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Imported case of Middle East respiratory syndrome coronavirus (MERS-CoV) infection from Oman to Thailand, June 2015.
Euro Surveill. 2017 Aug 17; 22(33)ES

Abstract

Thailand reported the first Middle East respiratory syndrome (MERS) case on 18 June 2015 (day 4) in an Omani patient with heart condition who was diagnosed with pneumonia on hospital admission on 15 June 2015 (day 1). Two false negative RT-PCR on upper respiratory tract samples on days 2 and 3 led to a 48-hour diagnosis delay and a decision to transfer the patient out of the negative pressure unit (NPU). Subsequent examination of sputum later on day 3 confirmed MERS coronavirus (MERS-CoV) infection. The patient was immediately moved back into the NPU and then transferred to Bamrasnaradura Infectious Disease Institute. Over 170 contacts were traced; 48 were quarantined and 122 self-monitored for symptoms. High-risk close contacts exhibiting no symptoms, and whose laboratory testing on the 12th day after exposure was negative, were released on the 14th day. The Omani Ministry of Health (MOH) was immediately notified using the International Health Regulation (IHR) mechanism. Outbreak investigation was conducted in Oman, and was both published on the World Health Organization (WHO) intranet and shared with Thailand's IHR focal point. The key to successful infection control, with no secondary transmission, were the collaborative efforts among hospitals, laboratories and MOHs of both countries.

Authors+Show Affiliations

Bureau of Epidemiology, Department of Disease Control, Ministry of Public Health, Nonthaburi, Thailand.Bureau of Epidemiology, Department of Disease Control, Ministry of Public Health, Nonthaburi, Thailand.World Health Organization Collaborating Centre for Research and Training on Viral Zoonoses, King Chulalongkorn Memorial Hospital, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.Bureau of Epidemiology, Department of Disease Control, Ministry of Public Health, Nonthaburi, Thailand.Bureau of Epidemiology, Department of Disease Control, Ministry of Public Health, Nonthaburi, Thailand.Bamrasnaradura Infectious Diseases Institute, Department of Disease Control, Ministry of Public Health, Nonthaburi, Thailand.World Health Organization Collaborating Centre for Research and Training on Viral Zoonoses, King Chulalongkorn Memorial Hospital, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.World Health Organization Collaborating Centre for Research and Training on Viral Zoonoses, King Chulalongkorn Memorial Hospital, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.World Health Organization Collaborating Centre for Research and Training on Viral Zoonoses, King Chulalongkorn Memorial Hospital, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.World Health Organization Collaborating Centre for Research and Training on Viral Zoonoses, King Chulalongkorn Memorial Hospital, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.World Health Organization Collaborating Centre for Research and Training on Viral Zoonoses, King Chulalongkorn Memorial Hospital, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.World Health Organization Collaborating Centre for Research and Training on Viral Zoonoses, King Chulalongkorn Memorial Hospital, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.World Health Organization Collaborating Centre for Research and Training on Viral Zoonoses, King Chulalongkorn Memorial Hospital, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.World Health Organization Collaborating Centre for Research and Training on Viral Zoonoses, King Chulalongkorn Memorial Hospital, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. Department of Microbiology and Immunology, Faculty of Tropical Medicine Mahidol University, Bangkok, Thailand.Institute of Molecular Biosciences, Mahidol University, Bangkok, Thailand.Institute of Molecular Biosciences, Mahidol University, Bangkok, Thailand.Institute of Virology, University of Bonn Medical Centre, Bonn, Germany. German Centre for Infection Research, Partner Site Bonn-Cologne, Bonn, Germany.Institute of Virology, University of Bonn Medical Centre, Bonn, Germany. German Centre for Infection Research, Partner Site Bonn-Cologne, Bonn, Germany.World Health Organization Collaborating Centre for Research and Training on Viral Zoonoses, King Chulalongkorn Memorial Hospital, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

