Tags

Type your tag names separated by a space and hit enter

Cost-effectiveness analysis of N95 respirators and medical masks to protect healthcare workers in China from respiratory infections.
BMC Infect Dis. 2017 07 03; 17(1):464.BI

Abstract

BACKGROUND

There are substantial differences between the costs of medical masks and N95 respirators. Cost-effectiveness analysis is required to assist decision-makers evaluating alternative healthcare worker (HCW) mask/respirator strategies. This study aims to compare the cost-effectiveness of N95 respirators and medical masks for protecting HCWs in Beijing, China.

METHODS

We developed a cost-effectiveness analysis model utilising efficacy and resource use data from two cluster randomised clinical trials assessing various mask/respirator strategies conducted in HCWs in Level 2 and 3 Beijing hospitals for the 2008-09 and 2009-10 influenza seasons. The main outcome measure was the incremental cost-effectiveness ratio (ICER) per clinical respiratory illness (CRI) case prevented. We used a societal perspective which included intervention costs, the healthcare costs of CRI in HCWs and absenteeism costs.

RESULTS

The incremental cost to prevent a CRI case with continuous use of N95 respirators when compared to medical masks ranged from US $490-$1230 (approx. 3000-7600 RMB). One-way sensitivity analysis indicated that the CRI attack rate and intervention effectiveness had the greatest impact on cost-effectiveness.

CONCLUSIONS

The determination of cost-effectiveness for mask/respirator strategies will depend on the willingness to pay to prevent a CRI case in a HCW, which will vary between countries. In the case of a highly pathogenic pandemic, respirator use in HCWs would likely be a cost-effective intervention.

Authors+Show Affiliations

School of Public Health and Community Medicine, The University of New South Wales, Sydney, NSW, 2052, Australia. s.mukerji@unsw.edu.au.School of Public Health and Community Medicine, The University of New South Wales, Sydney, NSW, 2052, Australia. National Centre for Immunisation Research and Surveillance of Vaccine Preventable Diseases (NCIRS), University of Sydney, Westmead, NSW, Australia.School of Public Health and Community Medicine, The University of New South Wales, Sydney, NSW, 2052, Australia.The Beijing Centre for Disease Control and Prevention, Beijing, China.The Beijing Centre for Disease Control and Prevention, Beijing, China.The Beijing Centre for Disease Control and Prevention, Beijing, China.School of Public Health and Community Medicine, The University of New South Wales, Sydney, NSW, 2052, Australia.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

28673259

Citation

Mukerji, Shohini, et al. "Cost-effectiveness Analysis of N95 Respirators and Medical Masks to Protect Healthcare Workers in China From Respiratory Infections." BMC Infectious Diseases, vol. 17, no. 1, 2017, p. 464.
Mukerji S, MacIntyre CR, Seale H, et al. Cost-effectiveness analysis of N95 respirators and medical masks to protect healthcare workers in China from respiratory infections. BMC Infect Dis. 2017;17(1):464.
Mukerji, S., MacIntyre, C. R., Seale, H., Wang, Q., Yang, P., Wang, X., & Newall, A. T. (2017). Cost-effectiveness analysis of N95 respirators and medical masks to protect healthcare workers in China from respiratory infections. BMC Infectious Diseases, 17(1), 464. https://doi.org/10.1186/s12879-017-2564-9
Mukerji S, et al. Cost-effectiveness Analysis of N95 Respirators and Medical Masks to Protect Healthcare Workers in China From Respiratory Infections. BMC Infect Dis. 2017 07 3;17(1):464. PubMed PMID: 28673259.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cost-effectiveness analysis of N95 respirators and medical masks to protect healthcare workers in China from respiratory infections. AU - Mukerji,Shohini, AU - MacIntyre,C Raina, AU - Seale,Holly, AU - Wang,Quanyi, AU - Yang,Peng, AU - Wang,Xiaoli, AU - Newall,Anthony T, Y1 - 2017/07/03/ PY - 2016/09/10/received PY - 2017/06/23/accepted PY - 2017/7/5/entrez PY - 2017/7/5/pubmed PY - 2017/10/3/medline KW - Cost-effectiveness KW - Economic evaluation KW - Healthcare worker KW - Mask KW - N95 respirator SP - 464 EP - 464 JF - BMC infectious diseases JO - BMC Infect Dis VL - 17 IS - 1 N2 - BACKGROUND: There are substantial differences between the costs of medical masks and N95 respirators. Cost-effectiveness analysis is required to assist decision-makers evaluating alternative healthcare worker (HCW) mask/respirator strategies. This study aims to compare the cost-effectiveness of N95 respirators and medical masks for protecting HCWs in Beijing, China. METHODS: We developed a cost-effectiveness analysis model utilising efficacy and resource use data from two cluster randomised clinical trials assessing various mask/respirator strategies conducted in HCWs in Level 2 and 3 Beijing hospitals for the 2008-09 and 2009-10 influenza seasons. The main outcome measure was the incremental cost-effectiveness ratio (ICER) per clinical respiratory illness (CRI) case prevented. We used a societal perspective which included intervention costs, the healthcare costs of CRI in HCWs and absenteeism costs. RESULTS: The incremental cost to prevent a CRI case with continuous use of N95 respirators when compared to medical masks ranged from US $490-$1230 (approx. 3000-7600 RMB). One-way sensitivity analysis indicated that the CRI attack rate and intervention effectiveness had the greatest impact on cost-effectiveness. CONCLUSIONS: The determination of cost-effectiveness for mask/respirator strategies will depend on the willingness to pay to prevent a CRI case in a HCW, which will vary between countries. In the case of a highly pathogenic pandemic, respirator use in HCWs would likely be a cost-effective intervention. SN - 1471-2334 UR - https://www.unboundmedicine.com/medline/citation/28673259/Cost_effectiveness_analysis_of_N95_respirators_and_medical_masks_to_protect_healthcare_workers_in_China_from_respiratory_infections_ L2 - https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-017-2564-9 DB - PRIME DP - Unbound Medicine ER -