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The Incidence and Prevalence of Systemic Lupus Erythematosus in New York County (Manhattan), New York: The Manhattan Lupus Surveillance Program.
Arthritis Rheumatol. 2017 10; 69(10):2006-2017.AR

Abstract

OBJECTIVE

The Manhattan Lupus Surveillance Program (MLSP) is a population-based registry designed to determine the prevalence of systemic lupus erythematosus (SLE) in 2007 and the incidence from 2007 to 2009 among residents of New York County (Manhattan), New York, and to characterize cases by race/ethnicity, including Asians and Hispanics, for whom data are lacking.

METHODS

We identified possible SLE cases from hospital records, rheumatologist records, and administrative databases. Cases were defined according to the American College of Rheumatology (ACR) classification criteria, the Systemic Lupus International Collaborating Clinics (SLICC) classification criteria, or the treating rheumatologist's diagnosis. Rates among Manhattan residents were age-standardized, and capture-recapture analyses were conducted to assess case underascertainment.

RESULTS

By the ACR definition, the age-standardized prevalence and incidence rates of SLE were 62.2 and 4.6 per 100,000 person-years, respectively. Rates were ∼9 times higher in women than in men for prevalence (107.4 versus 12.5) and incidence (7.9 versus 1.0). Compared with non-Hispanic white women (64.3), prevalence was higher among non-Hispanic black (210.9), Hispanic (138.3), and non-Hispanic Asian (91.2) women. Incidence rates were higher among non-Hispanic black women (15.7) compared with non-Hispanic Asian (6.6), Hispanic (6.5), and non-Hispanic white (6.5) women. Capture-recapture adjustment increased the prevalence and incidence rates (75.9 and 6.0, respectively). Alternate SLE definitions without capture-recapture adjustment revealed higher age-standardized prevalence and incidence rates (73.8 and 6.2, respectively, by the SLICC definition and 72.6 and 5.0 by the rheumatologist definition) than the ACR definition, with similar patterns by sex and race/ethnicity.

CONCLUSION

The MLSP confirms findings from other registries on disparities by sex and race/ethnicity, provides new estimates among Asians and Hispanics, and provides estimates using the SLICC criteria.

Authors+Show Affiliations

New York University School of Medicine, New York, New York.New York University School of Medicine, New York, New York.New York University School of Medicine, New York, New York.New York University School of Medicine, New York, New York.New York University School of Medicine, New York, New York.Hospital for Special Surgery, Weill Cornell Medical College, New York, New York.Columbia University College of Physicians and Surgeons, New York, New York.Columbia University College of Physicians and Surgeons, New York, New York.Columbia University College of Physicians and Surgeons, New York, New York.Icahn School of Medicine at Mount Sinai, New York, New York.State University of New York Downstate College of Medicine, Brooklyn.Albert Einstein College of Medicine, Bronx, New York.University of Birmingham, Birmingham, UK.CDC, Atlanta, Georgia.New York City Department of Health and Mental Hygiene, Long Island City, New York.

