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Genetic diversity of 21 autosomal STR loci in the Han population from Sichuan province, Southwest China.
Forensic Sci Int Genet. 2017 11; 31:e33-e35.FS

Abstract

Exploration of the ethnic origin and genetic differentiation of 56 Chinese officially recognized nationalities populations played a fundamental role in the research field of population genetics, forensic science, linguistics, anthropology, and archaeology. In the present study, population data of 21 autosomal STR loci (CSF1PO, D10S1248, D12S391, D13S317, D16S539, D18S51, D19S433, D21S11, D2S1338, D2S441, D3S1358, D5S818, D6S1043, D7S820, D8S1179, FGA, Penta D, Penta E, TH01, TPOX, and vWA) included in the AGCU EX22 kit in 2793 Southwest Han Chinese individuals was obtained and population genetic relationships among 28 Chinese populations were investigated. Our study indicated that the twenty-one autosomal STRs are highly polymorphic in the Sichuan Han population and can be used as a powerful tool in the routine forensic usage. MDS and phylogenetic analysis suggested that the Sichuan Han population kept a close genetic relationship with the southwest populations.

Authors+Show Affiliations

Department of Forensic Genetics, West China School of Preclinical Forensic Medicine, Sichuan University, Chengdu 610041, Sichuan, China.Department of Forensic Genetics, West China School of Preclinical Forensic Medicine, Sichuan University, Chengdu 610041, Sichuan, China.Department of Forensic Genetics, West China School of Preclinical Forensic Medicine, Sichuan University, Chengdu 610041, Sichuan, China.Department of Forensic Genetics, West China School of Preclinical Forensic Medicine, Sichuan University, Chengdu 610041, Sichuan, China.Department of Forensic Genetics, West China School of Preclinical Forensic Medicine, Sichuan University, Chengdu 610041, Sichuan, China.Department of Forensic Genetics, West China School of Preclinical Forensic Medicine, Sichuan University, Chengdu 610041, Sichuan, China.Department of Forensic Genetics, West China School of Preclinical Forensic Medicine, Sichuan University, Chengdu 610041, Sichuan, China.Department of Forensic Genetics, West China School of Preclinical Forensic Medicine, Sichuan University, Chengdu 610041, Sichuan, China.Department of Forensic Genetics, West China School of Preclinical Forensic Medicine, Sichuan University, Chengdu 610041, Sichuan, China.Department of Forensic Genetics, West China School of Preclinical Forensic Medicine, Sichuan University, Chengdu 610041, Sichuan, China.Department of Forensic Genetics, West China School of Preclinical Forensic Medicine, Sichuan University, Chengdu 610041, Sichuan, China. Electronic address: wujin2028@163.com.

Pub Type(s)

Letter
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

28743451

Citation

He, Guanglin, et al. "Genetic Diversity of 21 Autosomal STR Loci in the Han Population From Sichuan Province, Southwest China." Forensic Science International. Genetics, vol. 31, 2017, pp. e33-e35.
He G, Li Y, Wang Z, et al. Genetic diversity of 21 autosomal STR loci in the Han population from Sichuan province, Southwest China. Forensic Sci Int Genet. 2017;31:e33-e35.
He, G., Li, Y., Wang, Z., Liang, W., Luo, H., Liao, M., Zhang, J., Yan, J., Li, Y., Hou, Y., & Wu, J. (2017). Genetic diversity of 21 autosomal STR loci in the Han population from Sichuan province, Southwest China. Forensic Science International. Genetics, 31, e33-e35. https://doi.org/10.1016/j.fsigen.2017.07.006
He G, et al. Genetic Diversity of 21 Autosomal STR Loci in the Han Population From Sichuan Province, Southwest China. Forensic Sci Int Genet. 2017;31:e33-e35. PubMed PMID: 28743451.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Genetic diversity of 21 autosomal STR loci in the Han population from Sichuan province, Southwest China. AU - He,Guanglin, AU - Li,Ye, AU - Wang,Zheng, AU - Liang,Weibo, AU - Luo,Haibo, AU - Liao,Miao, AU - Zhang,Ji, AU - Yan,Jing, AU - Li,Yingbi, AU - Hou,Yiping, AU - Wu,Jin, Y1 - 2017/07/17/ PY - 2017/05/31/received PY - 2017/07/09/revised PY - 2017/07/12/accepted PY - 2017/7/27/pubmed PY - 2017/12/12/medline PY - 2017/7/27/entrez KW - AGCU EX22 KW - Genetic polymorphisms KW - Han nationality SP - e33 EP - e35 JF - Forensic science international. Genetics JO - Forensic Sci Int Genet VL - 31 N2 - Exploration of the ethnic origin and genetic differentiation of 56 Chinese officially recognized nationalities populations played a fundamental role in the research field of population genetics, forensic science, linguistics, anthropology, and archaeology. In the present study, population data of 21 autosomal STR loci (CSF1PO, D10S1248, D12S391, D13S317, D16S539, D18S51, D19S433, D21S11, D2S1338, D2S441, D3S1358, D5S818, D6S1043, D7S820, D8S1179, FGA, Penta D, Penta E, TH01, TPOX, and vWA) included in the AGCU EX22 kit in 2793 Southwest Han Chinese individuals was obtained and population genetic relationships among 28 Chinese populations were investigated. Our study indicated that the twenty-one autosomal STRs are highly polymorphic in the Sichuan Han population and can be used as a powerful tool in the routine forensic usage. MDS and phylogenetic analysis suggested that the Sichuan Han population kept a close genetic relationship with the southwest populations. SN - 1878-0326 UR - https://www.unboundmedicine.com/medline/citation/28743451/Genetic_diversity_of_21_autosomal_STR_loci_in_the_Han_population_from_Sichuan_province_Southwest_China_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1872-4973(17)30148-5 DB - PRIME DP - Unbound Medicine ER -