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SAMPUS, MELTUMP and THIMUMP - Diagnostic Categories Characterized by Uncertain Biological Behavior.
Klin Onkol Summer 2017; 30(3):221-223KO

Abstract

In the dermatopathological practice, there is a group of atypical melanocytic lesions with borderline histological features between benign simulants and malignant melanoma (MM), due to conflicting diagnostic criteria and inter-observer disagreement. In these cases, the dermatopathologist is authorized to seek consult with an established expert in the field, but even the most experienced specialist may not be sure about the correct diagnosis and the subsequent biological behavior. There is general consensus among qualified dermatopathologists that can be helpful to insert these ambiguous cases into two diagnostic categories: SAMPUS (Superficial Atypical Melanocytic Proliferations of Unknown Significance) and MELTUMP (MELanocytic Tumors of Uncertain Malignant Potential). According to the conception of MM progression through two phases, the radial growth phase and the vertical growth phase, it is possible to identify a novel subtype of thin melanoma (THIM) with uncertain metastatic potential, due to the presence of extensive regression (75% of the lesion volume), which we here define with the acronym THIMUMP (THIn Melanoma of Uncertain Metastatic Potential) for the first time in literature.Key words: malignant melanoma - thin melanoma - histology.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

28612620

Citation

Roncati, L, et al. "SAMPUS, MELTUMP and THIMUMP - Diagnostic Categories Characterized By Uncertain Biological Behavior." Klinicka Onkologie : Casopis Ceske a Slovenske Onkologicke Spolecnosti, vol. 30, no. 3, 2017, pp. 221-223.
Roncati L, Piscioli F, Pusiol T. SAMPUS, MELTUMP and THIMUMP - Diagnostic Categories Characterized by Uncertain Biological Behavior. Klin Onkol. 2017;30(3):221-223.
Roncati, L., Piscioli, F., & Pusiol, T. (2017). SAMPUS, MELTUMP and THIMUMP - Diagnostic Categories Characterized by Uncertain Biological Behavior. Klinicka Onkologie : Casopis Ceske a Slovenske Onkologicke Spolecnosti, 30(3), pp. 221-223. doi:10.14735/amko2017221.
Roncati L, Piscioli F, Pusiol T. SAMPUS, MELTUMP and THIMUMP - Diagnostic Categories Characterized By Uncertain Biological Behavior. Klin Onkol. 2017;30(3):221-223. PubMed PMID: 28612620.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - SAMPUS, MELTUMP and THIMUMP - Diagnostic Categories Characterized by Uncertain Biological Behavior. AU - Roncati,L, AU - Piscioli,F, AU - Pusiol,T, PY - 2017/6/15/entrez PY - 2017/6/15/pubmed PY - 2017/9/7/medline SP - 221 EP - 223 JF - Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti JO - Klin Onkol VL - 30 IS - 3 N2 - In the dermatopathological practice, there is a group of atypical melanocytic lesions with borderline histological features between benign simulants and malignant melanoma (MM), due to conflicting diagnostic criteria and inter-observer disagreement. In these cases, the dermatopathologist is authorized to seek consult with an established expert in the field, but even the most experienced specialist may not be sure about the correct diagnosis and the subsequent biological behavior. There is general consensus among qualified dermatopathologists that can be helpful to insert these ambiguous cases into two diagnostic categories: SAMPUS (Superficial Atypical Melanocytic Proliferations of Unknown Significance) and MELTUMP (MELanocytic Tumors of Uncertain Malignant Potential). According to the conception of MM progression through two phases, the radial growth phase and the vertical growth phase, it is possible to identify a novel subtype of thin melanoma (THIM) with uncertain metastatic potential, due to the presence of extensive regression (75% of the lesion volume), which we here define with the acronym THIMUMP (THIn Melanoma of Uncertain Metastatic Potential) for the first time in literature.Key words: malignant melanoma - thin melanoma - histology. SN - 0862-495X UR - https://www.unboundmedicine.com/medline/citation/28612620/SAMPUS_MELTUMP_and_THIMUMP___Diagnostic_Categories_Characterized_by_Uncertain_Biological_Behavior_ L2 - https://www.prolekare.cz/linkout/61116 DB - PRIME DP - Unbound Medicine ER -