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Could Pomegranate Juice Help in the Control of Inflammatory Diseases?
Nutrients. 2017 Aug 30; 9(9)N

Abstract

Fruits rich in polyphenols, such as pomegranates, have been shown to have health benefits relating to their antioxidant and anti-inflammatory properties. Using data obtained from PubMed and Scopus, this article provides a brief overview of the therapeutic effects of pomegranate on chronic inflammatory diseases (CID) such as inflammatory bowel disease (IBD), rheumatoid arthritis (RA), metabolic and cardiovascular disorders, and other inflammatory-associated conditions, with an emphasis on fruit-derived juices. Most studies regarding the effects of pomegranate juice have focused on its ability to treat prostate cancer, diabetes, and atherosclerosis. However, pomegranate juice has shown therapeutic potential for many other illnesses. For instance, a small number of human clinical trials have highlighted the positive effects of pomegranate juice and extract consumption on cardiovascular health. The beneficial effects of pomegranate components have also been observed in animal models for respiratory diseases, RA, neurodegenerative disease, and hyperlipidaemia. Furthermore, there exists strong evidence from rodent models suggesting that pomegranate juice can be used to effectively treat IBD, and as an anti-inflammatory agent to treat CID. The effects of pomegranate intake should be further investigated by conducting larger and more well-defined human trials.

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Authors+Show Affiliations

Danesi F
Department of Agri-Food Science and Technology (DISTAL), University of Bologna, Piazza Goidanich 60, 47521 Cesena, Italy. francesca.danesi@unibo.it.
Ferguson LR
Discipline of Nutrition and Dietetics, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand. l.ferguson@auckland.ac.nz.

MeSH

AnimalsAntioxidantsFruit and Vegetable JuicesHumansInflammationLythraceaePlant ExtractsPolyphenols

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

28867799

Citation

Danesi, Francesca, and Lynnette R. Ferguson. "Could Pomegranate Juice Help in the Control of Inflammatory Diseases?" Nutrients, vol. 9, no. 9, 2017.
Danesi F, Ferguson LR. Could Pomegranate Juice Help in the Control of Inflammatory Diseases? Nutrients. 2017;9(9).
Danesi, F., & Ferguson, L. R. (2017). Could Pomegranate Juice Help in the Control of Inflammatory Diseases? Nutrients, 9(9). https://doi.org/10.3390/nu9090958
Danesi F, Ferguson LR. Could Pomegranate Juice Help in the Control of Inflammatory Diseases. Nutrients. 2017 Aug 30;9(9) PubMed PMID: 28867799.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Could Pomegranate Juice Help in the Control of Inflammatory Diseases? AU - Danesi,Francesca, AU - Ferguson,Lynnette R, Y1 - 2017/08/30/ PY - 2017/07/30/received PY - 2017/08/19/revised PY - 2017/08/26/accepted PY - 2017/9/5/entrez PY - 2017/9/5/pubmed PY - 2018/5/15/medline KW - Punica granatum KW - anti-inflammatory properties KW - ellagitannins KW - inflammation KW - inflammatory diseases KW - pomegranate KW - pomegranate juice JF - Nutrients JO - Nutrients VL - 9 IS - 9 N2 - Fruits rich in polyphenols, such as pomegranates, have been shown to have health benefits relating to their antioxidant and anti-inflammatory properties. Using data obtained from PubMed and Scopus, this article provides a brief overview of the therapeutic effects of pomegranate on chronic inflammatory diseases (CID) such as inflammatory bowel disease (IBD), rheumatoid arthritis (RA), metabolic and cardiovascular disorders, and other inflammatory-associated conditions, with an emphasis on fruit-derived juices. Most studies regarding the effects of pomegranate juice have focused on its ability to treat prostate cancer, diabetes, and atherosclerosis. However, pomegranate juice has shown therapeutic potential for many other illnesses. For instance, a small number of human clinical trials have highlighted the positive effects of pomegranate juice and extract consumption on cardiovascular health. The beneficial effects of pomegranate components have also been observed in animal models for respiratory diseases, RA, neurodegenerative disease, and hyperlipidaemia. Furthermore, there exists strong evidence from rodent models suggesting that pomegranate juice can be used to effectively treat IBD, and as an anti-inflammatory agent to treat CID. The effects of pomegranate intake should be further investigated by conducting larger and more well-defined human trials. SN - 2072-6643 UR - https://www.unboundmedicine.com/medline/citation/28867799/Could_Pomegranate_Juice_Help_in_the_Control_of_Inflammatory_Diseases DB - PRIME DP - Unbound Medicine ER -