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A comparison of sodium hypochlorite and sodium dichloroisocyanurate products.
J Hosp Infect. 1985 Mar; 6(1):31-40.JH

Abstract

A comparison of commercial sodium hypochlorite (NaOCl) and sodium dichloroisocyanurate (NaDCC) products was made. Solutions of NaOCl and NaDCC containing the same levels of available chlorine (av.Cl) exhibited very similar bactericidal activities, despite significant differences in pH. A level of 12.5 ppm av. Cl achieved a greater than 5 log 10 reduction of Staphylococcus aureus in 2 min. A level of 5 ppm av.Cl achieved a greater than 5 log 10 reduction of Pseudomonas aeruginosa in 2 min whilst approximately 100 ppm av.Cl achieved the same reduction in the presence of 1% horse serum, and approximately 200 ppm av.Cl in the presence of 2% horse serum, indicating inactivation levels of around 95 and 97.5% respectively. Tablets of NaDCC were stable but solutions were unstable and decomposed much faster than NaOCl solutions of the same strength. Batch-to-batch variability of different NaOCl and NaDCC products was investigated; whilst NaDCC products always contained the minimum level of av.Cl specified, concentrated NaOCl products sometimes did not due to inherent instability.

Authors

Coates D
No affiliation info available

MeSH

DisinfectantsDrug StabilityMicrobial Sensitivity TestsPseudomonas aeruginosaSodium HypochloriteSolutionsStaphylococcus aureusTabletsTriazines

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

2859320

Citation

Coates, D. "A Comparison of Sodium Hypochlorite and Sodium Dichloroisocyanurate Products." The Journal of Hospital Infection, vol. 6, no. 1, 1985, pp. 31-40.
Coates D. A comparison of sodium hypochlorite and sodium dichloroisocyanurate products. J Hosp Infect. 1985;6(1):31-40.
Coates, D. (1985). A comparison of sodium hypochlorite and sodium dichloroisocyanurate products. The Journal of Hospital Infection, 6(1), 31-40.
Coates D. A Comparison of Sodium Hypochlorite and Sodium Dichloroisocyanurate Products. J Hosp Infect. 1985;6(1):31-40. PubMed PMID: 2859320.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A comparison of sodium hypochlorite and sodium dichloroisocyanurate products. A1 - Coates,D, PY - 1985/3/1/pubmed PY - 1985/3/1/medline PY - 1985/3/1/entrez SP - 31 EP - 40 JF - The Journal of hospital infection JO - J Hosp Infect VL - 6 IS - 1 N2 - A comparison of commercial sodium hypochlorite (NaOCl) and sodium dichloroisocyanurate (NaDCC) products was made. Solutions of NaOCl and NaDCC containing the same levels of available chlorine (av.Cl) exhibited very similar bactericidal activities, despite significant differences in pH. A level of 12.5 ppm av. Cl achieved a greater than 5 log 10 reduction of Staphylococcus aureus in 2 min. A level of 5 ppm av.Cl achieved a greater than 5 log 10 reduction of Pseudomonas aeruginosa in 2 min whilst approximately 100 ppm av.Cl achieved the same reduction in the presence of 1% horse serum, and approximately 200 ppm av.Cl in the presence of 2% horse serum, indicating inactivation levels of around 95 and 97.5% respectively. Tablets of NaDCC were stable but solutions were unstable and decomposed much faster than NaOCl solutions of the same strength. Batch-to-batch variability of different NaOCl and NaDCC products was investigated; whilst NaDCC products always contained the minimum level of av.Cl specified, concentrated NaOCl products sometimes did not due to inherent instability. SN - 0195-6701 UR - https://www.unboundmedicine.com/medline/citation/2859320/A_comparison_of_sodium_hypochlorite_and_sodium_dichloroisocyanurate_products_ DB - PRIME DP - Unbound Medicine ER -