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Report of Increasing Overdose Deaths that include Acetyl Fentanyl in Multiple Counties of the Southwestern Region of the Commonwealth of Pennsylvania in 2015-2016.
J Forensic Sci 2018; 63(1):195-200JF

Abstract

Acetyl fentanyl is a Schedule I controlled synthetic opioid that is becoming an increasingly detected "designer drug." Routine drug screening procedures in local forensic toxicology laboratories identified a total of 41 overdose deaths associated with acetyl fentanyl within multiple counties of the southwestern region of the state of Pennsylvania. The range, median, mean, and standard deviation of blood acetyl fentanyl concentrations for these 41 cases were 0.13-2100 ng/mL, 11 ng/mL, 169.3 ng/mL, and 405.3 ng/mL, respectively. Thirty-six individuals (88%) had a confirmed history of substance abuse, and all but one case (96%) were ruled multiple drug toxicities. This report characterizes this localized trend of overdose deaths associated with acetyl fentanyl and provides further evidence supporting an alarmingly concentrated opiate and opioid epidemic of both traditional and novel drugs within this region of the United States.

Authors+Show Affiliations

Allegheny County Office of the Medical Examiner, 1520 Penn Avenue, Pittsburgh, PA, 15222.Allegheny County Office of the Medical Examiner, 1520 Penn Avenue, Pittsburgh, PA, 15222.Allegheny County Office of the Medical Examiner, 1520 Penn Avenue, Pittsburgh, PA, 15222.Allegheny County Office of the Medical Examiner, 1520 Penn Avenue, Pittsburgh, PA, 15222.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

28605020

Citation

Dwyer, Jessica B., et al. "Report of Increasing Overdose Deaths That Include Acetyl Fentanyl in Multiple Counties of the Southwestern Region of the Commonwealth of Pennsylvania in 2015-2016." Journal of Forensic Sciences, vol. 63, no. 1, 2018, pp. 195-200.
Dwyer JB, Janssen J, Luckasevic TM, et al. Report of Increasing Overdose Deaths that include Acetyl Fentanyl in Multiple Counties of the Southwestern Region of the Commonwealth of Pennsylvania in 2015-2016. J Forensic Sci. 2018;63(1):195-200.
Dwyer, J. B., Janssen, J., Luckasevic, T. M., & Williams, K. E. (2018). Report of Increasing Overdose Deaths that include Acetyl Fentanyl in Multiple Counties of the Southwestern Region of the Commonwealth of Pennsylvania in 2015-2016. Journal of Forensic Sciences, 63(1), pp. 195-200. doi:10.1111/1556-4029.13517.
Dwyer JB, et al. Report of Increasing Overdose Deaths That Include Acetyl Fentanyl in Multiple Counties of the Southwestern Region of the Commonwealth of Pennsylvania in 2015-2016. J Forensic Sci. 2018;63(1):195-200. PubMed PMID: 28605020.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Report of Increasing Overdose Deaths that include Acetyl Fentanyl in Multiple Counties of the Southwestern Region of the Commonwealth of Pennsylvania in 2015-2016. AU - Dwyer,Jessica B, AU - Janssen,Jennifer, AU - Luckasevic,Todd M, AU - Williams,Karl E, Y1 - 2017/06/12/ PY - 2016/11/24/received PY - 2017/03/10/revised PY - 2017/03/13/accepted PY - 2017/6/13/pubmed PY - 2018/4/24/medline PY - 2017/6/13/entrez KW - acetyl fentanyl KW - fentanyl KW - forensic science KW - forensic toxicology KW - overdose KW - postmortem KW - synthetic opioids SP - 195 EP - 200 JF - Journal of forensic sciences JO - J. Forensic Sci. VL - 63 IS - 1 N2 - Acetyl fentanyl is a Schedule I controlled synthetic opioid that is becoming an increasingly detected "designer drug." Routine drug screening procedures in local forensic toxicology laboratories identified a total of 41 overdose deaths associated with acetyl fentanyl within multiple counties of the southwestern region of the state of Pennsylvania. The range, median, mean, and standard deviation of blood acetyl fentanyl concentrations for these 41 cases were 0.13-2100 ng/mL, 11 ng/mL, 169.3 ng/mL, and 405.3 ng/mL, respectively. Thirty-six individuals (88%) had a confirmed history of substance abuse, and all but one case (96%) were ruled multiple drug toxicities. This report characterizes this localized trend of overdose deaths associated with acetyl fentanyl and provides further evidence supporting an alarmingly concentrated opiate and opioid epidemic of both traditional and novel drugs within this region of the United States. SN - 1556-4029 UR - https://www.unboundmedicine.com/medline/citation/28605020/Report_of_Increasing_Overdose_Deaths_that_include_Acetyl_Fentanyl_in_Multiple_Counties_of_the_Southwestern_Region_of_the_Commonwealth_of_Pennsylvania_in_2015-2016 L2 - https://doi.org/10.1111/1556-4029.13517 DB - PRIME DP - Unbound Medicine ER -