional_axonal_neuropathy_ L2 - https://doi.org/10.1002/mus.25702 DB - PRIME DP - Unbound Medicine ER -