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Factors predicting the self-evaluated health of hidradenitis suppurativa patients recruited from an outpatient clinic.
J Eur Acad Dermatol Venereol 2018; 32(2):313-317JE

Abstract

OBJECTIVES

In recent years, Hidradenitis suppurativa has received increased attention but still lack well-defined, robust patient-reported outcome measures. Such measures are likely to be influenced by contextual factors. We, therefore, aim to describe the association of biological and other factors with HS patient's self-evaluated health as reflected by the EQ5D VAS score.

METHODS

This cross-sectional study measured basic information, Dermatology Life Quality Index, Major Depression Inventory and Euro-QoL-5D. Information obtained through questionnaires was used to create a model showing the relation between biological factors, questionnaire results and self-evaluated health using the stepwise method for linear regression. Patients with HS (n = 805) registered at our department were invited to participate. A total of 503 (62.5%) patients replied to this survey. There was no difference in basic demographics between responders and non-responders.

RESULTS

Possible predictors for this study were DLQI, MDI, BMI, smoking, gender. A final model for correlation with self-evaluated health was obtained. Significant predictors for the model were DLQI (P < 0.05), BMI points above 25 and active smoking (both: P < 0.01) and MDI (P < 0.001).

CONCLUSION

As this is a cross-sectional study, it reveals several clinically relevant correlations. Smoking appears to correlate with the highest change in VAS score, but an MDI of 10 (lower than study average) or a BMI of 40 influences the results more. This study provides an assessment of how much BMI and smoking, in relation to other factors, correlate to the self-evaluated health state of patients with HS. These may, therefore, be relevant contextual factors to the construction and interpretation of specific patient-reported outcome measures. To improve QoL, we advocate smoking cessation and weight loss, and advice active screening for depression as over 10% of our patients qualify for a depressive diagnosis according to ICD-10.

Authors+Show Affiliations

Department of Dermatology, University Hospital Zealand, Roskilde, Denmark. Health Sciences Faculty, University of Copenhagen, Copenhagen, Denmark.Department of Dermatology, University Hospital Zealand, Roskilde, Denmark. Health Sciences Faculty, University of Copenhagen, Copenhagen, Denmark.Department of Dermatology, University Hospital Zealand, Roskilde, Denmark. Health Sciences Faculty, University of Copenhagen, Copenhagen, Denmark.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

28796910

Citation

Kjaersgaard Andersen, R, et al. "Factors Predicting the Self-evaluated Health of Hidradenitis Suppurativa Patients Recruited From an Outpatient Clinic." Journal of the European Academy of Dermatology and Venereology : JEADV, vol. 32, no. 2, 2018, pp. 313-317.
Kjaersgaard Andersen R, Theut Riis P, Jemec GBE. Factors predicting the self-evaluated health of hidradenitis suppurativa patients recruited from an outpatient clinic. J Eur Acad Dermatol Venereol. 2018;32(2):313-317.
Kjaersgaard Andersen, R., Theut Riis, P., & Jemec, G. B. E. (2018). Factors predicting the self-evaluated health of hidradenitis suppurativa patients recruited from an outpatient clinic. Journal of the European Academy of Dermatology and Venereology : JEADV, 32(2), pp. 313-317. doi:10.1111/jdv.14511.
Kjaersgaard Andersen R, Theut Riis P, Jemec GBE. Factors Predicting the Self-evaluated Health of Hidradenitis Suppurativa Patients Recruited From an Outpatient Clinic. J Eur Acad Dermatol Venereol. 2018;32(2):313-317. PubMed PMID: 28796910.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Factors predicting the self-evaluated health of hidradenitis suppurativa patients recruited from an outpatient clinic. AU - Kjaersgaard Andersen,R, AU - Theut Riis,P, AU - Jemec,G B E, Y1 - 2017/10/11/ PY - 2017/05/10/received PY - 2017/07/25/accepted PY - 2017/8/11/pubmed PY - 2018/9/6/medline PY - 2017/8/11/entrez SP - 313 EP - 317 JF - Journal of the European Academy of Dermatology and Venereology : JEADV JO - J Eur Acad Dermatol Venereol VL - 32 IS - 2 N2 - OBJECTIVES: In recent years, Hidradenitis suppurativa has received increased attention but still lack well-defined, robust patient-reported outcome measures. Such measures are likely to be influenced by contextual factors. We, therefore, aim to describe the association of biological and other factors with HS patient's self-evaluated health as reflected by the EQ5D VAS score. METHODS: This cross-sectional study measured basic information, Dermatology Life Quality Index, Major Depression Inventory and Euro-QoL-5D. Information obtained through questionnaires was used to create a model showing the relation between biological factors, questionnaire results and self-evaluated health using the stepwise method for linear regression. Patients with HS (n = 805) registered at our department were invited to participate. A total of 503 (62.5%) patients replied to this survey. There was no difference in basic demographics between responders and non-responders. RESULTS: Possible predictors for this study were DLQI, MDI, BMI, smoking, gender. A final model for correlation with self-evaluated health was obtained. Significant predictors for the model were DLQI (P < 0.05), BMI points above 25 and active smoking (both: P < 0.01) and MDI (P < 0.001). CONCLUSION: As this is a cross-sectional study, it reveals several clinically relevant correlations. Smoking appears to correlate with the highest change in VAS score, but an MDI of 10 (lower than study average) or a BMI of 40 influences the results more. This study provides an assessment of how much BMI and smoking, in relation to other factors, correlate to the self-evaluated health state of patients with HS. These may, therefore, be relevant contextual factors to the construction and interpretation of specific patient-reported outcome measures. To improve QoL, we advocate smoking cessation and weight loss, and advice active screening for depression as over 10% of our patients qualify for a depressive diagnosis according to ICD-10. SN - 1468-3083 UR - https://www.unboundmedicine.com/medline/citation/28796910/Factors_predicting_the_self_evaluated_health_of_hidradenitis_suppurativa_patients_recruited_from_an_outpatient_clinic_ L2 - https://doi.org/10.1111/jdv.14511 DB - PRIME DP - Unbound Medicine ER -