Tags

Type your tag names separated by a space and hit enter

Consumption of whole grains, fruit and vegetables is not associated with indices of renal function in the population-based longitudinal Doetinchem study.
Br J Nutr. 2017 Sep; 118(5):375-382.BJ

Abstract

Emerging evidence suggests that diet and renal function are related. Little is known, however, about the association of consumption of whole grains, fruit and vegetables with urinary albumin:creatinine ratio (ACR) and changes in estimated glomerular filtration rate (eGFR). We investigated this in a population-based cohort aged 26-65 years. Data were from 3787 participants from the Doetinchem cohort study, who were examined ≥3 times, 5 years apart. Consumption of food groups was assessed at each round with a validated FFQ. GFR was estimated at each round from routinely measured cystatin C and creatinine using the Chronic Kidney Disease-Epidemiology (CKD-EPI) equation. ACR was measured at the last round. Generalised estimated equation models were performed to examine associations with changes in eGFR. Linear regression was used to examine associations with ACR. Adjustments were made for covariates related to lifestyle, biological factors and diet. Mean baseline eGFR was 104·5 (sd 13·7) and mean annual decline was -0·95 (sd 0·67) ml/min per 1·73 m2 over a 15-year follow-up. A trend was observed towards slightly less annual decline in eGFR among those with higher consumption of whole grains (P=0·06). This association, however, was attenuated and no longer significant in multivariate models (P=0·29). Consumption of fruit and vegetables was not associated with changes in eGFR and urinary ACR. In conclusion, consumption of whole grains, fruit and vegetables is not associated with changes in eGFR and mean ACR. As this was the first longitudinal study into this association in the general population, and as results are only partially in line with related studies, further research is recommended.

Authors+Show Affiliations

1Centre for Nutrition, Prevention and Health Services,National Institute of Public Health and the Environment,PO Box 1, 3720 BA Bilthoven,The Netherlands.1Centre for Nutrition, Prevention and Health Services,National Institute of Public Health and the Environment,PO Box 1, 3720 BA Bilthoven,The Netherlands.1Centre for Nutrition, Prevention and Health Services,National Institute of Public Health and the Environment,PO Box 1, 3720 BA Bilthoven,The Netherlands.2Department of Internal Medicine and Cardiovascular Research Institute,Maastricht University Medical Center,PO Box 616, 6200 MD Maastricht,The Netherlands.4Department of Nephrology,University Medical Center Groningen,University of Groningen,PO Box 30001,9700 RB Groningen,The Netherlands.4Department of Nephrology,University Medical Center Groningen,University of Groningen,PO Box 30001,9700 RB Groningen,The Netherlands.1Centre for Nutrition, Prevention and Health Services,National Institute of Public Health and the Environment,PO Box 1, 3720 BA Bilthoven,The Netherlands.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

28901886

Citation

Herber-Gast, Gerrie-Cor M., et al. "Consumption of Whole Grains, Fruit and Vegetables Is Not Associated With Indices of Renal Function in the Population-based Longitudinal Doetinchem Study." The British Journal of Nutrition, vol. 118, no. 5, 2017, pp. 375-382.
Herber-Gast GM, Boersma M, Verschuren WMM, et al. Consumption of whole grains, fruit and vegetables is not associated with indices of renal function in the population-based longitudinal Doetinchem study. Br J Nutr. 2017;118(5):375-382.
Herber-Gast, G. M., Boersma, M., Verschuren, W. M. M., Stehouwer, C. D. A., Gansevoort, R. T., Bakker, S. J. L., & Spijkerman, A. M. W. (2017). Consumption of whole grains, fruit and vegetables is not associated with indices of renal function in the population-based longitudinal Doetinchem study. The British Journal of Nutrition, 118(5), 375-382. https://doi.org/10.1017/S0007114517001726
Herber-Gast GM, et al. Consumption of Whole Grains, Fruit and Vegetables Is Not Associated With Indices of Renal Function in the Population-based Longitudinal Doetinchem Study. Br J Nutr. 2017;118(5):375-382. PubMed PMID: 28901886.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Consumption of whole grains, fruit and vegetables is not associated with indices of renal function in the population-based longitudinal Doetinchem study. AU - Herber-Gast,Gerrie-Cor M, AU - Boersma,Marijke, AU - Verschuren,W M Monique, AU - Stehouwer,Coen D A, AU - Gansevoort,Ron T, AU - Bakker,Stephan J L, AU - Spijkerman,Annemieke M W, PY - 2017/9/14/entrez PY - 2017/9/14/pubmed PY - 2017/9/22/medline KW - ACR albumin:creatinine ratio KW - CKD chronic kidney disease KW - MESA Multi-Ethnic Study of Atherosclerosis KW - NOMAS Northern Manhattan Study KW - eGFR estimated glomerular filtration rate KW - Epidemiology KW - Food groups KW - Longitudinal studies KW - Population-based cohorts KW - Renal function SP - 375 EP - 382 JF - The British journal of nutrition JO - Br J Nutr VL - 118 IS - 5 N2 - Emerging evidence suggests that diet and renal function are related. Little is known, however, about the association of consumption of whole grains, fruit and vegetables with urinary albumin:creatinine ratio (ACR) and changes in estimated glomerular filtration rate (eGFR). We investigated this in a population-based cohort aged 26-65 years. Data were from 3787 participants from the Doetinchem cohort study, who were examined ≥3 times, 5 years apart. Consumption of food groups was assessed at each round with a validated FFQ. GFR was estimated at each round from routinely measured cystatin C and creatinine using the Chronic Kidney Disease-Epidemiology (CKD-EPI) equation. ACR was measured at the last round. Generalised estimated equation models were performed to examine associations with changes in eGFR. Linear regression was used to examine associations with ACR. Adjustments were made for covariates related to lifestyle, biological factors and diet. Mean baseline eGFR was 104·5 (sd 13·7) and mean annual decline was -0·95 (sd 0·67) ml/min per 1·73 m2 over a 15-year follow-up. A trend was observed towards slightly less annual decline in eGFR among those with higher consumption of whole grains (P=0·06). This association, however, was attenuated and no longer significant in multivariate models (P=0·29). Consumption of fruit and vegetables was not associated with changes in eGFR and urinary ACR. In conclusion, consumption of whole grains, fruit and vegetables is not associated with changes in eGFR and mean ACR. As this was the first longitudinal study into this association in the general population, and as results are only partially in line with related studies, further research is recommended. SN - 1475-2662 UR - https://www.unboundmedicine.com/medline/citation/28901886/Consumption_of_whole_grains_fruit_and_vegetables_is_not_associated_with_indices_of_renal_function_in_the_population_based_longitudinal_Doetinchem_study_ L2 - https://www.cambridge.org/core/product/identifier/S0007114517001726/type/journal_article DB - PRIME DP - Unbound Medicine ER -