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Deodorizing Substance in Black Cumin (Nigella sativa L.) Seed Oil.
J Oleo Sci. 2017 Aug 01; 66(8):877-882.JO

Abstract

A deodorizing substance in black cumin (Nigella sativa L.), a spice for curry and vegetable foods in Southwest Asia, was examined. The essential oil prepared from the seeds of this plant exhibited strong deodorizing activity against methyl mercaptan, which is a main factor in oral malodor. After purification with silica gel column chromatography, the active substance in black cumin seed oil was identified as thymoquinone. This monoterpenic quinone functions as the main deodorizing substance in this oil against methyl mercaptan. Metabolite analysis suggested that the deodorizing activity may be generated by the addition of a reactive quinone molecule to methyl mercaptan. In the present study, the menthane-type quinone and phenol derivatives exhibited deodorizing activities via this mechanism.

Authors+Show Affiliations

Applied Science Department, Inabata Koryo Co., Ltd.Applied Science Department, Inabata Koryo Co., Ltd.Laboratory for Oral Health Science, Inabata Koryo Co., Ltd.Department of Applied Biological Chemistry, School of Agriculture, Kindai University.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

28701649

Citation

Nakasugi, Toru, et al. "Deodorizing Substance in Black Cumin (Nigella Sativa L.) Seed Oil." Journal of Oleo Science, vol. 66, no. 8, 2017, pp. 877-882.
Nakasugi T, Murakawa T, Shibuya K, et al. Deodorizing Substance in Black Cumin (Nigella sativa L.) Seed Oil. J Oleo Sci. 2017;66(8):877-882.
Nakasugi, T., Murakawa, T., Shibuya, K., & Morimoto, M. (2017). Deodorizing Substance in Black Cumin (Nigella sativa L.) Seed Oil. Journal of Oleo Science, 66(8), 877-882. https://doi.org/10.5650/jos.ess17001
Nakasugi T, et al. Deodorizing Substance in Black Cumin (Nigella Sativa L.) Seed Oil. J Oleo Sci. 2017 Aug 1;66(8):877-882. PubMed PMID: 28701649.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Deodorizing Substance in Black Cumin (Nigella sativa L.) Seed Oil. AU - Nakasugi,Toru, AU - Murakawa,Takushi, AU - Shibuya,Koji, AU - Morimoto,Masanori, Y1 - 2017/07/12/ PY - 2017/7/14/pubmed PY - 2017/10/11/medline PY - 2017/7/14/entrez KW - black cumin KW - oral deodorant KW - thymoquinone SP - 877 EP - 882 JF - Journal of oleo science JO - J Oleo Sci VL - 66 IS - 8 N2 - A deodorizing substance in black cumin (Nigella sativa L.), a spice for curry and vegetable foods in Southwest Asia, was examined. The essential oil prepared from the seeds of this plant exhibited strong deodorizing activity against methyl mercaptan, which is a main factor in oral malodor. After purification with silica gel column chromatography, the active substance in black cumin seed oil was identified as thymoquinone. This monoterpenic quinone functions as the main deodorizing substance in this oil against methyl mercaptan. Metabolite analysis suggested that the deodorizing activity may be generated by the addition of a reactive quinone molecule to methyl mercaptan. In the present study, the menthane-type quinone and phenol derivatives exhibited deodorizing activities via this mechanism. SN - 1347-3352 UR - https://www.unboundmedicine.com/medline/citation/28701649/Deodorizing_Substance_in_Black_Cumin__Nigella_sativa_L___Seed_Oil_ L2 - https://dx.doi.org/10.5650/jos.ess17001 DB - PRIME DP - Unbound Medicine ER -