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Acute periprosthetic knee infection: is there still a role for DAIR?
Acta Biomed 2017; 88(2S):84-91AB

Abstract

BACKGROUND AND AIM OF THE WORK

Periprosthetic knee infection is a rare complication associated with prosthetic failure; incidence change from 0,4-2% of primary total knee replacement and 5.6% in revisions. Indications for debridment, antibiotics and implant retention (DAIR) are early acute infections or acute delayed infection. Aim of the work is to check if this technique is still a successful in early infections.

METHODS

We have analyzed recent literature data on DAIR and all DAIR procedures in our clinic in the last 10 years, the mean time between onset of symptoms and surgery, the mean antibiotic therapy duration and results we have obtained. We evaluate the diagnostic process and different treatments in early knee periprosthetic infections, especially the DAIR approach.

RESULTS

If correct indications are followed, DAIR has a success rate in 31-100% of the cases; if it is applied in late chronic infection the success rate is 28-62%. In our experience DAIR has an 80% success rate: in 20 patients treated with DAIR we had 4 failures.

CONCLUSIONS

DAIR can be considered a successful treatment, but it depends from individual patient factors, from the microorganisms involved, from the duration of antibiotic therapy and from correct choice in timing and in execution of DAIR by the orthopedic surgeon.

Authors+Show Affiliations

. paolo.dibenedetto@asuiud.sanita.fvg.it.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

28657569

Citation

Di Benedetto, Paolo, et al. "Acute Periprosthetic Knee Infection: Is There Still a Role for DAIR?" Acta Bio-medica : Atenei Parmensis, vol. 88, no. 2S, 2017, pp. 84-91.
Di Benedetto P, Di Benedetto ED, Salviato D, et al. Acute periprosthetic knee infection: is there still a role for DAIR? Acta Biomed. 2017;88(2S):84-91.
Di Benedetto, P., Di Benedetto, E. D., Salviato, D., Beltrame, A., Gissoni, R., Cainero, V., & Causero, A. (2017). Acute periprosthetic knee infection: is there still a role for DAIR? Acta Bio-medica : Atenei Parmensis, 88(2S), pp. 84-91. doi:10.23750/abm.v88i2 -S.6518.
Di Benedetto P, et al. Acute Periprosthetic Knee Infection: Is There Still a Role for DAIR. Acta Biomed. 2017 06 7;88(2S):84-91. PubMed PMID: 28657569.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Acute periprosthetic knee infection: is there still a role for DAIR? AU - Di Benedetto,Paolo, AU - Di Benedetto,Enrico Daniele, AU - Salviato,Daniele, AU - Beltrame,Alessandro, AU - Gissoni,Renato, AU - Cainero,Vanni, AU - Causero,Araldo, Y1 - 2017/06/07/ PY - 2017/06/01/received PY - 2017/6/29/entrez PY - 2017/6/29/pubmed PY - 2018/5/1/medline KW - knee, periprostethic, acute, infection, debridement SP - 84 EP - 91 JF - Acta bio-medica : Atenei Parmensis JO - Acta Biomed VL - 88 IS - 2S N2 - BACKGROUND AND AIM OF THE WORK: Periprosthetic knee infection is a rare complication associated with prosthetic failure; incidence change from 0,4-2% of primary total knee replacement and 5.6% in revisions. Indications for debridment, antibiotics and implant retention (DAIR) are early acute infections or acute delayed infection. Aim of the work is to check if this technique is still a successful in early infections. METHODS: We have analyzed recent literature data on DAIR and all DAIR procedures in our clinic in the last 10 years, the mean time between onset of symptoms and surgery, the mean antibiotic therapy duration and results we have obtained. We evaluate the diagnostic process and different treatments in early knee periprosthetic infections, especially the DAIR approach. RESULTS: If correct indications are followed, DAIR has a success rate in 31-100% of the cases; if it is applied in late chronic infection the success rate is 28-62%. In our experience DAIR has an 80% success rate: in 20 patients treated with DAIR we had 4 failures. CONCLUSIONS: DAIR can be considered a successful treatment, but it depends from individual patient factors, from the microorganisms involved, from the duration of antibiotic therapy and from correct choice in timing and in execution of DAIR by the orthopedic surgeon. SN - 2531-6745 UR - https://www.unboundmedicine.com/medline/citation/28657569/Acute_periprosthetic_knee_infection:_is_there_still_a_role_for_DAIR L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/28657569/ DB - PRIME DP - Unbound Medicine ER -