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[Role of Mediterranean diet on the prevention of Alzheimer disease].
Rev Med Chil. 2017 Apr; 145(4):501-507.RM

Abstract

Type 2 diabetes and obesity are possible risk factors for Alzheimer’s disease and these can be modified by physical activity and changes in dietary patterns, such as switching to a Mediterranean diet. This diet includes fruits, vegetables, olive oil, fish and moderate wine intake. These foods provide vitamins, polyphenols and unsaturated fatty acids. This diet should be able to reduce oxidative stress. The inflammatory response is also reduced by unsaturated fatty acids, resulting in a lower expression and a lower production of pro-inflammatory cytokines. The Cardiovascular protection is related to the actions of polyphenols and unsaturated fatty acids on the vascular endothelium. The Mediterranean diet also can improve cardiovascular risk factors such as dyslipidemia, hypertension and metabolic syndrome. These beneficial effects of the Mediterranean diet should have a role in Alzheimer’s disease prevention.

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Authors+Show Affiliations

Miranda A
Departamento de Ciencias Biológicas y Químicas, Facultad de Ciencia, Universidad San Sebastián, Concepción, Chile, arnoldo.miranda@uss.cl.
Gómez-Gaete C
Departamento de Farmacia, Facultad de Farmacia, Universidad de Concepción, Concepción, Chile.
Mennickent S
Departamento de Farmacia, Facultad de Farmacia, Universidad de Concepción, Concepción, Chile.

MeSH

Alzheimer DiseaseDiet, MediterraneanHumansOxidative StressRisk Factors

Pub Type(s)

Journal Article
Review

Language

spa

PubMed ID

28748997

Citation

Miranda, Arnoldo, et al. "[Role of Mediterranean Diet On the Prevention of Alzheimer Disease]." Revista Medica De Chile, vol. 145, no. 4, 2017, pp. 501-507.
Miranda A, Gómez-Gaete C, Mennickent S. [Role of Mediterranean diet on the prevention of Alzheimer disease]. Rev Med Chil. 2017;145(4):501-507.
Miranda, A., Gómez-Gaete, C., & Mennickent, S. (2017). [Role of Mediterranean diet on the prevention of Alzheimer disease]. Revista Medica De Chile, 145(4), 501-507. https://doi.org/10.4067/S0034-98872017000400010
Miranda A, Gómez-Gaete C, Mennickent S. [Role of Mediterranean Diet On the Prevention of Alzheimer Disease]. Rev Med Chil. 2017;145(4):501-507. PubMed PMID: 28748997.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Role of Mediterranean diet on the prevention of Alzheimer disease]. AU - Miranda,Arnoldo, AU - Gómez-Gaete,Carolina, AU - Mennickent,Sigrid, PY - 2016/01/09/received PY - 2016/09/01/accepted PY - 2017/7/28/entrez PY - 2017/7/28/pubmed PY - 2017/8/25/medline SP - 501 EP - 507 JF - Revista medica de Chile JO - Rev Med Chil VL - 145 IS - 4 N2 - Type 2 diabetes and obesity are possible risk factors for Alzheimer’s disease and these can be modified by physical activity and changes in dietary patterns, such as switching to a Mediterranean diet. This diet includes fruits, vegetables, olive oil, fish and moderate wine intake. These foods provide vitamins, polyphenols and unsaturated fatty acids. This diet should be able to reduce oxidative stress. The inflammatory response is also reduced by unsaturated fatty acids, resulting in a lower expression and a lower production of pro-inflammatory cytokines. The Cardiovascular protection is related to the actions of polyphenols and unsaturated fatty acids on the vascular endothelium. The Mediterranean diet also can improve cardiovascular risk factors such as dyslipidemia, hypertension and metabolic syndrome. These beneficial effects of the Mediterranean diet should have a role in Alzheimer’s disease prevention. SN - 0717-6163 UR - https://www.unboundmedicine.com/medline/citation/28748997/[Role_of_Mediterranean_diet_on_the_prevention_of_Alzheimer_disease]_ L2 - http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872017000400010&lng=en&nrm=iso&tlng=en DB - PRIME DP - Unbound Medicine ER -