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Necrotizing Infundibular Crystalline Folliculitis: An Unusual Clinical Presentation and Demonstration of the Presence of Calcium Palmitate.
Am J Dermatopathol. 2018 Jan; 40(1):e9-e11.AJ

Abstract

Necrotizing infundibular crystalline folliculitis (NICF) is a rare disorder, which was described for the first time by Lucke et al in 1999. NICF is characterized by multiple folliculocentric papules with a predilection for occurring in seborrheic areas in adults and corresponding dilated follicular ostia containing crystalline material. The precise pathogenesis and nature of this crystalline material are currently unknown. Here, we report an unusual case of NICF presented as an uncommon generalized skin rash in an adolescent. In addition, we present analysis using infrared microscopy for improved characterization of this crystalline material. Similar to previous cases, a biopsy revealed a dilated follicular ostium with the appearance of containing crystalline material associated with parakeratosis. Infrared microscopy analysis produced specific spectral features of calcium palmitate.

Authors+Show Affiliations

Department of Pathology, Necker-Enfants Malades Hospital, APHP, Paris, France.Cabinet de Dermatologie, Guyancourt, France.Laboratoire des Lithiases, Service des Explorations Fonctionnelles, Tenon Hospital, APHP, Paris, France.Department of Pathology, Necker-Enfants Malades Hospital, APHP, Paris, France. Université Paris Descartes, Sorbonne Paris Cité, Paris, France.Laboratoire des Lithiases, Service des Explorations Fonctionnelles, Tenon Hospital, APHP, Paris, France.Department of Pathology, Necker-Enfants Malades Hospital, APHP, Paris, France.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

28816737

Citation

Beaufrère, Aurélie, et al. "Necrotizing Infundibular Crystalline Folliculitis: an Unusual Clinical Presentation and Demonstration of the Presence of Calcium Palmitate." The American Journal of Dermatopathology, vol. 40, no. 1, 2018, pp. e9-e11.
Beaufrère A, Garcia V, Frochot V, et al. Necrotizing Infundibular Crystalline Folliculitis: An Unusual Clinical Presentation and Demonstration of the Presence of Calcium Palmitate. Am J Dermatopathol. 2018;40(1):e9-e11.
Beaufrère, A., Garcia, V., Frochot, V., Molina, T., Daudon, M., & Fraitag, S. (2018). Necrotizing Infundibular Crystalline Folliculitis: An Unusual Clinical Presentation and Demonstration of the Presence of Calcium Palmitate. The American Journal of Dermatopathology, 40(1), e9-e11. https://doi.org/10.1097/DAD.0000000000000964
Beaufrère A, et al. Necrotizing Infundibular Crystalline Folliculitis: an Unusual Clinical Presentation and Demonstration of the Presence of Calcium Palmitate. Am J Dermatopathol. 2018;40(1):e9-e11. PubMed PMID: 28816737.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Necrotizing Infundibular Crystalline Folliculitis: An Unusual Clinical Presentation and Demonstration of the Presence of Calcium Palmitate. AU - Beaufrère,Aurélie, AU - Garcia,Valérie, AU - Frochot,Vincent, AU - Molina,Thierry, AU - Daudon,Michel, AU - Fraitag,Sylvie, PY - 2017/8/18/pubmed PY - 2018/8/7/medline PY - 2017/8/18/entrez SP - e9 EP - e11 JF - The American Journal of dermatopathology JO - Am J Dermatopathol VL - 40 IS - 1 N2 - Necrotizing infundibular crystalline folliculitis (NICF) is a rare disorder, which was described for the first time by Lucke et al in 1999. NICF is characterized by multiple folliculocentric papules with a predilection for occurring in seborrheic areas in adults and corresponding dilated follicular ostia containing crystalline material. The precise pathogenesis and nature of this crystalline material are currently unknown. Here, we report an unusual case of NICF presented as an uncommon generalized skin rash in an adolescent. In addition, we present analysis using infrared microscopy for improved characterization of this crystalline material. Similar to previous cases, a biopsy revealed a dilated follicular ostium with the appearance of containing crystalline material associated with parakeratosis. Infrared microscopy analysis produced specific spectral features of calcium palmitate. SN - 1533-0311 UR - https://www.unboundmedicine.com/medline/citation/28816737/Necrotizing_Infundibular_Crystalline_Folliculitis:_An_Unusual_Clinical_Presentation_and_Demonstration_of_the_Presence_of_Calcium_Palmitate_ L2 - https://doi.org/10.1097/DAD.0000000000000964 DB - PRIME DP - Unbound Medicine ER -