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Cronkhite-Canada Syndrome: A Rare Cause of Chronic Diarrhea.
Gastroenterology Res. 2017 Jun; 10(3):196-198.GR

Abstract

Cronkhite-Canada syndrome (CCS) is a rare non-hereditary disease characterized by chronic diarrhea, diffuse intestinal polyposis and onychodystrophy. We present here a case of a middle-aged female who presented with chronic intermittent bloody diarrhea associated alopecia and loss of finger and toe nails. Labs were remarkable for microcytic anemia and severe hypoalbuminemia. Endoscopy showed numerous polyps scattered throughout the colon. She was treated with nutritional support and corticosteroid with complete resolution of her symptoms and endoscopic findings. CCS is associated with high mortality and gastrointestinal malignancies. Clinicians should consider CCS in a patient with unexplained chronic diarrhea and ectodermal abnormalities.

Authors+Show Affiliations

Bassett Medical Center, Cooperstown, NY, USA.Bassett Medical Center, Cooperstown, NY, USA.Dow University of Health and Sciences, Karachi, Pakistan.Dow University of Health and Sciences, Karachi, Pakistan.Bassett Medical Center, Cooperstown, NY, USA.

Pub Type(s)

Case Reports

Language

eng

PubMed ID

28725309

Citation

Iqbal, Umair, et al. "Cronkhite-Canada Syndrome: a Rare Cause of Chronic Diarrhea." Gastroenterology Research, vol. 10, no. 3, 2017, pp. 196-198.
Iqbal U, Chaudhary A, Karim MA, et al. Cronkhite-Canada Syndrome: A Rare Cause of Chronic Diarrhea. Gastroenterology Res. 2017;10(3):196-198.
Iqbal, U., Chaudhary, A., Karim, M. A., Anwar, H., & Merrell, N. (2017). Cronkhite-Canada Syndrome: A Rare Cause of Chronic Diarrhea. Gastroenterology Research, 10(3), 196-198. https://doi.org/10.14740/gr820w
Iqbal U, et al. Cronkhite-Canada Syndrome: a Rare Cause of Chronic Diarrhea. Gastroenterology Res. 2017;10(3):196-198. PubMed PMID: 28725309.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cronkhite-Canada Syndrome: A Rare Cause of Chronic Diarrhea. AU - Iqbal,Umair, AU - Chaudhary,Ahmad, AU - Karim,Muhammad Arsalan, AU - Anwar,Hafsa, AU - Merrell,Nancy, Y1 - 2017/06/30/ PY - 2017/03/06/received PY - 2017/04/03/accepted PY - 2017/7/21/entrez PY - 2017/7/21/pubmed PY - 2017/7/21/medline KW - Chronic diarrhea KW - Cronkhite-Canada syndrome KW - Intestinal polyposis KW - Onychodystrophy SP - 196 EP - 198 JF - Gastroenterology research JO - Gastroenterology Res VL - 10 IS - 3 N2 - Cronkhite-Canada syndrome (CCS) is a rare non-hereditary disease characterized by chronic diarrhea, diffuse intestinal polyposis and onychodystrophy. We present here a case of a middle-aged female who presented with chronic intermittent bloody diarrhea associated alopecia and loss of finger and toe nails. Labs were remarkable for microcytic anemia and severe hypoalbuminemia. Endoscopy showed numerous polyps scattered throughout the colon. She was treated with nutritional support and corticosteroid with complete resolution of her symptoms and endoscopic findings. CCS is associated with high mortality and gastrointestinal malignancies. Clinicians should consider CCS in a patient with unexplained chronic diarrhea and ectodermal abnormalities. SN - 1918-2805 UR - https://www.unboundmedicine.com/medline/citation/28725309/Cronkhite-Canada_Syndrome:_A_Rare_Cause_of_Chronic_Diarrhea L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/28725309/ DB - PRIME DP - Unbound Medicine ER -
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