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Phylogeography of Burkholderia pseudomallei Isolates, Western Hemisphere.
Emerg Infect Dis. 2017 07; 23(7):1133-1138.EI

Abstract

The bacterium Burkholderia pseudomallei causes melioidosis, which is mainly associated with tropical areas. We analyzed single-nucleotide polymorphisms (SNPs) among genome sequences from isolates of B. pseudomallei that originated in the Western Hemisphere by comparing them with genome sequences of isolates that originated in the Eastern Hemisphere. Analysis indicated that isolates from the Western Hemisphere form a distinct clade, which supports the hypothesis that these isolates were derived from a constricted seeding event from Africa. Subclades have been resolved that are associated with specific regions within the Western Hemisphere and suggest that isolates might be correlated geographically with cases of melioidosis. One isolate associated with a former World War II prisoner of war was believed to represent illness 62 years after exposure in Southeast Asia. However, analysis suggested the isolate originated in Central or South America.

Authors

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Pub Type(s)

Journal Article

Language

eng

PubMed ID

28628442

Citation

Gee, Jay E., et al. "Phylogeography of Burkholderia Pseudomallei Isolates, Western Hemisphere." Emerging Infectious Diseases, vol. 23, no. 7, 2017, pp. 1133-1138.
Gee JE, Gulvik CA, Elrod MG, et al. Phylogeography of Burkholderia pseudomallei Isolates, Western Hemisphere. Emerging Infect Dis. 2017;23(7):1133-1138.
Gee, J. E., Gulvik, C. A., Elrod, M. G., Batra, D., Rowe, L. A., Sheth, M., & Hoffmaster, A. R. (2017). Phylogeography of Burkholderia pseudomallei Isolates, Western Hemisphere. Emerging Infectious Diseases, 23(7), 1133-1138. https://doi.org/10.3201/eid2307.161978
Gee JE, et al. Phylogeography of Burkholderia Pseudomallei Isolates, Western Hemisphere. Emerging Infect Dis. 2017;23(7):1133-1138. PubMed PMID: 28628442.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Phylogeography of Burkholderia pseudomallei Isolates, Western Hemisphere. AU - Gee,Jay E, AU - Gulvik,Christopher A, AU - Elrod,Mindy G, AU - Batra,Dhwani, AU - Rowe,Lori A, AU - Sheth,Mili, AU - Hoffmaster,Alex R, PY - 2017/6/20/entrez PY - 2017/6/20/pubmed PY - 2018/3/27/medline KW - Americas KW - Burkholderia pseudomallei KW - Mexico KW - Puerto Rico KW - SNPs KW - Trinidad KW - United States KW - Western Hemisphere KW - bacteria KW - genome KW - melioidosis KW - phylogeography KW - single-nucleotide polymorphisms SP - 1133 EP - 1138 JF - Emerging infectious diseases JO - Emerging Infect. Dis. VL - 23 IS - 7 N2 - The bacterium Burkholderia pseudomallei causes melioidosis, which is mainly associated with tropical areas. We analyzed single-nucleotide polymorphisms (SNPs) among genome sequences from isolates of B. pseudomallei that originated in the Western Hemisphere by comparing them with genome sequences of isolates that originated in the Eastern Hemisphere. Analysis indicated that isolates from the Western Hemisphere form a distinct clade, which supports the hypothesis that these isolates were derived from a constricted seeding event from Africa. Subclades have been resolved that are associated with specific regions within the Western Hemisphere and suggest that isolates might be correlated geographically with cases of melioidosis. One isolate associated with a former World War II prisoner of war was believed to represent illness 62 years after exposure in Southeast Asia. However, analysis suggested the isolate originated in Central or South America. SN - 1080-6059 UR - https://www.unboundmedicine.com/medline/citation/28628442/Phylogeography_of_Burkholderia_pseudomallei_Isolates_Western_Hemisphere_ L2 - https://dx.doi.org/10.3201/eid2307.161978 DB - PRIME DP - Unbound Medicine ER -