TY - JOUR T1 - Treatment of erythemato-telangiectatic rosacea with brimonidine alone or combined with vascular laser based on preliminary instrumental evaluation of the vascular component. AU - Micali,Giuseppe, AU - Dall'Oglio,Federica, AU - Verzì,Anna Elisa, AU - Luppino,Ivano, AU - Bhatt,Karishma, AU - Lacarrubba,Francesco, Y1 - 2017/09/09/ PY - 2016/12/21/received PY - 2017/08/28/accepted PY - 2017/9/11/pubmed PY - 2018/8/18/medline PY - 2017/9/11/entrez KW - Brimonidine KW - Dermoscopy KW - Digital photography KW - Rosacea KW - Treatment KW - Vascular laser SP - 1397 EP - 1400 JF - Lasers in medical science JO - Lasers Med Sci VL - 33 IS - 6 N2 - The purpose of this study is to evaluate the outcome of a series of patients with erythematotelangiectatic rosacea (ETR) affected by persistent erythema and varying degree of telangiectasias being treated with brimonidine alone or combined with a vascular laser based on the type of vascular components preliminarily evaluated by clinical and instrumental observation. Ten patients affected by ETR were enrolled in a pilot, open study. Instrumental evaluation included erythema-directed digital photography by VISIA-CR™ system and X10 dermoscopy. Those patients showing marked background erythema and minimal telangiectasias (group A) were treated with a single application of brimonidine 0.33% gel, while patients showing both marked background erythema and marked telangiectasias (group B) were treated with a session of Nd:YAG laser and reevaluated 1 month later after a single application of brimonidine. An Investigator Global Assessment (IGA) of treatment outcome was performed at the end of treatment in both groups. In group A, 6 h after brimonidine application, a marked reduction of the background erythema was observed in all patients, and IGA was rated as excellent. In group B, 6 h following the application of brimonidine, a marked reduction of the background erythema was observed in all cases, while telangiectasias remained unchanged. A further treatment with brimonidine 1 month after the Nd:YAG laser session determined complete clearing of facial erythema, and IGA was rated as excellent. In conclusion, a preliminary evaluation of the vascular component by erythema-directed digital photography and dermoscopy in ETR may be helpful to select the most appropriate therapeutic strategy. SN - 1435-604X UR - https://www.unboundmedicine.com/medline/citation/28889348/Treatment_of_erythemato_telangiectatic_rosacea_with_brimonidine_alone_or_combined_with_vascular_laser_based_on_preliminary_instrumental_evaluation_of_the_vascular_component_ DB - PRIME DP - Unbound Medicine ER -