Tags

Type your tag names separated by a space and hit enter

HEV and transfusion-recipient risk.
Transfus Clin Biol. 2017 Sep; 24(3):176-181.TC

Abstract

HEV infections are mainly food- and water-borne but transfusion-transmission has occurred in both developing and developed countries. The infection is usually asymptomatic but it can lead to fulminant hepatitis in patients with underlying liver disease and pregnant women living in developing countries. It also causes chronic hepatitis E, with progressive fibrosis and cirrhosis, in approximately 60% of immunocompromised patients infected with HEV genotype 3. The risk of a transfusion-transmitted HEV infection is linked to the frequency of viremia in blood donors, the donor virus load and the volume of plasma in the final transfused blood component. Several developed countries have adopted measures to improve blood safety based on the epidemiology of HEV.

Authors+Show Affiliations

Department of virology, National reference center for hepatitis E virus, CHU Purpan, IFB, 330, avenue de Grande-Bretagne, TSA 40031, 31059 Toulouse, France; Inserm UMR 1043/CNRS UMR 5282, CPTP, center for pathophysiology of toulouse-Purpan, Toulouse university Paul-Sabatier, 31024 Toulouse, France. Electronic address: izopet.j@chu-toulouse.fr.Department of virology, National reference center for hepatitis E virus, CHU Purpan, IFB, 330, avenue de Grande-Bretagne, TSA 40031, 31059 Toulouse, France; Inserm UMR 1043/CNRS UMR 5282, CPTP, center for pathophysiology of toulouse-Purpan, Toulouse university Paul-Sabatier, 31024 Toulouse, France.Department of virology, National reference center for hepatitis E virus, CHU Purpan, IFB, 330, avenue de Grande-Bretagne, TSA 40031, 31059 Toulouse, France; Inserm UMR 1043/CNRS UMR 5282, CPTP, center for pathophysiology of toulouse-Purpan, Toulouse university Paul-Sabatier, 31024 Toulouse, France.Department of virology, National reference center for hepatitis E virus, CHU Purpan, IFB, 330, avenue de Grande-Bretagne, TSA 40031, 31059 Toulouse, France.Inserm UMR 1043/CNRS UMR 5282, CPTP, center for pathophysiology of toulouse-Purpan, Toulouse university Paul-Sabatier, 31024 Toulouse, France; Department of nephrology and organ transplantation, CHU Rangueil, 31059 Toulouse, France.Department of virology, National reference center for hepatitis E virus, CHU Purpan, IFB, 330, avenue de Grande-Bretagne, TSA 40031, 31059 Toulouse, France; Inserm UMR 1043/CNRS UMR 5282, CPTP, center for pathophysiology of toulouse-Purpan, Toulouse university Paul-Sabatier, 31024 Toulouse, France.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

28690036

Citation

Izopet, J, et al. "HEV and Transfusion-recipient Risk." Transfusion Clinique Et Biologique : Journal De La Societe Francaise De Transfusion Sanguine, vol. 24, no. 3, 2017, pp. 176-181.
Izopet J, Lhomme S, Chapuy-Regaud S, et al. HEV and transfusion-recipient risk. Transfus Clin Biol. 2017;24(3):176-181.
Izopet, J., Lhomme, S., Chapuy-Regaud, S., Mansuy, J. M., Kamar, N., & Abravanel, F. (2017). HEV and transfusion-recipient risk. Transfusion Clinique Et Biologique : Journal De La Societe Francaise De Transfusion Sanguine, 24(3), 176-181. https://doi.org/10.1016/j.tracli.2017.06.012
Izopet J, et al. HEV and Transfusion-recipient Risk. Transfus Clin Biol. 2017;24(3):176-181. PubMed PMID: 28690036.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - HEV and transfusion-recipient risk. AU - Izopet,J, AU - Lhomme,S, AU - Chapuy-Regaud,S, AU - Mansuy,J-M, AU - Kamar,N, AU - Abravanel,F, Y1 - 2017/07/06/ PY - 2017/06/08/received PY - 2017/06/08/accepted PY - 2017/7/12/pubmed PY - 2018/7/20/medline PY - 2017/7/11/entrez KW - Blood donors KW - Blood safety KW - Donneurs de sang KW - Genotype 3 KW - Génotype 3 KW - HEV KW - Sécurité transfusionnelle KW - Transfusion KW - VHE SP - 176 EP - 181 JF - Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine JO - Transfus Clin Biol VL - 24 IS - 3 N2 - HEV infections are mainly food- and water-borne but transfusion-transmission has occurred in both developing and developed countries. The infection is usually asymptomatic but it can lead to fulminant hepatitis in patients with underlying liver disease and pregnant women living in developing countries. It also causes chronic hepatitis E, with progressive fibrosis and cirrhosis, in approximately 60% of immunocompromised patients infected with HEV genotype 3. The risk of a transfusion-transmitted HEV infection is linked to the frequency of viremia in blood donors, the donor virus load and the volume of plasma in the final transfused blood component. Several developed countries have adopted measures to improve blood safety based on the epidemiology of HEV. SN - 1953-8022 UR - https://www.unboundmedicine.com/medline/citation/28690036/HEV_and_transfusion_recipient_risk_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1246-7820(17)30093-9 DB - PRIME DP - Unbound Medicine ER -