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Medical treatment of inflammatory bowel disease: new therapies, new drugs.
CMAJ. 1987 Nov 01; 137(9):799-802.CMAJ

Abstract

Ulcerative colitis, ulcerative proctitis and Crohn's disease are chronic inflammatory conditions that affect the gastrointestinal tract. Conventional treatment has stressed the role of anti-inflammatory agents to suppress the inflammatory response. New compounds that can deliver 5-aminosalicylic acid to the colon have recently been released in Canada. Metronidazole and azathioprine may also be of benefit in Crohn's disease. Therapy with cyclosporine and clonidine should be based on the results of further clinical trials. The use of nutritional support as primary therapy in Crohn's disease appears promising. At present, both pharmacologic and nutritional therapies should be considered in the treatment of inflammatory bowel disease.

Authors+Show Affiliations

Division of Gastroenterology, University of Calgary, Alta.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

2894889

Citation

Sutherland, L R.. "Medical Treatment of Inflammatory Bowel Disease: New Therapies, New Drugs." CMAJ : Canadian Medical Association Journal = Journal De l'Association Medicale Canadienne, vol. 137, no. 9, 1987, pp. 799-802.
Sutherland LR. Medical treatment of inflammatory bowel disease: new therapies, new drugs. CMAJ. 1987;137(9):799-802.
Sutherland, L. R. (1987). Medical treatment of inflammatory bowel disease: new therapies, new drugs. CMAJ : Canadian Medical Association Journal = Journal De l'Association Medicale Canadienne, 137(9), 799-802.
Sutherland LR. Medical Treatment of Inflammatory Bowel Disease: New Therapies, New Drugs. CMAJ. 1987 Nov 1;137(9):799-802. PubMed PMID: 2894889.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Medical treatment of inflammatory bowel disease: new therapies, new drugs. A1 - Sutherland,L R, PY - 1987/11/1/pubmed PY - 1987/11/1/medline PY - 1987/11/1/entrez SP - 799 EP - 802 JF - CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne JO - CMAJ VL - 137 IS - 9 N2 - Ulcerative colitis, ulcerative proctitis and Crohn's disease are chronic inflammatory conditions that affect the gastrointestinal tract. Conventional treatment has stressed the role of anti-inflammatory agents to suppress the inflammatory response. New compounds that can deliver 5-aminosalicylic acid to the colon have recently been released in Canada. Metronidazole and azathioprine may also be of benefit in Crohn's disease. Therapy with cyclosporine and clonidine should be based on the results of further clinical trials. The use of nutritional support as primary therapy in Crohn's disease appears promising. At present, both pharmacologic and nutritional therapies should be considered in the treatment of inflammatory bowel disease. SN - 0820-3946 UR - https://www.unboundmedicine.com/medline/citation/2894889/Medical_treatment_of_inflammatory_bowel_disease:_new_therapies_new_drugs_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/2894889/ DB - PRIME DP - Unbound Medicine ER -