Tags

Type your tag names separated by a space and hit enter

Acute diffuse peritonitis due to spontaneous rupture of a primary gastrointestinal stromal tumor of the jejunum: A case report.
Int J Surg Case Rep. 2017; 39:288-292.IJ

Abstract

INTRODUCTION

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. Overt peritonitis caused by GIST rupture is very uncommon. Three types of GIST rupture have been described: closed perforation due to abscess (abscess type), hemoperitoneum leading to rupture of the hematoma capsule in the tumor (hemoperitoneum type), and perforation of the digestive tract via a fistula leading to central necrosis of the tumor (bowel perforation type). This report describes a patient with spontaneous tumor rupture and diffuse peritonitis, a variant of the bowel perforation type of GIST rupture.

PRESENTATION OF CASE

A 74-year-old man presented with symptoms of vomiting and abdominal pain. Computed tomography (CT) scan revealed an approximately 10×7-cm mass in the pelvis with free air and fluid collection. Emergency laparotomy revealed a tumor in the jejunum, which was ruptured with a hole measuring 5mm in diameter. The tumor and part of the jejunum were resected. Immunohistochemically, the mass was diagnosed as a GIST originating from the gastrointestinal tract. Despite chemotherapy with imatinib mesylate, the patient died 22 months after surgery.

CONCLUSIONS

This report describes a patient with acute diffuse peritonitis due to spontaneous rupture of a primary GIST of the jejunum.

Authors+Show Affiliations

Department of Surgery, Chugoku Rosai Hospital, 1-5-1, Tagaya, Hiro, Kure City, Hiroshima 737-0193, Japan.Department of Surgery, Kure Medical Center, National Hospital Organization, 3-1 Aoyama, Kure City, Hiroshima 737-0023, Japan. Electronic address: thiroes@gmail.com.Department of Surgery, Chugoku Rosai Hospital, 1-5-1, Tagaya, Hiro, Kure City, Hiroshima 737-0193, Japan.Department of Surgery, Chugoku Rosai Hospital, 1-5-1, Tagaya, Hiro, Kure City, Hiroshima 737-0193, Japan.Department of Surgery, Chugoku Rosai Hospital, 1-5-1, Tagaya, Hiro, Kure City, Hiroshima 737-0193, Japan.Department of Surgery, Chugoku Rosai Hospital, 1-5-1, Tagaya, Hiro, Kure City, Hiroshima 737-0193, Japan.Department of Surgery, Chugoku Rosai Hospital, 1-5-1, Tagaya, Hiro, Kure City, Hiroshima 737-0193, Japan.Department of Surgery, Chugoku Rosai Hospital, 1-5-1, Tagaya, Hiro, Kure City, Hiroshima 737-0193, Japan.Department of Internal Medicine, Chugoku Rosai Hospital, 1-5-1, Tagaya, Hiro, Kure City, Hiroshima 737-0193, Japan.Department of Diagnostic Pathology, Chugoku Rosai Hospital, 1-5-1, Tagaya, Hiro, Kure City, Hiroshima 737-0193, Japan.Department of Gastroenterological and Transplant Surgery, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima 734-8551, Japan.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

28888914

Citation

Sato, Koki, et al. "Acute Diffuse Peritonitis Due to Spontaneous Rupture of a Primary Gastrointestinal Stromal Tumor of the Jejunum: a Case Report." International Journal of Surgery Case Reports, vol. 39, 2017, pp. 288-292.
Sato K, Tazawa H, Fujisaki S, et al. Acute diffuse peritonitis due to spontaneous rupture of a primary gastrointestinal stromal tumor of the jejunum: A case report. International journal of surgery case reports. 2017;39:288-292.
Sato, K., Tazawa, H., Fujisaki, S., Fukuhara, S., Imaoka, K., Hirata, Y., Takahashi, M., Fukuda, S., Kuga, Y., Nishida, T., & Sakimoto, H. (2017). Acute diffuse peritonitis due to spontaneous rupture of a primary gastrointestinal stromal tumor of the jejunum: A case report. International Journal of Surgery Case Reports, 39, 288-292. https://doi.org/10.1016/j.ijscr.2017.08.041
Sato K, et al. Acute Diffuse Peritonitis Due to Spontaneous Rupture of a Primary Gastrointestinal Stromal Tumor of the Jejunum: a Case Report. International journal of surgery case reports. 2017;39:288-292. PubMed PMID: 28888914.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Acute diffuse peritonitis due to spontaneous rupture of a primary gastrointestinal stromal tumor of the jejunum: A case report. AU - Sato,Koki, AU - Tazawa,Hirofumi, AU - Fujisaki,Seiji, AU - Fukuhara,Sotaro, AU - Imaoka,Koki, AU - Hirata,Yuzo, AU - Takahashi,Mamoru, AU - Fukuda,Saburo, AU - Kuga,Yoshio, AU - Nishida,Toshihiro, AU - Sakimoto,Hideto, Y1 - 2017/08/23/ PY - 2017/07/10/received PY - 2017/08/18/revised PY - 2017/08/18/accepted PY - 2017/9/11/pubmed PY - 2017/9/11/medline PY - 2017/9/11/entrez KW - Gastrointestinal stromal tumor (GIST) KW - Small bowel KW - Tumor perforation SP - 288 EP - 292 JF - International journal of surgery case reports VL - 39 N2 - INTRODUCTION: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. Overt peritonitis caused by GIST rupture is very uncommon. Three types of GIST rupture have been described: closed perforation due to abscess (abscess type), hemoperitoneum leading to rupture of the hematoma capsule in the tumor (hemoperitoneum type), and perforation of the digestive tract via a fistula leading to central necrosis of the tumor (bowel perforation type). This report describes a patient with spontaneous tumor rupture and diffuse peritonitis, a variant of the bowel perforation type of GIST rupture. PRESENTATION OF CASE: A 74-year-old man presented with symptoms of vomiting and abdominal pain. Computed tomography (CT) scan revealed an approximately 10×7-cm mass in the pelvis with free air and fluid collection. Emergency laparotomy revealed a tumor in the jejunum, which was ruptured with a hole measuring 5mm in diameter. The tumor and part of the jejunum were resected. Immunohistochemically, the mass was diagnosed as a GIST originating from the gastrointestinal tract. Despite chemotherapy with imatinib mesylate, the patient died 22 months after surgery. CONCLUSIONS: This report describes a patient with acute diffuse peritonitis due to spontaneous rupture of a primary GIST of the jejunum. SN - 2210-2612 UR - https://www.unboundmedicine.com/medline/citation/28888914/Acute_diffuse_peritonitis_due_to_spontaneous_rupture_of_a_primary_gastrointestinal_stromal_tumor_of_the_jejunum:_A_case_report_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S2210-2612(17)30433-9 DB - PRIME DP - Unbound Medicine ER -