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Lonicera quinquelocularis: A rich source of antioxidant for protection against chronic diseases.
Pak J Pharm Sci. 2017 Mar; 30(2):347-353.PJ

Abstract

The purpose of the research work was to examine the in vitro antioxidant activity of the different aqueous and organic fractions of Lonicera quinquelocularis Hardwicke. The methanol extract was dissolved in distilled water and fractioned with n-hexane, chloroform, ethyl acetate and n-butanol, successively. The antioxidant potential of the remaining aqueous and organic fractions was determined by using 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) scavenging activity, total antioxidant activity, ferric reducing antioxidant power (FRAP) assay, ferric thiocyanate assay and total phenolics method. Among these fractions ethyl acetate fraction displayed the maximum antioxidant activity with IC50 of (11.13±0.12µg/ml). It also exhibited the highest total antioxidant activity (0.595±0.00), FRAP value (128.2±4.54µg/mL) and total phenolic contents (66.89±7.73µg/g) as compared to other organic fractions. Phytochemical investigation of the above mentioned fractions showed the presence of flavanoids, phenolics, terpenoids, sugars, alkaloids, tannins, saponins and cardiac glycosides in appreciable amounts, which have major contribution towards antioxidant activity.

Authors+Show Affiliations

Department of Chemistry, Government College University, Lahore, Pakistan.Department of Chemistry, Government College University, Lahore, Pakistan.Department of Chemistry, Government College University, Lahore, Pakistan.Department of Chemistry, Government College University, Lahore, Pakistan.Department of Botany, Mirpur University of Science & Technology (MUST), Bhimber Campus, AJK.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

28649055

Citation

Siddiqui, Sabahat Zahra, et al. "Lonicera Quinquelocularis: a Rich Source of Antioxidant for Protection Against Chronic Diseases." Pakistan Journal of Pharmaceutical Sciences, vol. 30, no. 2, 2017, pp. 347-353.
Siddiqui SZ, Saleem H, Abbasi MA, et al. Lonicera quinquelocularis: A rich source of antioxidant for protection against chronic diseases. Pak J Pharm Sci. 2017;30(2):347-353.
Siddiqui, S. Z., Saleem, H., Abbasi, M. A., Rehman, A., & Ajaib, M. (2017). Lonicera quinquelocularis: A rich source of antioxidant for protection against chronic diseases. Pakistan Journal of Pharmaceutical Sciences, 30(2), 347-353.
Siddiqui SZ, et al. Lonicera Quinquelocularis: a Rich Source of Antioxidant for Protection Against Chronic Diseases. Pak J Pharm Sci. 2017;30(2):347-353. PubMed PMID: 28649055.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Lonicera quinquelocularis: A rich source of antioxidant for protection against chronic diseases. AU - Siddiqui,Sabahat Zahra, AU - Saleem,Hina, AU - Abbasi,Muhammad Athar, AU - Rehman,Azizur, AU - Ajaib,Muhammad, PY - 2017/6/27/entrez PY - 2017/6/27/pubmed PY - 2019/7/2/medline SP - 347 EP - 353 JF - Pakistan journal of pharmaceutical sciences JO - Pak J Pharm Sci VL - 30 IS - 2 N2 - The purpose of the research work was to examine the in vitro antioxidant activity of the different aqueous and organic fractions of Lonicera quinquelocularis Hardwicke. The methanol extract was dissolved in distilled water and fractioned with n-hexane, chloroform, ethyl acetate and n-butanol, successively. The antioxidant potential of the remaining aqueous and organic fractions was determined by using 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) scavenging activity, total antioxidant activity, ferric reducing antioxidant power (FRAP) assay, ferric thiocyanate assay and total phenolics method. Among these fractions ethyl acetate fraction displayed the maximum antioxidant activity with IC50 of (11.13±0.12µg/ml). It also exhibited the highest total antioxidant activity (0.595±0.00), FRAP value (128.2±4.54µg/mL) and total phenolic contents (66.89±7.73µg/g) as compared to other organic fractions. Phytochemical investigation of the above mentioned fractions showed the presence of flavanoids, phenolics, terpenoids, sugars, alkaloids, tannins, saponins and cardiac glycosides in appreciable amounts, which have major contribution towards antioxidant activity. SN - 1011-601X UR - https://www.unboundmedicine.com/medline/citation/28649055/Lonicera_quinquelocularis:_A_rich_source_of_antioxidant_for_protection_against_chronic_diseases_ L2 - https://medlineplus.gov/antioxidants.html DB - PRIME DP - Unbound Medicine ER -
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