28840828

Citation

Plipat, Tanarak, et al. "Imported Case of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Infection From Oman to Thailand, June 2015." Euro Surveillance : Bulletin Europeen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin, vol. 22, no. 33, 2017.
Plipat T, Buathong R, Wacharapluesadee S, et al. Imported case of Middle East respiratory syndrome coronavirus (MERS-CoV) infection from Oman to Thailand, June 2015. Euro Surveill. 2017;22(33).
Plipat, T., Buathong, R., Wacharapluesadee, S., Siriarayapon, P., Pittayawonganon, C., Sangsajja, C., Kaewpom, T., Petcharat, S., Ponpinit, T., Jumpasri, J., Joyjinda, Y., Rodpan, A., Ghai, S., Jittmittraphap, A., Khongwichit, S., Smith, D. R., Corman, V. M., Drosten, C., & Hemachudha, T. (2017). Imported case of Middle East respiratory syndrome coronavirus (MERS-CoV) infection from Oman to Thailand, June 2015. Euro Surveillance : Bulletin Europeen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin, 22(33). https://doi.org/10.2807/1560-7917.ES.2017.22.33.30598
Plipat T, et al. Imported Case of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Infection From Oman to Thailand, June 2015. Euro Surveill. 2017 Aug 17;22(33) PubMed PMID: 28840828.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Imported case of Middle East respiratory syndrome coronavirus (MERS-CoV) infection from Oman to Thailand, June 2015. AU - Plipat,Tanarak, AU - Buathong,Rome, AU - Wacharapluesadee,Supaporn, AU - Siriarayapon,Potjaman, AU - Pittayawonganon,Chakrarat, AU - Sangsajja,Chariya, AU - Kaewpom,Thongchai, AU - Petcharat,Sininat, AU - Ponpinit,Teerada, AU - Jumpasri,Jaruphan, AU - Joyjinda,Yutthana, AU - Rodpan,Apaporn, AU - Ghai,Siriporn, AU - Jittmittraphap,Akanitt, AU - Khongwichit,Sarawut, AU - Smith,Duncan R, AU - Corman,Victor M, AU - Drosten,Christian, AU - Hemachudha,Thiravat, PY - 2016/08/24/received PY - 2017/02/08/accepted PY - 2017/8/26/entrez PY - 2017/8/26/pubmed PY - 2018/3/7/medline KW - MERS KW - MERS-CoV KW - Thailand KW - contact tracing KW - diagnostic KW - imported case JF - Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin JO - Euro Surveill VL - 22 IS - 33 N2 - Thailand reported the first Middle East respiratory syndrome (MERS) case on 18 June 2015 (day 4) in an Omani patient with heart condition who was diagnosed with pneumonia on hospital admission on 15 June 2015 (day 1). Two false negative RT-PCR on upper respiratory tract samples on days 2 and 3 led to a 48-hour diagnosis delay and a decision to transfer the patient out of the negative pressure unit (NPU). Subsequent examination of sputum later on day 3 confirmed MERS coronavirus (MERS-CoV) infection. The patient was immediately moved back into the NPU and then transferred to Bamrasnaradura Infectious Disease Institute. Over 170 contacts were traced; 48 were quarantined and 122 self-monitored for symptoms. High-risk close contacts exhibiting no symptoms, and whose laboratory testing on the 12th day after exposure was negative, were released on the 14th day. The Omani Ministry of Health (MOH) was immediately notified using the International Health Regulation (IHR) mechanism. Outbreak investigation was conducted in Oman, and was both published on the World Health Organization (WHO) intranet and shared with Thailand's IHR focal point. The key to successful infection control, with no secondary transmission, were the collaborative efforts among hospitals, laboratories and MOHs of both countries. SN - 1560-7917 UR - https://www.unboundmedicine.com/medline/citation/28840828/Imported_case_of_Middle_East_respiratory_syndrome_coronavirus__MERS_CoV__infection_from_Oman_to_Thailand_June_2015_ L2 - http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=22860 DB - PRIME DP - Unbound Medicine ER -