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Laryngotracheal Involvement in Systemic Light Chain Amyloidosis.
Head Neck Pathol. 2018 Mar; 12(1):127-130.HN

Abstract

Laryngotracheal amyloid deposition is an uncommon manifestation of systemic light chain amyloidosis. Diagnostic imaging, such as CT, is useful for suggesting the possibility of amyloidosis and delineating the extent of the lesions for surgical management; however, the diagnosis is confirmed with the histologic finding of amorphous eosinophilic material which stains positively for Congo red and may show apple green birefringence on polarization. These features are exemplified in this sine qua non radiology-pathology correlation article.

Authors+Show Affiliations

Department of Radiology, University of Chicago, 5841 S Maryland Avenue, Chicago, IL, 60637, USA. dtg1@uchicago.edu.Department of Pathology, University of Chicago, Chicago, IL, USA.Department of Surgery, Section of Otolaryngology, University of Chicago, Chicago, IL, USA.Department of Pathology, University of Chicago, Chicago, IL, USA.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

28616786

Citation

Ginat, Daniel T., et al. "Laryngotracheal Involvement in Systemic Light Chain Amyloidosis." Head and Neck Pathology, vol. 12, no. 1, 2018, pp. 127-130.
Ginat DT, Schulte J, Portugal L, et al. Laryngotracheal Involvement in Systemic Light Chain Amyloidosis. Head Neck Pathol. 2018;12(1):127-130.
Ginat, D. T., Schulte, J., Portugal, L., & Cipriani, N. A. (2018). Laryngotracheal Involvement in Systemic Light Chain Amyloidosis. Head and Neck Pathology, 12(1), 127-130. https://doi.org/10.1007/s12105-017-0831-0
Ginat DT, et al. Laryngotracheal Involvement in Systemic Light Chain Amyloidosis. Head Neck Pathol. 2018;12(1):127-130. PubMed PMID: 28616786.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Laryngotracheal Involvement in Systemic Light Chain Amyloidosis. AU - Ginat,Daniel T, AU - Schulte,Jefree, AU - Portugal,Louis, AU - Cipriani,Nicole A, Y1 - 2017/06/14/ PY - 2017/05/17/received PY - 2017/06/10/accepted PY - 2017/6/16/pubmed PY - 2018/9/1/medline PY - 2017/6/16/entrez KW - Amyloidoma KW - Amyloidosis KW - Larynx KW - Pathology KW - Radiology KW - Trachea SP - 127 EP - 130 JF - Head and neck pathology JO - Head Neck Pathol VL - 12 IS - 1 N2 - Laryngotracheal amyloid deposition is an uncommon manifestation of systemic light chain amyloidosis. Diagnostic imaging, such as CT, is useful for suggesting the possibility of amyloidosis and delineating the extent of the lesions for surgical management; however, the diagnosis is confirmed with the histologic finding of amorphous eosinophilic material which stains positively for Congo red and may show apple green birefringence on polarization. These features are exemplified in this sine qua non radiology-pathology correlation article. SN - 1936-0568 UR - https://www.unboundmedicine.com/medline/citation/28616786/Laryngotracheal_Involvement_in_Systemic_Light_Chain_Amyloidosis_ L2 - https://dx.doi.org/10.1007/s12105-017-0831-0 DB - PRIME DP - Unbound Medicine ER -