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Nodular Hyperplasia of the Bartholin Gland, A Benign Mimicker of Aggressive Angiomyxoma: A Case Series and Literature Review.
Int J Gynecol Pathol. 2018 Nov; 37(6):554-558.IJ

Abstract

Nodular hyperplasia (NH) of the Bartholin gland is an exceedingly rare benign solid lesion of the female genital tract that can mimic the Bartholin gland cyst clinically. The histologic criteria for NH were established in 1998 by Koenig and Tavassoli. In this case series, we describe 4 cases of NH from Women and Infants Hospital in Rhode Island. All cases have microscopic features of lobular proliferation of acini and inspissated mucin. One case especially has extensive mucin extravasation mimicking an aggressive angiomyxoma. In this case series, we call attention to NH as another entity to consider in the differential diagnosis of an enlarged Bartholin gland. We also discuss ways to distinguish it from other benign and malignant solid lesions of the vulvar vestibule.

Authors+Show Affiliations

Department of Pathology and Microbiology (Y.A.T.), University of Nebraska Medical Center, Omaha, Nebraska; Department of Pathology and Laboratory Medicine (Y.A.T., W.D.L., S.E.S.), The Warren Alpert Medical School of Brown University and Women & Infants Hospital, Providence, Rhode Island.No affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

28914673

Citation

Tseng, Yun-An, et al. "Nodular Hyperplasia of the Bartholin Gland, a Benign Mimicker of Aggressive Angiomyxoma: a Case Series and Literature Review." International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists, vol. 37, no. 6, 2018, pp. 554-558.
Tseng YA, Lawrence WD, Slater SE. Nodular Hyperplasia of the Bartholin Gland, A Benign Mimicker of Aggressive Angiomyxoma: A Case Series and Literature Review. Int J Gynecol Pathol. 2018;37(6):554-558.
Tseng, Y. A., Lawrence, W. D., & Slater, S. E. (2018). Nodular Hyperplasia of the Bartholin Gland, A Benign Mimicker of Aggressive Angiomyxoma: A Case Series and Literature Review. International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists, 37(6), 554-558. https://doi.org/10.1097/PGP.0000000000000456
Tseng YA, Lawrence WD, Slater SE. Nodular Hyperplasia of the Bartholin Gland, a Benign Mimicker of Aggressive Angiomyxoma: a Case Series and Literature Review. Int J Gynecol Pathol. 2018;37(6):554-558. PubMed PMID: 28914673.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Nodular Hyperplasia of the Bartholin Gland, A Benign Mimicker of Aggressive Angiomyxoma: A Case Series and Literature Review. AU - Tseng,Yun-An, AU - Lawrence,W Dwayne, AU - Slater,Shahrzad E, PY - 2017/9/16/pubmed PY - 2019/1/22/medline PY - 2017/9/16/entrez SP - 554 EP - 558 JF - International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists JO - Int J Gynecol Pathol VL - 37 IS - 6 N2 - Nodular hyperplasia (NH) of the Bartholin gland is an exceedingly rare benign solid lesion of the female genital tract that can mimic the Bartholin gland cyst clinically. The histologic criteria for NH were established in 1998 by Koenig and Tavassoli. In this case series, we describe 4 cases of NH from Women and Infants Hospital in Rhode Island. All cases have microscopic features of lobular proliferation of acini and inspissated mucin. One case especially has extensive mucin extravasation mimicking an aggressive angiomyxoma. In this case series, we call attention to NH as another entity to consider in the differential diagnosis of an enlarged Bartholin gland. We also discuss ways to distinguish it from other benign and malignant solid lesions of the vulvar vestibule. SN - 1538-7151 UR - https://www.unboundmedicine.com/medline/citation/28914673/Nodular_Hyperplasia_of_the_Bartholin_Gland_A_Benign_Mimicker_of_Aggressive_Angiomyxoma:_A_Case_Series_and_Literature_Review_ L2 - https://doi.org/10.1097/PGP.0000000000000456 DB - PRIME DP - Unbound Medicine ER -