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[Unusual abdominal apudomas. I. Cushing syndrome in association with Zollinger-Ellison syndrome in an endocrine pancreas tumor].
Zentralbl Allg Pathol. 1985; 130(5):369-74.ZA

Abstract

Ectopic production of ACTH is observed in 6% of patients with Cushing syndrome. Ten percent of these cases are related to endocrine pancreatic tumors. In a few cases a multiplicity of hormones are produced. The combination with a Zollinger-Ellison syndrome is very infrequent. In the present case, a female patient aged 54, there was an interval between the onset of Zollinger-Ellison and Cushing syndrome. The combination of bilaterally enlarged adrenals in the absence of an adrenal adenoma and the presence of Crooke-cells in the adenohypophysis in a patient with Cushing syndrome are of diagnostic significance. This trias should always alert the physician to the possibility of extrahypophyseal ACTH production.

Authors

Gottschalk J
No affiliation info available
Buntrock P
No affiliation info available
Gerl H
No affiliation info available
Knappe G
No affiliation info available
Rohde W
No affiliation info available

MeSH

Adrenocorticotropic HormoneApudomaAutopsyCushing SyndromeFemaleHumansLiver NeoplasmsMiddle AgedMultiple Endocrine NeoplasiaPancreatic NeoplasmsZollinger-Ellison Syndrome

Pub Type(s)

Case Reports
Journal Article

Language

ger

PubMed ID

2869627

Citation

Gottschalk, J, et al. "[Unusual Abdominal Apudomas. I. Cushing Syndrome in Association With Zollinger-Ellison Syndrome in an Endocrine Pancreas Tumor]." Zentralblatt Fur Allgemeine Pathologie U. Pathologische Anatomie, vol. 130, no. 5, 1985, pp. 369-74.
Gottschalk J, Buntrock P, Gerl H, et al. [Unusual abdominal apudomas. I. Cushing syndrome in association with Zollinger-Ellison syndrome in an endocrine pancreas tumor]. Zentralbl Allg Pathol. 1985;130(5):369-74.
Gottschalk, J., Buntrock, P., Gerl, H., Knappe, G., & Rohde, W. (1985). [Unusual abdominal apudomas. I. Cushing syndrome in association with Zollinger-Ellison syndrome in an endocrine pancreas tumor]. Zentralblatt Fur Allgemeine Pathologie U. Pathologische Anatomie, 130(5), 369-74.
Gottschalk J, et al. [Unusual Abdominal Apudomas. I. Cushing Syndrome in Association With Zollinger-Ellison Syndrome in an Endocrine Pancreas Tumor]. Zentralbl Allg Pathol. 1985;130(5):369-74. PubMed PMID: 2869627.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Unusual abdominal apudomas. I. Cushing syndrome in association with Zollinger-Ellison syndrome in an endocrine pancreas tumor]. AU - Gottschalk,J, AU - Buntrock,P, AU - Gerl,H, AU - Knappe,G, AU - Rohde,W, PY - 1985/1/1/pubmed PY - 1985/1/1/medline PY - 1985/1/1/entrez SP - 369 EP - 74 JF - Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie JO - Zentralbl Allg Pathol VL - 130 IS - 5 N2 - Ectopic production of ACTH is observed in 6% of patients with Cushing syndrome. Ten percent of these cases are related to endocrine pancreatic tumors. In a few cases a multiplicity of hormones are produced. The combination with a Zollinger-Ellison syndrome is very infrequent. In the present case, a female patient aged 54, there was an interval between the onset of Zollinger-Ellison and Cushing syndrome. The combination of bilaterally enlarged adrenals in the absence of an adrenal adenoma and the presence of Crooke-cells in the adenohypophysis in a patient with Cushing syndrome are of diagnostic significance. This trias should always alert the physician to the possibility of extrahypophyseal ACTH production. SN - 0044-4030 UR - https://www.unboundmedicine.com/medline/citation/2869627/[Unusual_abdominal_apudomas__I__Cushing_syndrome_in_association_with_Zollinger_Ellison_syndrome_in_an_endocrine_pancreas_tumor]_ DB - PRIME DP - Unbound Medicine ER -