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Review of Organism Density and Bacteriologic Conversion of Sputum among Tuberculosis Patients.

Abstract

OBJECTIVE

This study sought to describe the trend of sputum organism density and the rate of bacteriological conversion among smear positive TB patients assessing care at the Komfo Anokye Teaching Hospital (KATH), Kumasi, Ghana.

METHODS

We conducted a retrospective patient folder review from January 2013 to March 2016 at the KATH, a tertiary hospital in Ghana. The data was entered into Microsoft Access database and exported into STATA for analysis. We applied basic descriptive statistics to study variables. Sputum conversion rate (SCR) was estimated using the number of negative tests recorded over a period (numerator) and the number of patients reported in the same period (denominator) and expressed as a percentage.

RESULTS

A total of 278 patient records with sputum smear positive at onset were studied. Before treatment sputum density detected in smear microscopy was as follows: 1 acid-fast bacillus (+) (n = 114), scanty (n = 19), ++ (n = 67), and +++ (n = 78). We recorded sputum conversion rate of 80.90%, 94.56%, and 98.31% in the intensive, continuation, and completion phases, respectively.

CONCLUSION

This study has shown an increasing trend in sputum conversion of smear positive pulmonary tuberculosis and an increasing trend in loss to follow-ups among tuberculosis patients on treatment.

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  • Authors+Show Affiliations

    ,

    Public Health Unit, Komfo Anokye Teaching Hospital, Kumasi, Ghana. Research and Development Unit, Komfo Anokye Teaching Hospital, Kumasi, Ghana.

    ,

    Department of Child Health, Komfo Anokye Teaching Hospital, Kumasi, Ghana.

    ,

    Research and Development Unit, Komfo Anokye Teaching Hospital, Kumasi, Ghana. Department of Child Health, Komfo Anokye Teaching Hospital, Kumasi, Ghana.

    ,

    Public Health Unit, Komfo Anokye Teaching Hospital, Kumasi, Ghana.

    ,

    Public Health Unit, Komfo Anokye Teaching Hospital, Kumasi, Ghana.

    ,

    Research and Development Unit, Komfo Anokye Teaching Hospital, Kumasi, Ghana.

    ,

    Public Health Unit, Komfo Anokye Teaching Hospital, Kumasi, Ghana.

    ,

    Research and Development Unit, Komfo Anokye Teaching Hospital, Kumasi, Ghana.

    ,

    Research and Development Unit, Komfo Anokye Teaching Hospital, Kumasi, Ghana.

    Kumasi Centre for Collaborative Research in Tropical Medicine, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

    Source

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    28781995

    Citation

    Osei, Francis Adjei, et al. "Review of Organism Density and Bacteriologic Conversion of Sputum Among Tuberculosis Patients." International Scholarly Research Notices, vol. 2017, 2017, p. 7052583.
    Osei FA, Enimil A, Ansong D, et al. Review of Organism Density and Bacteriologic Conversion of Sputum among Tuberculosis Patients. Int Sch Res Notices. 2017;2017:7052583.
    Osei, F. A., Enimil, A., Ansong, D., Laryea, D. O., Mensah, N. K., Amuzu, E. X., ... Dekugmen Yar, D. (2017). Review of Organism Density and Bacteriologic Conversion of Sputum among Tuberculosis Patients. International Scholarly Research Notices, 2017, p. 7052583. doi:10.1155/2017/7052583.
    Osei FA, et al. Review of Organism Density and Bacteriologic Conversion of Sputum Among Tuberculosis Patients. Int Sch Res Notices. 2017;2017:7052583. PubMed PMID: 28781995.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Review of Organism Density and Bacteriologic Conversion of Sputum among Tuberculosis Patients. AU - Osei,Francis Adjei, AU - Enimil,Anthony, AU - Ansong,Daniel, AU - Laryea,Dennis Odai, AU - Mensah,Nicholas Karikari, AU - Amuzu,Evans Xorse, AU - Agyemang,Ebenezer Opambour, AU - Sarpong,Phans Oduro, AU - Nyanor,Isaac, AU - Dekugmen Yar,Denis, Y1 - 2017/07/11/ PY - 2017/03/23/received PY - 2017/06/01/revised PY - 2017/06/14/accepted PY - 2017/8/8/entrez PY - 2017/8/7/pubmed PY - 2017/8/7/medline SP - 7052583 EP - 7052583 JF - International scholarly research notices JO - Int Sch Res Notices VL - 2017 N2 - OBJECTIVE: This study sought to describe the trend of sputum organism density and the rate of bacteriological conversion among smear positive TB patients assessing care at the Komfo Anokye Teaching Hospital (KATH), Kumasi, Ghana. METHODS: We conducted a retrospective patient folder review from January 2013 to March 2016 at the KATH, a tertiary hospital in Ghana. The data was entered into Microsoft Access database and exported into STATA for analysis. We applied basic descriptive statistics to study variables. Sputum conversion rate (SCR) was estimated using the number of negative tests recorded over a period (numerator) and the number of patients reported in the same period (denominator) and expressed as a percentage. RESULTS: A total of 278 patient records with sputum smear positive at onset were studied. Before treatment sputum density detected in smear microscopy was as follows: 1 acid-fast bacillus (+) (n = 114), scanty (n = 19), ++ (n = 67), and +++ (n = 78). We recorded sputum conversion rate of 80.90%, 94.56%, and 98.31% in the intensive, continuation, and completion phases, respectively. CONCLUSION: This study has shown an increasing trend in sputum conversion of smear positive pulmonary tuberculosis and an increasing trend in loss to follow-ups among tuberculosis patients on treatment. SN - 2356-7872 UR - https://www.unboundmedicine.com/medline/citation/28781995/Review_of_Organism_Density_and_Bacteriologic_Conversion_of_Sputum_among_Tuberculosis_Patients L2 - https://dx.doi.org/10.1155/2017/7052583 DB - PRIME DP - Unbound Medicine ER -