Identification and structural characterisation of triterpene saponins from the root of Ardisia mamillata Hance by HPLC-ESI-QTOF-MS/MS.
Nat Prod Res. 2018 Apr; 32(8):918-923.NP

Abstract

Triterpene saponins in medicinal plants attract scientific attentions for their structural diversity and significant bioactivities. In this work, a high-performance liquid chromatography coupled to electrospray ionisation and quadrupole time-of-flight mass spectrometry (HPLC-ESI-QTOF-MS/MS) method is used to rapidly separate and identify triterpene saponins from the extract of Ardisia mamillata Hance (AMH). In the full scan mass spectrum, the accurate determination of molecular formula is obtained by the predominant ion [M + HCOO]- in negative ion mode. As a result, 30 triterpene saponins are identified or tentatively identified in the plant extract. Of these, 17 triterpene saponins are new compounds. In conclusion, the HPLC-ESI-QTOF-MS/MS is an efficient technique to separate and identify triterpene saponins in complex matrices of medicinal plant.

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Authors+Show Affiliations

Zhang EF

a Institute of Pharmaceutical Engineering , Jiangsu Food & Pharmaceutical Science College , Huaian , China.

Ling Y

b Department of Pharmaceutical and Life Sciences , Jiujiang University , Jiujiang , China.

Yin Z

c Department of Inspection and Pharmacy , Jiang Su College of Nursing , Huaian , China.

Zhang Q

b Department of Pharmaceutical and Life Sciences , Jiujiang University , Jiujiang , China.

MeSH

ArdisiaChromatography, High Pressure LiquidMolecular StructurePlant ExtractsPlant RootsPlants, MedicinalSaponinsSpectrometry, Mass, Electrospray IonizationTandem Mass SpectrometryTriterpenes

Pub Type(s)

Journal Article

Language

eng

PubMed ID

28830240

Citation

Zhang, Er-Fei, et al. "Identification and Structural Characterisation of Triterpene Saponins From the Root of Ardisia Mamillata Hance By HPLC-ESI-QTOF-MS/MS." Natural Product Research, vol. 32, no. 8, 2018, pp. 918-923.

Zhang EF, Ling Y, Yin Z, et al. Identification and structural characterisation of triterpene saponins from the root of Ardisia mamillata Hance by HPLC-ESI-QTOF-MS/MS. Nat Prod Res. 2018;32(8):918-923.

Zhang, E. F., Ling, Y., Yin, Z., & Zhang, Q. (2018). Identification and structural characterisation of triterpene saponins from the root of Ardisia mamillata Hance by HPLC-ESI-QTOF-MS/MS. Natural Product Research, 32(8), 918-923. https://doi.org/10.1080/14786419.2017.1367787

Zhang EF, et al. Identification and Structural Characterisation of Triterpene Saponins From the Root of Ardisia Mamillata Hance By HPLC-ESI-QTOF-MS/MS. Nat Prod Res. 2018;32(8):918-923. PubMed PMID: 28830240.

* Article titles in AMA citation format should be in sentence-case

TY - JOUR T1 - Identification and structural characterisation of triterpene saponins from the root of Ardisia mamillata Hance by HPLC-ESI-QTOF-MS/MS. AU - Zhang,Er-Fei, AU - Ling,Yun, AU - Yin,Zi, AU - Zhang,Qing, Y1 - 2017/08/22/ PY - 2017/8/24/pubmed PY - 2018/4/18/medline PY - 2017/8/24/entrez KW - Ardisia mamillata Hance KW - HPLC-ESI-QTOF-MS/MS KW - triterpene saponins SP - 918 EP - 923 JF - Natural product research JO - Nat Prod Res VL - 32 IS - 8 N2 - Triterpene saponins in medicinal plants attract scientific attentions for their structural diversity and significant bioactivities. In this work, a high-performance liquid chromatography coupled to electrospray ionisation and quadrupole time-of-flight mass spectrometry (HPLC-ESI-QTOF-MS/MS) method is used to rapidly separate and identify triterpene saponins from the extract of Ardisia mamillata Hance (AMH). In the full scan mass spectrum, the accurate determination of molecular formula is obtained by the predominant ion [M + HCOO]- in negative ion mode. As a result, 30 triterpene saponins are identified or tentatively identified in the plant extract. Of these, 17 triterpene saponins are new compounds. In conclusion, the HPLC-ESI-QTOF-MS/MS is an efficient technique to separate and identify triterpene saponins in complex matrices of medicinal plant. SN - 1478-6427 UR - https://www.unboundmedicine.com/medline/citation/28830240/Identification_and_structural_characterisation_of_triterpene_saponins_from_the_root_of_Ardisia_mamillata_Hance_by_HPLC_ESI_QTOF_MS/MS_ L2 - https://www.tandfonline.com/doi/full/10.1080/14786419.2017.1367787 DB - PRIME DP - Unbound Medicine ER -

Tags

Identification and structural characterisation of triterpene saponins from the root of Ardisia mamillata Hance by HPLC-ESI-QTOF-MS/MS.Nat Prod Res. 2018 Apr; 32(8):918-923.NP