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Disparities in hypertension and cardiovascular disease in blacks: The critical role of medication adherence.
J Clin Hypertens (Greenwich). 2017 Oct; 19(10):1015-1024.JC

Abstract

Blacks are two to three times as likely as whites to die of preventable heart disease and stroke. Declines in mortality from heart disease have not eliminated racial disparities. Control and effective treatment of hypertension, a leading cause of cardiovascular disease, among blacks is less than in whites and remains a challenge. One of the driving forces behind this racial/ethnic disparity is medication nonadherence whose cause is embedded in social determinants. Eight practical approaches to addressing medication adherence with the potential to attenuate disparities were identified and include: (1) patient engagement strategies, (2) consumer-directed health care, (3) patient portals, (4) smart apps and text messages, (5) digital pillboxes, (6) pharmacist-led engagement, (7) cardiac rehabilitation, and (8) cognitive-based behavior. However, while data suggest that these strategies may improve medication adherence, the effect on ameliorating racial/ethnic disparities is not certain. This review describes the relationship between disparities and medication adherence, which likely plays a role in persistent disparities in cardiovascular morbidity and mortality.

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Authors+Show Affiliations

Ferdinand KC
Tulane Heart and Vascular Institute, Tulane University School of Medicine, New Orleans, LA, USA.
Yadav K
Tulane Heart and Vascular Institute, Tulane University School of Medicine, New Orleans, LA, USA.
Nasser SA
Department of Clinical Research & Leadership, School of Medicine and Health Sciences, The George Washington University, Washington, DC, USA.
Clayton-Jeter HD
Cardiovascular and Endocrine Liaison Program, Office of the Commissioner/External Affairs/Health & Constituent Affairs, Food and Drug Administration, Silver Springs, MD, USA.
Lewin J
Lewin and Associates LLC, National Coalition on Health Care, Washington, DC, USA.
Cryer DR
CryerHealth, Washington, DC, USA.
Senatore FF
Center for Drug Evaluation Research, Food and Drug Administration, Silver Springs, MD, USA.

MeSH

African AmericansAntihypertensive AgentsAwarenessCardiovascular DiseasesFemaleHealthcare DisparitiesHispanic or LatinoHumansHypertensionMaleMedication AdherenceRetrospective StudiesSocial ClassUnited StatesWhites

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

28856834

Citation

Ferdinand, Keith C., et al. "Disparities in Hypertension and Cardiovascular Disease in Blacks: the Critical Role of Medication Adherence." Journal of Clinical Hypertension (Greenwich, Conn.), vol. 19, no. 10, 2017, pp. 1015-1024.
Ferdinand KC, Yadav K, Nasser SA, et al. Disparities in hypertension and cardiovascular disease in blacks: The critical role of medication adherence. J Clin Hypertens (Greenwich). 2017;19(10):1015-1024.
Ferdinand, K. C., Yadav, K., Nasser, S. A., Clayton-Jeter, H. D., Lewin, J., Cryer, D. R., & Senatore, F. F. (2017). Disparities in hypertension and cardiovascular disease in blacks: The critical role of medication adherence. Journal of Clinical Hypertension (Greenwich, Conn.), 19(10), 1015-1024. https://doi.org/10.1111/jch.13089
Ferdinand KC, et al. Disparities in Hypertension and Cardiovascular Disease in Blacks: the Critical Role of Medication Adherence. J Clin Hypertens (Greenwich). 2017;19(10):1015-1024. PubMed PMID: 28856834.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Disparities in hypertension and cardiovascular disease in blacks: The critical role of medication adherence. AU - Ferdinand,Keith C, AU - Yadav,Kapil, AU - Nasser,Samar A, AU - Clayton-Jeter,Helene D, AU - Lewin,John, AU - Cryer,Dennis R, AU - Senatore,Fortunato Fred, Y1 - 2017/08/30/ PY - 2017/03/19/received PY - 2017/05/21/revised PY - 2017/05/22/accepted PY - 2017/9/1/pubmed PY - 2018/6/14/medline PY - 2017/9/1/entrez KW - Adherence KW - Food and Drug Administration KW - blacks KW - cardiovascular disease KW - health disparities KW - hypertension KW - race/ethnicity SP - 1015 EP - 1024 JF - Journal of clinical hypertension (Greenwich, Conn.) JO - J Clin Hypertens (Greenwich) VL - 19 IS - 10 N2 - Blacks are two to three times as likely as whites to die of preventable heart disease and stroke. Declines in mortality from heart disease have not eliminated racial disparities. Control and effective treatment of hypertension, a leading cause of cardiovascular disease, among blacks is less than in whites and remains a challenge. One of the driving forces behind this racial/ethnic disparity is medication nonadherence whose cause is embedded in social determinants. Eight practical approaches to addressing medication adherence with the potential to attenuate disparities were identified and include: (1) patient engagement strategies, (2) consumer-directed health care, (3) patient portals, (4) smart apps and text messages, (5) digital pillboxes, (6) pharmacist-led engagement, (7) cardiac rehabilitation, and (8) cognitive-based behavior. However, while data suggest that these strategies may improve medication adherence, the effect on ameliorating racial/ethnic disparities is not certain. This review describes the relationship between disparities and medication adherence, which likely plays a role in persistent disparities in cardiovascular morbidity and mortality. SN - 1751-7176 UR - https://www.unboundmedicine.com/medline/citation/28856834/full_citation L2 - https://doi.org/10.1111/jch.13089 DB - PRIME DP - Unbound Medicine ER -