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[Interaction of the endo- and exocrine pancreas].
Schweiz Med Wochenschr. 1985 Sep 21; 115(38):1299-306.SM

Abstract

The pancreas has both exocrine and endocrine components. The exocrine component of the pancreas manufactures, stores, and packages digestive enzymes for digestion of food, whereas the endocrine secretes hormones that regulate the metabolism and utilization of the absorbed nutrient components. Both components are closely related, not only anatomically but also functionally. The available evidence to support the concept of a close interrelationship of endocrine and exocrine pancreatic function is summarized. It is shown that the endocrine part exerts a profound effect upon the digestive activities of the organ, and that impairment of endocrine function, such as diabetes, severely affects the exocrine component of the gland. Furthermore, dysfunction of the exocrine gland, as in chronic pancreatitis, progressively disturbs the function of the islet cell hormones. The interactions are governed by a complicated control system, the details of which are not yet clarified. As in any partnership, dysfunction of one partner severely affects the other and vice versa.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't
Review

Language

ger

PubMed ID

2865807

Citation

Gyr, K, et al. "[Interaction of the Endo- and Exocrine Pancreas]." Schweizerische Medizinische Wochenschrift, vol. 115, no. 38, 1985, pp. 1299-306.
Gyr K, Beglinger C, Stalder GA. [Interaction of the endo- and exocrine pancreas]. Schweiz Med Wochenschr. 1985;115(38):1299-306.
Gyr, K., Beglinger, C., & Stalder, G. A. (1985). [Interaction of the endo- and exocrine pancreas]. Schweizerische Medizinische Wochenschrift, 115(38), 1299-306.
Gyr K, Beglinger C, Stalder GA. [Interaction of the Endo- and Exocrine Pancreas]. Schweiz Med Wochenschr. 1985 Sep 21;115(38):1299-306. PubMed PMID: 2865807.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Interaction of the endo- and exocrine pancreas]. AU - Gyr,K, AU - Beglinger,C, AU - Stalder,G A, PY - 1985/9/21/pubmed PY - 1985/9/21/medline PY - 1985/9/21/entrez SP - 1299 EP - 306 JF - Schweizerische medizinische Wochenschrift JO - Schweiz Med Wochenschr VL - 115 IS - 38 N2 - The pancreas has both exocrine and endocrine components. The exocrine component of the pancreas manufactures, stores, and packages digestive enzymes for digestion of food, whereas the endocrine secretes hormones that regulate the metabolism and utilization of the absorbed nutrient components. Both components are closely related, not only anatomically but also functionally. The available evidence to support the concept of a close interrelationship of endocrine and exocrine pancreatic function is summarized. It is shown that the endocrine part exerts a profound effect upon the digestive activities of the organ, and that impairment of endocrine function, such as diabetes, severely affects the exocrine component of the gland. Furthermore, dysfunction of the exocrine gland, as in chronic pancreatitis, progressively disturbs the function of the islet cell hormones. The interactions are governed by a complicated control system, the details of which are not yet clarified. As in any partnership, dysfunction of one partner severely affects the other and vice versa. SN - 0036-7672 UR - https://www.unboundmedicine.com/medline/citation/2865807/[Interaction_of_the_endo__and_exocrine_pancreas]_ DB - PRIME DP - Unbound Medicine ER -