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Informant-Reported Cognitive Decline and Activity Engagement across Four Years in a Community Sample.
Gerontology 2017; 63(5):469-478G

Abstract

BACKGROUND

Subtle age-related cognitive decline may be associated with the capacity to remain engaged in mental, physical, and social activities. Informant reports of cognitive decline potentially provide additional information to psychometric tests on change in everyday cognitive function relevant to activity engagement.

OBJECTIVE

To investigate relations between decline in everyday cognitive function as assessed by informant report and activity engagement in community-dwelling older adults.

METHODS

A sample of cognitively normal older adults was drawn from the 2 latest waves of the PATH Through Life Study (n = 1,391; mean age 74.5 ± 1.5, 48.4% female). PATH is a 16-year longitudinal cohort study set in the Canberra/Queanbeyan district, Australia. Assessments were carried out at baseline, and at 3 subsequent time-points 4 years apart. At wave-4, the IQCODE, an informant measure of 4-year cognitive decline was provided by a spouse, family member, or friend of each participant. Activity engagement was assessed by the abbreviated RIASEC Mental Activity List, self-reported frequency and duration of physical activity (Whitehall Questionnaire) and the Lubben Social Network Scale that assessed interaction with family/friends. Participants provided demographic information, self-reported health status (SF-12), and responses to the Goldberg Depression Scale. The Symbol Digit Modalities Test (SDMT) and California Verbal Learning Test (CVLT) were used to measure objective 4-year cognitive change. Those with MMSE score of ≤27 were excluded.

RESULTS

IQCODE score predicted disengagement from mental activities over 4 years in cognitively healthy adults (β = -0.056, standard error [SE] = 0.019, p = 0.004). This association was robust to covariate control and change on the SDMT which was also significantly related to mental activity disengagement. In models adjusted for change scores on the SDMT and the CVLT, the IQCODE was associated with less physical (β = -0.692, SE = 0.24, p = 0.004) and social engagement (β -0.046, SE = 0.021, p = 0.032), but relationships were attenuated with the inclusion of covariates.

CONCLUSION

Informant-reported cognitive decline in a non-clinical sample was linked to activities that support cognitive health. Associations were robust to adjustment for cognitive change scores. Utilising informant reports prior to the manifestation of clinically relevant decline may identify those who would benefit most from personalised activity interventions.

Authors+Show Affiliations

Centre for Research on Ageing Health and Wellbeing, The Australian National University, Canberra, ACT, Australia.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

28595181

Citation

Hosking, Diane E., et al. "Informant-Reported Cognitive Decline and Activity Engagement Across Four Years in a Community Sample." Gerontology, vol. 63, no. 5, 2017, pp. 469-478.
Hosking DE, Jiang D, Sargent-Cox KA, et al. Informant-Reported Cognitive Decline and Activity Engagement across Four Years in a Community Sample. Gerontology. 2017;63(5):469-478.
Hosking, D. E., Jiang, D., Sargent-Cox, K. A., & Anstey, K. J. (2017). Informant-Reported Cognitive Decline and Activity Engagement across Four Years in a Community Sample. Gerontology, 63(5), pp. 469-478. doi:10.1159/000475594.
Hosking DE, et al. Informant-Reported Cognitive Decline and Activity Engagement Across Four Years in a Community Sample. Gerontology. 2017;63(5):469-478. PubMed PMID: 28595181.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Informant-Reported Cognitive Decline and Activity Engagement across Four Years in a Community Sample. AU - Hosking,Diane E, AU - Jiang,Da, AU - Sargent-Cox,Kerry A, AU - Anstey,Kaarin J, Y1 - 2017/06/09/ PY - 2016/10/04/received PY - 2017/04/09/accepted PY - 2017/6/9/pubmed PY - 2018/5/10/medline PY - 2017/6/9/entrez KW - Cognitive decline KW - Engagement KW - Informant reports KW - Lifestyle activities SP - 469 EP - 478 JF - Gerontology JO - Gerontology VL - 63 IS - 5 N2 - BACKGROUND: Subtle age-related cognitive decline may be associated with the capacity to remain engaged in mental, physical, and social activities. Informant reports of cognitive decline potentially provide additional information to psychometric tests on change in everyday cognitive function relevant to activity engagement. OBJECTIVE: To investigate relations between decline in everyday cognitive function as assessed by informant report and activity engagement in community-dwelling older adults. METHODS: A sample of cognitively normal older adults was drawn from the 2 latest waves of the PATH Through Life Study (n = 1,391; mean age 74.5 ± 1.5, 48.4% female). PATH is a 16-year longitudinal cohort study set in the Canberra/Queanbeyan district, Australia. Assessments were carried out at baseline, and at 3 subsequent time-points 4 years apart. At wave-4, the IQCODE, an informant measure of 4-year cognitive decline was provided by a spouse, family member, or friend of each participant. Activity engagement was assessed by the abbreviated RIASEC Mental Activity List, self-reported frequency and duration of physical activity (Whitehall Questionnaire) and the Lubben Social Network Scale that assessed interaction with family/friends. Participants provided demographic information, self-reported health status (SF-12), and responses to the Goldberg Depression Scale. The Symbol Digit Modalities Test (SDMT) and California Verbal Learning Test (CVLT) were used to measure objective 4-year cognitive change. Those with MMSE score of ≤27 were excluded. RESULTS: IQCODE score predicted disengagement from mental activities over 4 years in cognitively healthy adults (β = -0.056, standard error [SE] = 0.019, p = 0.004). This association was robust to covariate control and change on the SDMT which was also significantly related to mental activity disengagement. In models adjusted for change scores on the SDMT and the CVLT, the IQCODE was associated with less physical (β = -0.692, SE = 0.24, p = 0.004) and social engagement (β -0.046, SE = 0.021, p = 0.032), but relationships were attenuated with the inclusion of covariates. CONCLUSION: Informant-reported cognitive decline in a non-clinical sample was linked to activities that support cognitive health. Associations were robust to adjustment for cognitive change scores. Utilising informant reports prior to the manifestation of clinically relevant decline may identify those who would benefit most from personalised activity interventions. SN - 1423-0003 UR - https://www.unboundmedicine.com/medline/citation/28595181/Informant_Reported_Cognitive_Decline_and_Activity_Engagement_across_Four_Years_in_a_Community_Sample_ L2 - https://www.karger.com?DOI=10.1159/000475594 DB - PRIME DP - Unbound Medicine ER -