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Norovirus Infection in Older Adults: Epidemiology, Risk Factors, and Opportunities for Prevention and Control.
Infect Dis Clin North Am. 2017 12; 31(4):839-870.ID

Abstract

Norovirus is the leading cause of acute gastroenteritis. In older adults, it is responsible for an estimated 3.7 million illnesses; 320,000 outpatient visits; 69,000 emergency department visits; 39,000 hospitalizations; and 960 deaths annually in the United States. Older adults are particularly at risk for severe outcomes, including prolonged symptoms and death. Long-term care facilities and hospitals are the most common settings for norovirus outbreaks in developed countries. Diagnostic platforms are expanding. Several norovirus vaccines in clinical trials have the potential to reap benefits. This review summarizes current knowledge on norovirus infection in older adults.

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Publisher Full Text
ncbi.nlm.nih.gov
linkinghub.elsevier.com
journals.elsevierhealth.com
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Authors+Show Affiliations

Cardemil CV
Viral Gastroenteritis Branch (proposed), Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: iyk8@cdc.gov.
Parashar UD
Viral Gastroenteritis Branch (proposed), Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Hall AJ
Viral Gastroenteritis Branch (proposed), Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.

MeSH

AgedAged, 80 and overCaliciviridae InfectionsHumansInfection ControlNorovirusNursing HomesRisk FactorsViral Vaccines

Pub Type(s)

Journal Article
Review
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

28911830

Citation

Cardemil, Cristina V., et al. "Norovirus Infection in Older Adults: Epidemiology, Risk Factors, and Opportunities for Prevention and Control." Infectious Disease Clinics of North America, vol. 31, no. 4, 2017, pp. 839-870.
Cardemil CV, Parashar UD, Hall AJ. Norovirus Infection in Older Adults: Epidemiology, Risk Factors, and Opportunities for Prevention and Control. Infect Dis Clin North Am. 2017;31(4):839-870.
Cardemil, C. V., Parashar, U. D., & Hall, A. J. (2017). Norovirus Infection in Older Adults: Epidemiology, Risk Factors, and Opportunities for Prevention and Control. Infectious Disease Clinics of North America, 31(4), 839-870. https://doi.org/10.1016/j.idc.2017.07.012
Cardemil CV, Parashar UD, Hall AJ. Norovirus Infection in Older Adults: Epidemiology, Risk Factors, and Opportunities for Prevention and Control. Infect Dis Clin North Am. 2017;31(4):839-870. PubMed PMID: 28911830.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Norovirus Infection in Older Adults: Epidemiology, Risk Factors, and Opportunities for Prevention and Control. AU - Cardemil,Cristina V, AU - Parashar,Umesh D, AU - Hall,Aron J, Y1 - 2017/09/12/ PY - 2017/9/16/pubmed PY - 2018/5/17/medline PY - 2017/9/16/entrez KW - Gastroenteritis KW - Long-term care KW - Norovirus KW - Older adults KW - Vaccine SP - 839 EP - 870 JF - Infectious disease clinics of North America JO - Infect. Dis. Clin. North Am. VL - 31 IS - 4 N2 - Norovirus is the leading cause of acute gastroenteritis. In older adults, it is responsible for an estimated 3.7 million illnesses; 320,000 outpatient visits; 69,000 emergency department visits; 39,000 hospitalizations; and 960 deaths annually in the United States. Older adults are particularly at risk for severe outcomes, including prolonged symptoms and death. Long-term care facilities and hospitals are the most common settings for norovirus outbreaks in developed countries. Diagnostic platforms are expanding. Several norovirus vaccines in clinical trials have the potential to reap benefits. This review summarizes current knowledge on norovirus infection in older adults. SN - 1557-9824 UR - https://www.unboundmedicine.com/medline/citation/28911830/full_citation L2 - https://linkinghub.elsevier.com/retrieve/pii/S0891-5520(17)30066-1 DB - PRIME DP - Unbound Medicine ER -