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The Incidence and Prevalence of Systemic Lupus Erythematosus in San Francisco County, California: The California Lupus Surveillance Project.
Arthritis Rheumatol 2017; 69(10):1996-2005AR

Abstract

OBJECTIVE

Estimates of the incidence and prevalence of systemic lupus erythematosus (SLE) in the US have varied widely. The purpose of this study was to conduct the California Lupus Surveillance Project (CLSP) to determine credible estimates of SLE incidence and prevalence, with a special focus on Hispanics and Asians.

METHODS

The CLSP, which is funded by the Centers for Disease Control and Prevention, is a population-based registry of individuals with SLE residing in San Francisco County, CA, from January 1, 2007 through December 31, 2009. Data sources included hospitals, rheumatologists, nephrologists, commercial laboratories, and a state hospital discharge database. We abstracted medical records to ascertain SLE cases, which we defined as patients who met ≥4 of the 11 American College of Rheumatology classification criteria for SLE. We estimated crude and age-standardized incidence and prevalence, which were stratified by sex and race/ethnicity.

RESULTS

The overall age-standardized annual incidence rate was 4.6 per 100,000 person-years. The average annual period prevalence was 84.8 per 100,000 persons. The age-standardized incidence rate in women and men was 8.6 and 0.7 per 100,000 person-years, respectively. This rate was highest among black women (30.5), followed by Hispanic women (8.9), Asian women (7.2), and white women (5.3). The age-standardized prevalence in women per 100,000 persons was 458.1 in blacks, 177.9 in Hispanics, 149.7 in Asians, and 109.8 in whites. Capture-recapture modeling estimated 33 additional incident cases and 147 additional prevalent cases.

CONCLUSION

Comprehensive methods that include intensive case-finding provide more credible estimates of SLE in Hispanics and Asians, and confirm racial and ethnic disparities in SLE. The disease burden of SLE is highest in black women, followed by Hispanic women, Asian women, and white women.

Authors+Show Affiliations

University of California, San Francisco.MGC Data Services, Carlsbad, California.California Department of Public Health, Sacramento.Kaiser Permanente, Oakland, California.University of Birmingham, Birmingham, UK.CDC, Atlanta, Georgia.

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

28891237

Citation

Dall'Era, Maria, et al. "The Incidence and Prevalence of Systemic Lupus Erythematosus in San Francisco County, California: the California Lupus Surveillance Project." Arthritis & Rheumatology (Hoboken, N.J.), vol. 69, no. 10, 2017, pp. 1996-2005.
Dall'Era M, Cisternas MG, Snipes K, et al. The Incidence and Prevalence of Systemic Lupus Erythematosus in San Francisco County, California: The California Lupus Surveillance Project. Arthritis & rheumatology (Hoboken, N.J.). 2017;69(10):1996-2005.
Dall'Era, M., Cisternas, M. G., Snipes, K., Herrinton, L. J., Gordon, C., & Helmick, C. G. (2017). The Incidence and Prevalence of Systemic Lupus Erythematosus in San Francisco County, California: The California Lupus Surveillance Project. Arthritis & Rheumatology (Hoboken, N.J.), 69(10), pp. 1996-2005. doi:10.1002/art.40191.
Dall'Era M, et al. The Incidence and Prevalence of Systemic Lupus Erythematosus in San Francisco County, California: the California Lupus Surveillance Project. Arthritis & rheumatology (Hoboken, N.J.). 2017;69(10):1996-2005. PubMed PMID: 28891237.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The Incidence and Prevalence of Systemic Lupus Erythematosus in San Francisco County, California: The California Lupus Surveillance Project. AU - Dall'Era,Maria, AU - Cisternas,Miriam G, AU - Snipes,Kurt, AU - Herrinton,Lisa J, AU - Gordon,Caroline, AU - Helmick,Charles G, Y1 - 2017/09/10/ PY - 2016/12/20/received PY - 2017/06/22/accepted PY - 2017/9/12/pubmed PY - 2017/10/11/medline PY - 2017/9/12/entrez SP - 1996 EP - 2005 JF - Arthritis & rheumatology (Hoboken, N.J.) VL - 69 IS - 10 N2 - OBJECTIVE: Estimates of the incidence and prevalence of systemic lupus erythematosus (SLE) in the US have varied widely. The purpose of this study was to conduct the California Lupus Surveillance Project (CLSP) to determine credible estimates of SLE incidence and prevalence, with a special focus on Hispanics and Asians. METHODS: The CLSP, which is funded by the Centers for Disease Control and Prevention, is a population-based registry of individuals with SLE residing in San Francisco County, CA, from January 1, 2007 through December 31, 2009. Data sources included hospitals, rheumatologists, nephrologists, commercial laboratories, and a state hospital discharge database. We abstracted medical records to ascertain SLE cases, which we defined as patients who met ≥4 of the 11 American College of Rheumatology classification criteria for SLE. We estimated crude and age-standardized incidence and prevalence, which were stratified by sex and race/ethnicity. RESULTS: The overall age-standardized annual incidence rate was 4.6 per 100,000 person-years. The average annual period prevalence was 84.8 per 100,000 persons. The age-standardized incidence rate in women and men was 8.6 and 0.7 per 100,000 person-years, respectively. This rate was highest among black women (30.5), followed by Hispanic women (8.9), Asian women (7.2), and white women (5.3). The age-standardized prevalence in women per 100,000 persons was 458.1 in blacks, 177.9 in Hispanics, 149.7 in Asians, and 109.8 in whites. Capture-recapture modeling estimated 33 additional incident cases and 147 additional prevalent cases. CONCLUSION: Comprehensive methods that include intensive case-finding provide more credible estimates of SLE in Hispanics and Asians, and confirm racial and ethnic disparities in SLE. The disease burden of SLE is highest in black women, followed by Hispanic women, Asian women, and white women. SN - 2326-5205 UR - https://www.unboundmedicine.com/medline/citation/28891237/The_Incidence_and_Prevalence_of_Systemic_Lupus_Erythematosus_in_San_Francisco_County_California:_The_California_Lupus_Surveillance_Project_ L2 - https://doi.org/10.1002/art.40191 DB - PRIME DP - Unbound Medicine ER -