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

28891252

Citation

Izmirly, Peter M., et al. "The Incidence and Prevalence of Systemic Lupus Erythematosus in New York County (Manhattan), New York: the Manhattan Lupus Surveillance Program." Arthritis & Rheumatology (Hoboken, N.J.), vol. 69, no. 10, 2017, pp. 2006-2017.
Izmirly PM, Wan I, Sahl S, et al. The Incidence and Prevalence of Systemic Lupus Erythematosus in New York County (Manhattan), New York: The Manhattan Lupus Surveillance Program. Arthritis & rheumatology (Hoboken, N.J.). 2017;69(10):2006-2017.
Izmirly, P. M., Wan, I., Sahl, S., Buyon, J. P., Belmont, H. M., Salmon, J. E., Askanase, A., Bathon, J. M., Geraldino-Pardilla, L., Ali, Y., Ginzler, E. M., Putterman, C., Gordon, C., Helmick, C. G., & Parton, H. (2017). The Incidence and Prevalence of Systemic Lupus Erythematosus in New York County (Manhattan), New York: The Manhattan Lupus Surveillance Program. Arthritis & Rheumatology (Hoboken, N.J.), 69(10), 2006-2017. https://doi.org/10.1002/art.40192
Izmirly PM, et al. The Incidence and Prevalence of Systemic Lupus Erythematosus in New York County (Manhattan), New York: the Manhattan Lupus Surveillance Program. Arthritis & rheumatology (Hoboken, N.J.). 2017;69(10):2006-2017. PubMed PMID: 28891252.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The Incidence and Prevalence of Systemic Lupus Erythematosus in New York County (Manhattan), New York: The Manhattan Lupus Surveillance Program. AU - Izmirly,Peter M, AU - Wan,Isabella, AU - Sahl,Sara, AU - Buyon,Jill P, AU - Belmont,H Michael, AU - Salmon,Jane E, AU - Askanase,Anca, AU - Bathon,Joan M, AU - Geraldino-Pardilla,Laura, AU - Ali,Yousaf, AU - Ginzler,Ellen M, AU - Putterman,Chaim, AU - Gordon,Caroline, AU - Helmick,Charles G, AU - Parton,Hilary, Y1 - 2017/09/10/ PY - 2016/12/20/received PY - 2017/06/22/accepted PY - 2017/9/12/pubmed PY - 2017/10/11/medline PY - 2017/9/12/entrez SP - 2006 EP - 2017 JF - Arthritis & rheumatology (Hoboken, N.J.) VL - 69 IS - 10 N2 - OBJECTIVE: The Manhattan Lupus Surveillance Program (MLSP) is a population-based registry designed to determine the prevalence of systemic lupus erythematosus (SLE) in 2007 and the incidence from 2007 to 2009 among residents of New York County (Manhattan), New York, and to characterize cases by race/ethnicity, including Asians and Hispanics, for whom data are lacking. METHODS: We identified possible SLE cases from hospital records, rheumatologist records, and administrative databases. Cases were defined according to the American College of Rheumatology (ACR) classification criteria, the Systemic Lupus International Collaborating Clinics (SLICC) classification criteria, or the treating rheumatologist's diagnosis. Rates among Manhattan residents were age-standardized, and capture-recapture analyses were conducted to assess case underascertainment. RESULTS: By the ACR definition, the age-standardized prevalence and incidence rates of SLE were 62.2 and 4.6 per 100,000 person-years, respectively. Rates were ∼9 times higher in women than in men for prevalence (107.4 versus 12.5) and incidence (7.9 versus 1.0). Compared with non-Hispanic white women (64.3), prevalence was higher among non-Hispanic black (210.9), Hispanic (138.3), and non-Hispanic Asian (91.2) women. Incidence rates were higher among non-Hispanic black women (15.7) compared with non-Hispanic Asian (6.6), Hispanic (6.5), and non-Hispanic white (6.5) women. Capture-recapture adjustment increased the prevalence and incidence rates (75.9 and 6.0, respectively). Alternate SLE definitions without capture-recapture adjustment revealed higher age-standardized prevalence and incidence rates (73.8 and 6.2, respectively, by the SLICC definition and 72.6 and 5.0 by the rheumatologist definition) than the ACR definition, with similar patterns by sex and race/ethnicity. CONCLUSION: The MLSP confirms findings from other registries on disparities by sex and race/ethnicity, provides new estimates among Asians and Hispanics, and provides estimates using the SLICC criteria. SN - 2326-5205 UR - https://www.unboundmedicine.com/medline/citation/28891252/The_Incidence_and_Prevalence_of_Systemic_Lupus_Erythematosus_in_New_York_County__Manhattan__New_York:_The_Manhattan_Lupus_Surveillance_Program_ L2 - https://doi.org/10.1002/art.40192 DB - PRIME DP - Unbound Medicine ER -